Does glucocorticoid receptor blockade exacerbate tissue damage after mineralocorticoid/salt administration?

Endocrinology

Volumn 148, Issue 10, 2007, Pages 4829-4835

  Rickard, Amanda J ^a   Funder, John W ^a   Morgan, James ^a   Fuller, Peter J ^a   Young, Morag J ^a  

^a HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; ALDOSTERONE; CORTICOSTERONE; CYCLOOXYGENASE 2; DEOXYCORTICOSTERONE; EPLERENONE; GLUCOCORTICOID RECEPTOR; MIFEPRISTONE; MINERALOCORTICOID; MINERALOCORTICOID RECEPTOR; OSTEOPONTIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; HEART MUSCLE FIBROSIS; HEART VENTRICLE HYPERTROPHY; HISTOLOGY; HYPERTENSION; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MACROPHAGE; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT; STATISTICAL ANALYSIS; SYSTOLIC BLOOD PRESSURE; TISSUE INJURY; UNINEPHRECTOMY;

ANIMALS; BIOLOGICAL MARKERS; BLOOD PRESSURE; CARDIOMEGALY; CARDIOMYOPATHIES; CORONARY VESSELS; DESOXYCORTICOSTERONE; DRUG ADMINISTRATION SCHEDULE; FIBROSIS; HORMONE ANTAGONISTS; MALE; MIFEPRISTONE; MYOCARDIUM; ORGAN SIZE; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GLUCOCORTICOID; SIGNAL TRANSDUCTION; SODIUM CHLORIDE; SPIRONOLACTONE; VASCULITIS;

EID: 34748868104     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2007-0209     Document Type: Article

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