Synthesis of macroporous poly(glycidyl methacrylate) microspheres by surfactant reverse micelles swelling method

European Polymer Journal

Volumn 43, Issue 10, 2007, Pages 4493-4502

  Zhou, Wei Qing ^a,b   Gu, Ting Yue ^c   Su, Zhi Guo ^a   Ma, Guang Hui ^a  

^a INSTITUTE OF PROCESS ENGINEERING   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c Ohio University   (United States)

Author keywords

Macroporous polymers; Phase separation; Surfactant reverse micelles; Suspension polymerization

Indexed keywords

MORPHOLOGY; PHASE SEPARATION; POLYMERIZATION; PORE SIZE; POROUS MATERIALS; SURFACE ACTIVE AGENTS;

GLYCIDYL METHACRYLATE; MACROPOROUS MICROSPHERES; MACROPOROUS POLYMERS; SURFACTANT REVERSE MICELLES SWELLING METHOD;

MICROSPHERES;

EID: 34748859401     PISSN: 00143057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eurpolymj.2007.07.010     Document Type: Article

References (24)

1. Afeyan NB, Regnier FE, Dean RC. Perfusion chromatography. US Patent 5 833 861, 1998.
2. Sherrington D.C. Preparation, structure and morphology of polymer supports. Chem Commun (1998) 2275-2286
3. Horák D., Labský J., and Pilar J. The effect of polymeric porogen on the properties of macroporous poly(glycidyl methacrylate-co-ethylene dimethacrylate). Polymer 34 16 (1993) 3481-3489
4. Afeyan N.B., Fulton S.P., and Regnier F.E. Perfusion chromatography packing materials for proteins and peptides. J Chromatogr 544 (1991) 267-279
5. Fulton S.P., Afeyan N.B., Gordon N.F., and Regnier F.E. Very high speed separation of proteins with a 20-μm reversed-phase sorbent. J Chromatogr A 547 (1991) 452-456
6. McCoy M., Kalghatgi K., Regnier F.E., and Afeyan N.B. Perfusion chromatography - characterization of column packings for chromatography of proteins. J Chromatogr A 743 1 (1996) 221-229
7. Whitney D., McCoy M., Gordon N., and Afeyan N.B. Characterization of large-pore polymeric supports for use in perfusion biochromatography. J Chromatogr A 807 2 (1998) 165-184
8. Barby D, Haq Z. Low density porous cross-linked polymeric materials and their preparation and use as carriers for included liquids. US Patent 4 522 953, 1985.
9. Li NH, Benson JR. Polymeric microbeads and method of preparation. US Patent 5 583 162, 1996.
10. Li NH, Benson JR, Kitagawa N. Polymeric microbeads and method of preparation. US Patent 5 653 922, 1997.
11. Li NH, Benson JR, Kitagawa N. Polymeric microbeads. US Patent 5 863 957, 1999.
12. Li NH, Benson JR, Kitagawa N. Polymeric microbeads and methods of preparation. US Patent 6 100 306, 2000.
13. Wu L., Bai S., and Sun Y. Development of rigid bidisperse porous microspheres for high-speed protein chromatography. Biotechnol Prog 19 4 (2003) 1300-1306
14. Zhang M.L., and Sun Y. Cooperation of solid granule and solvent as porogenic agents novel porogenic mode of biporous media for protein chromatography. J Chromatogr A 922 1 (2001) 77-86
15. Yu Y.H., and Sun Y. Macroporous poly(glycidyl methacrylate - triallyl isocyanurate - divinylbenzene) matrix as an anion-exchange resin for protein adsorption. J Chromatogr A 855 2 (1999) 129-136
16. Zhang M.L., and Sun Y. Poly(glycidyl methacrylate-divinylbenzene-triallylisocyanurate) continuous-bed protein chromatography. J Chromatogr A 912 1 (2001) 31-38
17. Sun G.Y., Shi Q.H., and Sun Y. Novel biporous polymeric stationary phase for high-speed protein chromatography. J Chromatogr A 1061 2 (2004) 159-165
18. Gu T.Y., Zhou W.Q., Su Z.G., and Ma G.H. Rigid gigaporous chromatographic media and their potential impact on downstream processing. China Particuol 3 (2005) 349-353
19. Zhou W.Q., Gu T.Y., Su Z.G., and Ma G.H. Synthesis of macroporous poly(styrene-divinylbenzene) microspheres by surfactant reverse micelles swelling method. Polymer 48 7 (2007) 1981-1988
20. Xu Y.L. Functions of surfactants (2000), Chemical Industry Press, Beijing p. 51-64
21. Higuchi W.L., and Misra J. Physical degradation of emulsions via the molecular diffusion route and the possible prevention thereof. J Pharm Sci 51 5 (1962) 459-466
22. Wang R.W., Zhang Y., Ma G.H., and Su Z.G. Preparation of uniform poly(glycidyl methacrylate) porous microspheres by membrane emulsification-polymerization technology. J Appl Polymer Sci 102 5 (2006) 5018-5027
23. Carlos A., and León y L. New perspectives in mercury porosimetry. Adv Colloid Interf Sci 76-77 (1998) 341-372
24. Okay O. Macroporous copolymer networks. Prog Polym Sci 25 6 (2000) 711-779