Effect of two-hour daily hemodialysis and sham dialysis on breath isoprene exhalation

International Journal of Artificial Organs

Volumn 30, Issue 7, 2007, Pages 583-588

  Capodicasa, E ^a   Brunori, F ^a   De Medio, G E ^a   Pelli, M A ^a   Vecchi, L ^b   Buochristiani, Umberto ^b  

^a UNIVERSITY OF PERUGIA   (Italy)

^b Department of Nefrology   (Italy)

Author keywords

Daily hemodialysis; Human breath; Isoprene; Sham hemodialysis

Indexed keywords

BLOOD PRESSURE; GAS CHROMATOGRAPHY; HEMODIALYZERS; ISOPRENE; METABOLISM;

DAILY HEMODIALYSIS; DIALYSATES; HAEMODIALYSIS; HUMAN BREATH; HUMAN ORGANISMS; PARALLEL ANALYSIS; PERITONEAL DIALYSIS; SHAM HEMODIALYSIS; VOLATILE HYDROCARBONS;

DIALYSIS;

ISOPRENE; MEVALONIC ACID;

AMBIENT AIR; ARTICLE; BLOOD PRESSURE MONITORING; BREATH ANALYSIS; CLINICAL ARTICLE; CLINICAL EVALUATION; CONTROLLED STUDY; DIALYSIS MEMBRANE; EXHALATION; GAS CHROMATOGRAPHY; HEART RATE; HEMODIALYSIS; HEMODYNAMICS; HUMAN; KIDNEY BLOOD FLOW; KIDNEY FAILURE; TREATMENT DURATION;

EID: 34648836715     PISSN: 03913988     EISSN: None     Source Type: Journal    
DOI: 10.1177/039139880703000705     Document Type: Article

References (23)

1. Fenske JD, Paulson SE. Human breath emissions of VOCs. J Air Waste Manag Assoc 1999; 49: 594-8.
2. Watson WP, Cottrell L, Zhang D, Golding BT. Metabolism and molecular toxicology of isoprene. Chem Biol Interact 2001; 135-136: 223-38.
3. Bird MG, Rice JM, Bond JA. Evaluation of 1,3-butadiene, isoprene and chloroprene health risks. Chem Biol Interact 2001; 135-136: 1-7.
4. Golding BT, Cottrell L, Mackay D, et al. Stereochemical and kinetic comparisons of mono- and diepoxide formation in the in vitro metabolism of isoprene by liver microsomes from rats, mice, and humans. Chem Res Toxicol 2003; 16: 933-944.
5. Hinson DD, Chambliss KL, Toth MJ, et al. Post-translational regulation of mevalonate kinase by intermediates of the cholesterol and nonsterol isoprene biosynthetic pathways. J Lipid Res 1997: 38: 2216-23.
6. Houten SM, Romeijn GJ, Koster J, et al. Identification and characterization of three novel missense mutations in mevalonate kinase cDNA causing mevalonic aciduria, a disorder of isoprene biosynthesis. Hum Mol Genet 1999; 8: 1523-8.
7. Capodicasa E, Trovarelli G, De Medio GE, et al. Volatile alkanes and increased concentrations of isoprene in exhaled air during hemodialysis. Nephron 1999; 82: 331-7.
8. Trovarelli G, Brunori F, De Medio GE, et al. Onset, time course, and persistence of increased haemodialysis-induced breath isoprene emission. Nephron 2001; 88: 44-7.
9. Lirk P, Bodrogi F, Raifer H, et al. Elective haemodialysis increases exhaled isoprene. Nephrol Dial Transplant 2003; 18: 937-41.
10. Davies S, Spanel P, Smith D. A new "online" method to measure increased exhaled isoprene in end-stage renal failure. Nephrol Dial Transplant 2001; 16: 836-9.
11. Capodicasa E, Trovarelli G, Brunori F, et al. Lack of isoprene overproduction during peritoneal dialysis. Perit Dial Int 2002; 22: 48-52.
12. Locatelli F, Manzoni C. Treatment modalities in comparison: when do clinical differences emerge? Nephrol Dial Transplant 2000; 15 (suppl 1): S29-35.
13. Murphy SW, Foley RN, Barrett BJ, et al. Comparative hospitalization of hemodialysis and peritoneal dialysis patients in Canada. Kidney Int 2000; 57: 2557-63.
14. Murphy SW, Foley RN, Barrett BJ, et al. Comparative mortality of hemodialysis and peritoneal dialysis in Canada. Kidney Int 2000; 57: 1720-6.
15. Misra M, Nolph KD. Adequacy in dialysis: intermittent versus continuous therapies. Nefrologia 2000; 20 (suppl 3): S25-32.
16. Scoppola A, De Paolis P, Menzinger G, Lala A, Di Giulio S. Plasma mevalonate concentrations in uremic patients. Kidney Int 1997; 51: 908-12.
17. Fagugli RM, De Smet R, Buoncristiani U, et al. Behavior of non-protein-bound and protein-bound uremic solutes during daily hemodialysis. Am J Kidney Dis 2002; 40: 339-47.
18. Floridi A, Antolini F, Galli F, et al. Daily haemodialysis improves indices of protein glycation. Nephrol Dial Transplant 2002; 17: 871-8.
19. Buoncristiani U, Cairo G, Giombini L, Quintaliani G, Bonforte G. Dramatic improvement of clinical-metabolic parameters and quality of life with daily dialysis. Int J Artif Organs 1989; 12 (suppl 4): S133-6.
20. Karl T, Prazeller P, Mayr D, et al. Human breath isoprene and its relation to blood cholesterol levels: new measurements and modeling. J Appl Physiol 2001; 91: 762-70.
21. Capodicasa E, Trovarelli G, De Medio GE, et al. Volatile alkanes and increased concentrations of isoprene in exhaled air during hemodialysis. Nephron 1999; 82: 331-7.
22. Melnick RL, Sills RC, Roycroft JH, et al. Isoprene, an endogenous hydrocarbon and industrial chemical, induces multiple organ neoplasia in rodents after 26 weeks of inhalation exposure. Cancer Res 1994; 54: 5333-9.
23. Melnik RL. Carcinogenicity and mechanistic insights on the behavior of epoxides and epoxide-forming chemicals. Ann N Y Acad Sci 2002; 982: 177-89.