Correlation of clinical, histological, and cytokeratin profiles of squamous cell carcinoma of the oral tongue with prognosis

International Journal of Surgical Pathology

Volumn 15, Issue 4, 2007, Pages 376-383

  Dantas Da Silveira, Ericka Janine ^a   Pina Godoy, Gustavo ^b   AlvesUchôa Lins, Ruthinéia Diógenes ^b   Silva Arruda, Maria De Lourdes ^c   Formiga Ramos, Carlos Cesar ^c   De Almeida Freitas, Roseana ^a   Guedes Queiroz, Lélia Maria ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE   (Brazil)

^b STATE UNIVERSITY OF PARAÍBA   (Brazil)

^c Luiz Antonio Hospital   (Brazil)

Author keywords

Histological grading; Immunohistochemistry; Metastases; TNM classification; Tongue squamous cell carcinoma

Indexed keywords

CYTOKERATIN; CYTOKERATIN 10; CYTOKERATIN 13; CYTOKERATIN 14; CYTOKERATIN 16; CYTOKERATIN 19; CYTOKERATIN 7;

ADULT; AGED; ARTICLE; CANCER STAGING; CLINICAL ARTICLE; CORRELATION ANALYSIS; FEMALE; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; METASTASIS; MORPHOLOGY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA; STATISTICAL ANALYSIS; TONGUE CARCINOMA;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; COMBINED MODALITY THERAPY; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; KERATINS; MALE; MIDDLE AGED; REMISSION INDUCTION; RETROSPECTIVE STUDIES; SURVIVAL RATE; TONGUE NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 34748812621     PISSN: 10668969     EISSN: None     Source Type: Journal    
DOI: 10.1177/1066896907304992     Document Type: Article

References (22)

1. Allison PJ, Locker D., Feine JS The role of diagnostic delays in the prognosis of oral cancer: a review of the literature. Oral Oncol. 1998 ; 34: 161-170.
2. Malone JP, Stephens JA, Grecula JC, Rhoades CA, Ghaheri BA, Schuller DE Disease control, survival, and functional outcome after multimodal treatment for advanced-stage tongue base cancer. Head Neck. 2004 ; 26: 561-572.
3. Bryne M. Is the invasive front of an oral carcinoma the most important area for prognostication? Oral Dis. 1998 ; 4: 70-77.
4. Todd R., Donoff RB, Wong Dtw. The molecular biology of oral carcinogenesis: toward a tumor progression model. J Oral Maxillofac Surg. 1997 ; 55: 613-623.
5. O-Charoenrat P., Pillai G., Patel S., et al. Tumour thickness predicts cervical nodal metastases and survival in early oral tongue cancer. Oral Oncol. 2003 ; 39: 386-390.
6. Okada Y., Mataga I., Katagiri M., Ishii K. An analysis of cervical lymph nodes metastasis in oral squamous cell carcinoma. Relationship between grade of histopathological malignancy and lymph nodes metastasis. Int J Oral Maxillofac Surg. 2003 ; 32: 284-288.
7. Rajhi NA, Khafaga Y., El-Husseiny J., et al. Early stage carcinoma of oral tongue: prognostic factors for local control and survival. Oral Oncol. 2000 ; 36: 508-514.
8. Hiratsuka H., Miyakawa A., Nakamori K., Kido Y., Sunakawa H., Kohama G. Multivariate analysis of occult lymph node metastasis as a prognostic indicator for patients with squamous cell carcinoma of the oral cavity. Cancer. 1997 ; 80: 351-356.
9. Takes RP, Robert JB, Martijn Ajrc, et al. Markers for nodal metastasis in head and neck squamous cell cancer. Arch Otolaryngol. 2002 ; 128: 512-517.
10. Nithya C., Pandey M., Naik B., Ahamed IM Patterns of cervical metastasis from carcinoma of the oral tongue. World J Surg Oncol. 2003 ; 1: 10-15.
11. Miranda JL Expressão de proteínas da matriz extracelular em carcinoma epidermóide de lábio inferior e língua [doctoral thesis]. Natal -RN, Brazil: Departamento de Odontologia da UFRN.
12. Sawair FA, Irwin CR, Gordon DJ, Leonard AG, Stephenson M., Napier SS Invasive front grading: reliability and usefulness in the management of oral squamous cell carcinoma. J Oral Pathol Med. 2003 ; 32: 1-9.
13. Silva JV Expressão das citoqueratinas em carcinomas de células escamosas orais [doctoral thesis]. São Paulo, Brazil: Faculdade de Odontologia da Universidade de São Paulo.
14. Xu XC, Lee JS, Lippman SM, Ro JY, Hong WK, Lotan R. Increased expression of cytokeratins CK8 and CK19 is associated with head and neck carcinogenesis. Cancer Epidemiol Biomarkers Prev. 1995 ; 4: 871-876.
15. Morgan PR, Lan SU Intermediate filaments in oral neoplasia. I. Oral cancer and epithelial dysplasia. Eur J Cancer B Oral Oncol. 1994 ; 30B: 160-166.
16. Depondt J., Shabana AH, Sawaf H., Gehanno P., Forest N. Cytokeratin alterations as diagnostic and prognostic markers of oral and pharyngeal carcinomas. A prospective study. Eur J Oral Sci. 1999 ; 107: 442-454.
17. Boisnic S., Ouhayoun JP, Branchet MC, et al. Alteration of cytokeratin expression in oral lichen planus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1995 ; 79: 207-215.
18. Su L., Morgan PR, Lane EB Keratin 14 and 19 expression in normal, dysplastic and malignant oral epithelia. A study using in situ hybridization and immunohistochemistry. J Oral Pathol Med. 1996 ; 25: 293-301.
19. Bongers V., Snow GB, Vries N., Braakhuis BJ Potential early markers of carcinogenesis in the mucosa of head and neck using exfoliative cytology. J Pathol. 1996 ; 178: 284-289.
20. Sawaf MH, Ouhayoun JP, Forest N. Cytokeratin profiles in oral epithelia: a review and new classification. J Biol Buccale. 1991 ; 19: 187-198.
21. Ogden GR, Chisholm DM, Adi M., Lane EB Cytokeratin expression in oral cancer and its relationship to tumor differentiation. J Oral Pathol Med. 1993 ; 22: 82-86.
22. El-Salahy EM Evaluation of cytokeratin-19 & cytokeratin-20 and interleukin-6 in Egyptian bladder cancer patients. Clin Biochem. 2002 ; 35: 607-613.