Clinical complete long-term remission of a patient with metastatic malignant melanoma under therapy with indisulam (E7070)

Melanoma Research

Volumn 17, Issue 5, 2007, Pages 329-331

  Baur, Martina ^a,b   Gneist, Margit ^a   Owa, Takashi ^c   Dittrich, Christian ^a,b  

^a LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

^b KAISER FRANZ JOSEF HOSPITAL   (Austria)

^c EISAI CO LTD   (Japan)

Author keywords

E7070; Genotyping; Indisulam; Melanoma

Indexed keywords

ACYL COENZYME A DEHYDROGENASE VERY LONG CHAIN; ANTINEOPLASTIC AGENT; CHLOROINDOLYLSULFONAMIDE CELL CYCLE INHIBITOR; INDISULAM; MITOCHONDRIAL 2 OXOGLUTARATE CARRIER PROTEIN; NADH DEHYDROGENASE (QUINONE) FLAVOPROTEIN 1; NADH DEHYDROGENASE (UBIQUINONE) 1 BETA SUBCOMPLEX 8; NADH DEHYDROGENASE (UBIQUINONE) IRON SULFUR PROTEIN 1; PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CANCER CHEMOTHERAPY; CANCER DIAGNOSIS; CANCER GROWTH; CANCER REGRESSION; CASE REPORT; CERVICAL LYMPH NODE; DNA MICROARRAY; DRUG DOSE ESCALATION; ENERGY METABOLISM; ENERGY YIELD; GENE CONTROL; GENE EXPRESSION; HUMAN; HUMAN TISSUE; LUNG METASTASIS; LYMPH NODE BIOPSY; MELANOMA; METASTASIS; MITOCHONDRIAL ENERGY TRANSFER; PRIORITY JOURNAL; SKIN DEFECT; TUMOR BIOPSY;

ANTINEOPLASTIC AGENTS; HUMANS; LYMPH NODES; LYMPHATIC METASTASIS; MALE; MELANOMA; MIDDLE AGED; REMISSION INDUCTION; SKIN NEOPLASMS; SULFONAMIDES;

EID: 34648854471     PISSN: 09608931     EISSN: None     Source Type: Journal    
DOI: 10.1097/CMR.0b013e3282ef4189     Document Type: Article

References (2)

1. Dittrich Ch, Dumez H, Calvert H, Hanauske A, Faber M, Wanders J, et al. Phase I and pharmacokinetic study of E7070, a chloroindolyl-sulfonamide anticancer agent, administered on a weekly schedule to patients with solid tumors. Clin Cancer Res 2003; 9:5195-5204.
2. Smyth JF, Aamdal S, Awada A, Dittrich C, Caponigro F, Schöffski P, et al. On behalf of the EORTC New Drug Development and Melanoma Groups. Phase II study of E7070 in patients with metastatic melanoma. Ann Oncol 2005; 16:158-161.