The antidepressant tale: Figures signifying nothing?

Advances in Psychiatric Treatment

Volumn 12, Issue 5, 2006, Pages 320-327

  Healy, David ^a,b  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b Hergest Unit   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 34748840578     PISSN: 13555146     EISSN: None     Source Type: Journal    
DOI: 10.1192/apt.12.5.320     Document Type: Review

References (22)

1. American Psychiatric Association (2004) APA Responds to FDA's New Warning on Antidepressants. News Release. 15 October. (http://www.psych.org/news_room/press_releases/ 04-55apaonfdablackboxwarning.pdf). Arlington, VA: APA.
2. American Psychiatric Association & American Academy of Child and Adolescent Psychiatry (2005) ParentsMedGuide. The Use of Medication in Treating Childhood and Adolescent Depression: Information for Patients and Families. http://www.ParentsMedGuide.org.
3. Anthony, P. (2005) FDA 'Drug Watch' early warnings will have lasting negative effect, PhRMA says. Pink Sheets, June 7, no. 001. 14050607001.
4. Beasley, C. M., Dornseif, B. E., Bosomworth, J. C., et al (1991) Fluoxetine and suicide: a meta-analysis of controlled trials of treatment for depression. BMJ, 303, 685-692.
5. Brown, T. & Wilkinson, G. (1998) Critical Reviews in Psychiatry. London: Gaskell.
6. Committee on Safety of Medicines Expert Group on the Safety of Selective Serotonin Reuptake Inhibitors (2004) Report of the CSM Expert Working Group on the Safety of Selective Serotonin Reuptake Inhibitor Antidepressants. London: Medicines and Healthcare products Regulatory Agency. http://www.mhra.gov.uk/home/idcplg?IdcService=GET_FILE&dID= 1391&noSaveAs=1&Rendition=WEB
7. Fassler, D. (2005) FDA's Drug Approval Process: Up to the Challenge? Senate Hearing, 1 March. Washington, DC: US Senate Committee on Health, Education, Labor and Pensions.
8. Fergusson, D., Doucette, S., Cranley-Glass, K., et al (2005) The association between suicide attempts and SSRIs. A systematic review of 677 randomized controlled trials representing 85,470 participants. BMJ, 330, 396-399.
9. Hommes, D. W., Bura, A., Mazzolai, L., et al (1992) Subcutaneous heparin compared with continuous intravenous heparin administration in the initial treatment of deep vein thrombosis. Annals of Internal Medicine, 116, 279-284.
10. Khan, A., Warner, H. A. & Brown, W. A. (2000) Symptom reduction and suicide risk in patients treated with placebo in antidepressant clinical trials. Archives of General Psychiatry, 57, 311-317.
11. Khan, A., Leventhal, R. M., Khan, S., et al (2002) Suicide risk in patients with anxiety disorders: a meta-analysis of the FDA database. Journal of Affective Disorders, 68, 183-190.
12. Khan, A., Khan, S., Kolts, R., et al (2003) Suicide rates in clinical trials of SSRIs, other antidepressants and placebo. Analysis of FDA reports. American Journal of Psychiatry, 160, 790-792.
13. Kirsch, I. & Sapirstein, G. (1998) Listening to prozac but hearing placebo: a meta-analysis of antidepressant medication. Prevention & Treatment, 1, Article 0002a. http://journals. apa.org/ prevention/volume1/pre0010002a.html
14. Kirsch, I., Moore, T. J., Scoboria, A., et al (2002) The emperor's new drugs: an analysis of antidepressant medication data submitted to the US Food and Drugs Administration. Prevention & Treatment, 5, Article 0023a. http://www.alphastim.com/Information/ Technology/Research/Research_PDF/EmperorsNewDrugs.pdf
15. Mann, J. J., Emslie, G., Baldessarini, R. J., et al (2005) SSRIs and suicidal behavior in youth. Neuropsychopharmacology, advance online publication, DOI:10.1038/sj.npp.1300958. http://www.nature.com/ npp/journal/vaop/ncurrent/full/1300958a.html
16. Messori, A., Scrocarro, G. & Martini, N. (1993) Calculation errors in meta-analysis. Annals of Internal Medicine, 118, 77-78.
17. Oxman, A. D., Cook, D. J. & Guyatt, G. H. (1994) Users' guides to the medical literature. VI: How to use an overview. JAMA, 272, 1367-1371.
18. Poole, C. (1987) Beyond the confidence interval. American Journal of Public Health, 77, 195-199.
19. Stang, A., Hense, H.-W., Jockel, H., et al (2005) Is it unethical to use a placebo in a clinical trial? PLoS Medicine, 2, 0177-0180. DOI: 10.1371/journal.pmed.0020072.
20. Rothman, K. J., Lanes, S. & Robins, J. (1993) Casual inference. Epidemiology, 4, 555-556.
21. Teicher, M. H., Glod, C. & Cole, J. O. (1990) Emergence of intense suicidal preoccupation during fluoxetine treatment. American Journal of Psychiatry, 147, 207-210.
22. Wheadon, D. E., Rampey, A. H., Thompson, V. L., et al (1992) Lack of an association between fluoxetine and suicidality in bulimia nervosa. Journal of Clinical Psychiatry, 53, 235-241.