Identification of cell proliferation-associated epitope on CD98 oncoprotein using phage display random peptide library

Cancer Science

Volumn 98, Issue 11, 2007, Pages 1696-1700

  Itoh, Kunihiko ^a   Inoue, Kazuyuki ^b   Hayashi, Hideki ^a   Suzuki, Toshio ^b   Masuko, Takashi ^c  

^a UNIVERSITY OF SHIZUOKA   (Japan)

^b AKITA UNIVERSITY HOSPITAL   (Japan)

^c KINKI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CD98 ANTIGEN; HEPTAPEPTIDE; ONCOPROTEIN; PHENYLALANINE; SERINE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIGEN BINDING; ANTIGEN DETECTION; ANTIGEN FUNCTION; ARTICLE; CANCER CELL; CANCER INHIBITION; CONTROLLED STUDY; EPITOPE MAPPING; GENE AMPLIFICATION; HEAVY CHAIN; MOLECULAR LIBRARY; NONHUMAN; PHAGE DISPLAY; PREDICTION; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN ISOLATION; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANTIGENS, CD; ANTIGENS, CD98; BACTERIOPHAGES; CELL DIVISION; DNA, SINGLE-STRANDED; EPITOPES; HUMANS; NEOPLASM PROTEINS; PEPTIDE FRAGMENTS; PEPTIDE LIBRARY;

EID: 34748824203     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2007.00587.x     Document Type: Article

References (29)

1. Haynes BF, Hemler ME, Mann DL et al. Characterization of a monoclonal antibody (4F2) that binds to human monocytes and to a subset of activated lymphocytes. J Immunol 1981; 126: 1409-14.
2. Broer S, Broer A, Hamprecht B. The 4F2hc surface antigen is necessary for expression of system 1-like neutral amino acid-transport activity in C6-BU-1 rat glioma cells: Evidence from expression studies in Xenopus laevis oocytes. Biochem J 1995; 312: 863-70.
3. Kanai Y, Segawa H, Miyamoto K, Uchino H, Takeda E, Endou H. Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98). J Biol Chem 1998; 273: 23 629-32.
4. Hashimoto Y, Masuko T, Yagita H, Endo N, Kanazawa J, Tazawa J. A proliferation-associated rat cell surface antigen recognized by a murine monoclonal antibody. Gann 1983; 74: 819-21.
5. Masuko T, Abe J, Yagita H, Hashimoto Y. Human bladder cancer cell-surface antigens recognized by murine monoclonal antibodies raised against T24 bladder cancer cells. Jpn J Cancer Res 1985; 76: 386-94.
6. Yagita H, Masuko T, Hashimoto Y. Inhibition of tumor cell growth in vitro by murine monoclonal antibodies that recognize a proliferation-associated cell surface antigen system in rats and humans. Cancer Res 1986; 46: 1478-84.
7. Yagita H, Masuko T, Takahashi N, Hashimoto Y. Monoclonal antibodies that inhibit activation and proliferation of lymphocytes. I. Expression of the antigen on monocytes and activated lymphocytes. J Immunol 1986; 136: 2055-61.
8. Hara K, Kudoh H, Enomoto T, Hashimoto Y, Masuko T. Malignant transformation of NIH3T3 cells by overexpression of early lymphocyte activation antigen CD98. Biochem Biophys Res Commun 1999; 262: 720-5.
9. Smith GP. Filamentous fusion phage: Novel expression vectors that display cloned antigens on the virion surface. Science 1985; 228: 1315-17.
10. Burton DR, Barbas CF, 3rd. Human antibodies from combinatorial libraries. Adv Immunol 1994; 57: 191-280.
11. Winter G, Griffiths AD, Hawkins RE, Hoogenboom HR. Making antibodies by phage display technology. Annu Rev Immunol 1994; 12: 433-55.
12. Itoh K, Nakagomi O, Suzuki K, Inoue K, Tada H, Suzuki T. Recombinant human monoclonal Fab fragments against rotavirus from phage display combinatorial libraries. J Biochem (Tokyo) 1999; 125: 123-9.
13. Hoogenboom HR. Overview of antibody phage-display technology and its applications. Meth Mol Biol 2002; 178: 1-37.
14. Hoogenboom HR. Selecting and screening recombinant antibody libraries. Nat Biotechnol 2005; 23: 1105-16.
15. Dong L, Masaki Y, Takegami T et al. Cloning and expression of two human recombinant monoclonal Fab fragments specific for EBV viral capsid antigen. Int Immunol 2007; 19: 331-6.
16. McLafferty MA, Kent RB, Ladner RC, Markland W. M13 bacteriophage displaying disulfide-constrained microproteins. Gene 1993; 128: 29-36.
17. Sparks AB, Quilliam LA, Der Thorn JMCJ, Kay BK. Identification and characterization of Src SH3 ligands from phage-displayed random peptide libraries. J Biol Chem 1994; 269: 23 853-6.
18. Healy JM, Murayama O, Maeda T, Yoshino K, Sekiguchi K, Kikuchi M. Peptide ligands for integrin alpha v beta 3 selected from random phage display libraries. Biochemistry 1995; 34: 3948-55.
19. Christian RB, Zuckermann RN, Kerr JM, Wang L, Malcolm BA. Simplified methods for construction, assessment and rapid screening of peptide libraries in bacteriophage. J Mol Biol 1992; 227: 711-18.
20. Orlandi R, Menard S, Colnaghi MI, Boyer CM, Felici F. Antigenic and immunogenic mimicry of the HER2/neu oncoprotein by phage-displayed peptides. Eur J Immunol 1994; 24: 2868-73.
21. Bottger V, Bottger A, Lane EB, Spruce BA. Comprehensive epitope analysis of monoclonal anti-proenkephalin antibodies using phage display libraries and synthetic peptides: Revelation of antibody fine specificities caused by somatic mutations in the variable region genes. J Mol Biol 1995; 247: 932-46.
22. Masuko T, Sugahara K, Kozono M et al. A murine monoclonal antibody that recognizes an extracellular domain of the human c-erbB-2 protooncogene product. Jpn J Cancer Res 1989; 80: 10-14.
23. Hara K, Kudoh H, Enomoto T, Hashimoto Y, Masuko T. Enhanced tumorigenicity caused by truncation of the extracellular domain of GP125/ CD98 heavy chain. Oncogene 2000; 19: 6209-15.
24. Binder M, Vogtle FN, Michelfelder S et al. Identification of their epitope reveals the structural basis for the mechanism of action of the immunosuppressive antibodies basiliximab and daclizumab. Cancer Res 2007; 67: 3518-23.
25. Riemer AB, Kurz H, Klinger M, Scheiner O, Zielinski CC, Jensen-Jarolim E. Vaccination with cetuximab mimotopes and biological properties of induced anti-epidermal growth factor receptor antibodies. J Natl Cancer Inst 2005; 97: 1663-70.
26. Li M, Yan Z, Han W, Zhang Y. Mimotope vaccination for epitope-specific induction of anti-CD20 antibodies. Cell Immunol 2006; 239: 136-43.
27. Riemer AB, Klinger M, Wagner S et al. Generation of Peptide mimics of the epitope recognized by trastuzumab on the oncogenic protein Her-2/ neu. J Immunol 2004; 173: 394-401.
28. Riemer AB, Forster-Waldl E, Bramswig KH et al. Induction of IgG antibodies against the GD2 carbohydrate tumor antigen by vaccination with peptide mimotopes. Eur J Immunol 2006; 36: 1267-74.
29. Bolesta E, Kowalczyk A, Wierzbicki A et al. DNA vaccine expressing the mimotope of GD2 ganglioside induces protective GD2 cross-reactive antibody responses. Cancer Res 2005; 65: 3410-18.