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Volumn 21, Issue 10, 2007, Pages 766-769

Renin inhibition: The holy grail of renin-angiotensin system blockade?

Author keywords

[No Author keywords available]

Indexed keywords

ALISKIREN; ANGIOTENSIN I; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; INSULIN; IRBESARTAN; LISINOPRIL; LOSARTAN; PLACEBO; RENIN; RENIN INHIBITOR; THIAZIDE DIURETIC AGENT; VALSARTAN;

EID: 34648831723     PISSN: 09509240     EISSN: 14765527     Source Type: Journal    
DOI: 10.1038/sj.jhh.1002221     Document Type: Note
Times cited : (11)

References (28)
  • 1
    • 34548855067 scopus 로고    scopus 로고
    • Strasser RH, Puig JG, Farsang C, Croket M, Li J, Van Ingen H. A comparison of the tolerability of the direct renin inhibitor aliskiren and lisinopril in patients with severe hypertension. J Hum Hypertens 2007; 21: 780-787 (this issue).
    • Strasser RH, Puig JG, Farsang C, Croket M, Li J, Van Ingen H. A comparison of the tolerability of the direct renin inhibitor aliskiren and lisinopril in patients with severe hypertension. J Hum Hypertens 2007; 21: 780-787 (this issue).
  • 2
    • 31444453963 scopus 로고    scopus 로고
    • Renin angiotensin system inhibition in hypertension
    • Ibrahim MM. Renin angiotensin system inhibition in hypertension. J Hum Hypertens 2006; 20: 101-108.
    • (2006) J Hum Hypertens , vol.20 , pp. 101-108
    • Ibrahim, M.M.1
  • 3
    • 0015506533 scopus 로고
    • Propranolol inhibition of renin secretion: A specific approach to diagnosis and treatment of renin-dependent hypertensive diseases
    • Bühler FR, Laragh JH, Baer J, Vaughan Jr ED, Brunner HR. Propranolol inhibition of renin secretion: A specific approach to diagnosis and treatment of renin-dependent hypertensive diseases. N Engl J Med 1972; 287: 1209-1214.
    • (1972) N Engl J Med , vol.287 , pp. 1209-1214
    • Bühler, F.R.1    Laragh, J.H.2    Baer, J.3    Vaughan Jr, E.D.4    Brunner, H.R.5
  • 4
    • 0033867383 scopus 로고    scopus 로고
    • Intermediate but not low dose aspirin can suppress angiotensin-converting enzyme inhibitor-induced cough
    • Tenenbaum A, Grossman E, Shemesh J, Fisman EZ, Nosrati I, Motro M. Intermediate but not low dose aspirin can suppress angiotensin-converting enzyme inhibitor-induced cough. Am J Hypertens 2000; 13: 776-782.
    • (2000) Am J Hypertens , vol.13 , pp. 776-782
    • Tenenbaum, A.1    Grossman, E.2    Shemesh, J.3    Fisman, E.Z.4    Nosrati, I.5    Motro, M.6
  • 6
    • 34648879615 scopus 로고
    • Hypertension in man. Exposure of the renin and sodium components using angiotensin II blockade
    • Brunner HR, Gavras H, Laragh JH, Keenan R. Hypertension in man. Exposure of the renin and sodium components using angiotensin II blockade. Circ Res 1974; 24(Suppl 1): 135-143.
    • (1974) Circ Res , vol.24 , Issue.SUPPL. 1 , pp. 135-143
    • Brunner, H.R.1    Gavras, H.2    Laragh, J.H.3    Keenan, R.4
  • 7
    • 20544440652 scopus 로고    scopus 로고
    • Renin inhibition: What are the therapeutic opportunities?
    • Fisher NDL, Hollenberg NK. Renin inhibition: What are the therapeutic opportunities? J Am Soc Nephrol 2005; 16:292-299.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 292-299
    • Fisher, N.D.L.1    Hollenberg, N.K.2
  • 8
    • 0028278186 scopus 로고
    • Pharmacology of renin inhibitors and their application to the treatment of hypertension
    • Wood J, Cumin F, Maibaum J. Pharmacology of renin inhibitors and their application to the treatment of hypertension. Pharmacol Ther 1994; 61: 325-344.
    • (1994) Pharmacol Ther , vol.61 , pp. 325-344
    • Wood, J.1    Cumin, F.2    Maibaum, J.3
  • 9
    • 0000586975 scopus 로고
    • The preparation, purification and amino acid sequence of a polypeptide renin substrate
    • Skeggs Jr LT, Kahn JR, Lentz K, Shumway NP. The preparation, purification and amino acid sequence of a polypeptide renin substrate. J Exp Med 1957; 106: 439-453.
    • (1957) J Exp Med , vol.106 , pp. 439-453
    • Skeggs Jr, L.T.1    Kahn, J.R.2    Lentz, K.3    Shumway, N.P.4
  • 10
    • 0031688757 scopus 로고    scopus 로고
    • Pathways for angiotensin II generation in intact human tissue: Evidence from comparative pharmacological interruption of the renin system
    • Hollenberg NK, Fisher ND, Price DA. Pathways for angiotensin II generation in intact human tissue: Evidence from comparative pharmacological interruption of the renin system. Hypertension 1998; 32: 387-392.
    • (1998) Hypertension , vol.32 , pp. 387-392
    • Hollenberg, N.K.1    Fisher, N.D.2    Price, D.A.3
  • 11
    • 0026918244 scopus 로고
    • The renin system and four lines of hypertension research: Nephron heterogeneity, the calcium connection, and the prorenin vasodilator limb and plasma renin and heart attack
    • Laragh JH. The renin system and four lines of hypertension research: nephron heterogeneity, the calcium connection, and the prorenin vasodilator limb and plasma renin and heart attack. Hypertension 1992; 2: 267-279.
    • (1992) Hypertension , vol.2 , pp. 267-279
    • Laragh, J.H.1
  • 12
    • 0025794059 scopus 로고
    • Association of the renin-sodium profile with the risk of myocardial infarction in patients with hypertension
    • Alderman MH, Madhavan SH, Ooi WL, Cohen H, Sealey JE, Laragh JH. Association of the renin-sodium profile with the risk of myocardial infarction in patients with hypertension. N Engl J Med 1991; 324: 1098-1104.
    • (1991) N Engl J Med , vol.324 , pp. 1098-1104
    • Alderman, M.H.1    Madhavan, S.H.2    Ooi, W.L.3    Cohen, H.4    Sealey, J.E.5    Laragh, J.H.6
  • 14
    • 0021889169 scopus 로고
    • Increased plasma renin activity in diabetes mellitus: A marker of microvascular complications
    • Luetscher JA, Kraemer FB, Wilson DM, Schwartz HC, Bryer-Ash M. Increased plasma renin activity in diabetes mellitus: A marker of microvascular complications. N Engl J Med 1985; 312: 1412-1417.
    • (1985) N Engl J Med , vol.312 , pp. 1412-1417
    • Luetscher, J.A.1    Kraemer, F.B.2    Wilson, D.M.3    Schwartz, H.C.4    Bryer-Ash, M.5
  • 15
    • 0029970514 scopus 로고    scopus 로고
    • Renin inhibition: A novel therapy for cardiovascular disease
    • Lin C, Frishman WH. Renin inhibition: A novel therapy for cardiovascular disease. Am Heart J 1996; 131; 1024-1034.
    • (1996) Am Heart J , vol.131 , pp. 1024-1034
    • Lin, C.1    Frishman, W.H.2
  • 16
    • 0036266596 scopus 로고    scopus 로고
    • Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin
    • Nguyen G, Delarue F, Burckle C, Bouzhir L, Giller T, Straer J-D. Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest 2002; 10: 1417-1427.
    • (2002) J Clin Invest , vol.10 , pp. 1417-1427
    • Nguyen, G.1    Delarue, F.2    Burckle, C.3    Bouzhir, L.4    Giller, T.5    Straer, J.-D.6
  • 17
    • 0023189241 scopus 로고
    • Inhibitors of renin as potential therapeutic agents
    • Wood JM, Stanton JL, Hofbauer KG. Inhibitors of renin as potential therapeutic agents. J Enzym Inhib 1987; 1: 169-185.
    • (1987) J Enzym Inhib , vol.1 , pp. 169-185
    • Wood, J.M.1    Stanton, J.L.2    Hofbauer, K.G.3
  • 18
    • 33645061521 scopus 로고    scopus 로고
    • Evidence for renoprotection by blockade of the reiiin-angiotensin-aldosterone system in hypertension and diabetes
    • Karalliedde J, Viberti G. Evidence for renoprotection by blockade of the reiiin-angiotensin-aldosterone system in hypertension and diabetes. J Hum Hypertens. 2006; 20: 239-253.
    • (2006) J Hum Hypertens , vol.20 , pp. 239-253
    • Karalliedde, J.1    Viberti, G.2
  • 21
    • 0036372173 scopus 로고    scopus 로고
    • Angiotensin II suppression in humans by the orally active renin inhibitor aliskiren (SPP 100). Comparison with enalapril
    • Nussberger J, Wuerzner G, Jensen C, Brunner HR. Angiotensin II suppression in humans by the orally active renin inhibitor aliskiren (SPP 100). Comparison with enalapril. Hypertension 2002; 39: e1-e8.
    • (2002) Hypertension , vol.39
    • Nussberger, J.1    Wuerzner, G.2    Jensen, C.3    Brunner, H.R.4
  • 22
    • 33947182655 scopus 로고    scopus 로고
    • Aliskiren, an oral renin inhibitor, provides dose-dependent efficacy and sustained 24-h blood pressure control in patients with hypertension
    • Oh B-H, Mitchell J, Herron JR, Chung J, Khan M, Keefe DL. Aliskiren, an oral renin inhibitor, provides dose-dependent efficacy and sustained 24-h blood pressure control in patients with hypertension. J Am Coll Cardiol 2007; 49: 1157-1163.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 1157-1163
    • Oh, B.-H.1    Mitchell, J.2    Herron, J.R.3    Chung, J.4    Khan, M.5    Keefe, D.L.6
  • 23
    • 0347479295 scopus 로고    scopus 로고
    • Blood pressure lowering in essential hypertension with an oral renin inhibitor, aliskiren
    • Stanton A, Jensen C, Nussberger J, O'Brien E. Blood pressure lowering in essential hypertension with an oral renin inhibitor, aliskiren. Hypertension 2003; 42: 1137-1143.
    • (2003) Hypertension , vol.42 , pp. 1137-1143
    • Stanton, A.1    Jensen, C.2    Nussberger, J.3    O'Brien, E.4
  • 24
    • 14844363404 scopus 로고    scopus 로고
    • Gradman AH, Schmieder RE, Lins RL, Nussberger J, Chiang Y, Bedigian W. Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients. Circulation 2005; 111: 1012-1018.
    • Gradman AH, Schmieder RE, Lins RL, Nussberger J, Chiang Y, Bedigian W. Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients. Circulation 2005; 111: 1012-1018.
  • 25
    • 33846421005 scopus 로고    scopus 로고
    • Aliskiren reduces blood pressure and suppresses plasma renin activity in combination with a thiazide diuretic, an angiotensin-converting enzyme inhibitor, or an angiotensin receptor blocker
    • O'Brien E, Barton J, Nussberger J, Mulcahy D, Jensen C, Dicker P et al. Aliskiren reduces blood pressure and suppresses plasma renin activity in combination with a thiazide diuretic, an angiotensin-converting enzyme inhibitor, or an angiotensin receptor blocker. Hypertension 2007; 49: 276-284.
    • (2007) Hypertension , vol.49 , pp. 276-284
    • O'Brien, E.1    Barton, J.2    Nussberger, J.3    Mulcahy, D.4    Jensen, C.5    Dicker, P.6
  • 26
    • 33845366982 scopus 로고    scopus 로고
    • Renin inhibition with aliskiren provides additive antihypertensive efficacy when used in combination with hydrochlorothiazide
    • Villamil A, Chrysant SG, Camoun D, Schober B, Hsu H, Matrisciano-Dimichino L et al. Renin inhibition with aliskiren provides additive antihypertensive efficacy when used in combination with hydrochlorothiazide. J Hypertens 2007; 25: 217-226.
    • (2007) J Hypertens , vol.25 , pp. 217-226
    • Villamil, A.1    Chrysant, S.G.2    Camoun, D.3    Schober, B.4    Hsu, H.5    Matrisciano-Dimichino, L.6
  • 27
    • 0034100147 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of angiotensin II-mediated cardiovascular and renal disease
    • Kim S, Iwao H. Molecular and cellular mechanisms of angiotensin II-mediated cardiovascular and renal disease. Pharmacol Rev 2000; 52: 11-34.
    • (2000) Pharmacol Rev , vol.52 , pp. 11-34
    • Kim, S.1    Iwao, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.