Subacute cardiotoxicity caused by anthracycline therapy in children: Can dexrazoxane prevent this effect?

European Journal of Pediatrics

Volumn 166, Issue 11, 2007, Pages 1187-1188

  Kovács, Gábor T ^a   Erlaky, Hajna ^a   Tóth, Kornélia ^a   Horváth, Erzsébet ^b   Szabolcs, Judit ^a   Csóka, Monika ^a   Jókúti, László ^a   Erdélyi, Dániel ^a   Müller, Judit ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE; ANTINEOPLASTIC AGENT; CARDIAC AGENT; DIGITALIS; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FUROSEMIDE; RAZOXANE;

ACUTE TOXICITY; ADVERSE OUTCOME; ARTICLE; CANCER CHEMOTHERAPY; CARDIOTOXICITY; CHILD; COHORT ANALYSIS; CONGESTIVE HEART FAILURE; EWING SARCOMA; FEMALE; FOLLOW UP; HEART FUNCTION; HEART LEFT VENTRICLE FUNCTION; HEART PROTECTION; HUMAN; INCIDENCE; LEUKEMIA; MAJOR CLINICAL STUDY; MALE; OSTEOSARCOMA; PRIORITY JOURNAL; SOFT TISSUE SARCOMA;

ACUTE DISEASE; ANTHRACYCLINES; CARDIOMYOPATHY, DILATED; CARDIOVASCULAR AGENTS; CHILD; FEMALE; HEART; HUMANS; MALE; RAZOXANE; RISK FACTORS;

EID: 34748814885     PISSN: 03406199     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00431-006-0370-2     Document Type: Article

References (6)

1. Cvetkovic RS, Scott L (2005) Dexrazoxane: a review of its use for cardioprotection during anthracycline chemotherapy. Drugs 65:1005-1024, 2005
2. Elbl L, Hrstkova H, Tomaskova I, Blazek B, Michalek J (2005) Long-term serial echocardiographic examination of late anthracycline toxicity and its prevention by dexrazoxane in paediatric patients. Eur J Pediatr 164:678-684
3. Greiner MA, Lipschultz SE (1998) Epidemiology of anthracycline cardiotoxicity in children and adults. Seminar Oncol 25[uppl 10]:72-85
4. Kremer LCM, Van Dalen EC, Offriga M, Ottenkamp J, Voute PA (2001) Anthracycline induced clinical heart failure in a cohort of 607 children: long-term follow-up study. J Clin Oncol 19:191-196
5. Lipschultz SE (2006) Exposure to anthracyclines during childhood causes cardiac injury. Semin Oncol 33[S8]:8-14
6. Wouters KA, Kremer LC, Miller TL, Herman EH, Lipschultz SE (2005) Protecting against antracycline-induced myocardial damage: a review of the most promising strategies. Br J Haematol 131:561-578