A developmental perspective on the controversy surrounding the use of SSRIs to treat pediatric depression

American Journal of Psychiatry

Volumn 164, Issue 9, 2007, Pages 1304-1306

  Leckman, James F ^a   King, Robert A ^b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CITALOPRAM; FLUOXETINE; PLACEBO; SEROTONIN TRANSPORTER; SEROTONIN UPTAKE INHIBITOR;

ANXIETY; ANXIETY DISORDER; BIPOLAR DISORDER; CLINICAL TRIAL; DRUG EXPOSURE; DRUG RESEARCH; EDITORIAL; EMOTIONALITY; FOLLOW UP; HUMAN; MAJOR DEPRESSION; MENTAL DISEASE; META ANALYSIS; MOTOR DYSFUNCTION; NONHUMAN; OBSESSIVE COMPULSIVE DISORDER; PATIENT ATTITUDE; PATIENT MONITORING; PRIORITY JOURNAL; PROTEIN EXPRESSION; RISK ASSESSMENT; SEXUAL BEHAVIOR; SUICIDAL IDEATION; SYSTEMATIC REVIEW; TREATMENT RESPONSE;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGE FACTORS; BIPOLAR DISORDER; CENTRAL NERVOUS SYSTEM; CHILD; CHILD DEVELOPMENT; CHILD, PRESCHOOL; DEPRESSIVE DISORDER; DRUG LABELING; HUMANS; RISK FACTORS; SEROTONIN UPTAKE INHIBITORS; UNITED STATES; UNITED STATES FOOD AND DRUG ADMINISTRATION;

EID: 34648822792     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/appi.ajp.2007.07050880     Document Type: Editorial

References (14)

1. Zito JM, Safer DJ, DosReis S, Gardner JF, Magder L, Soeken K, Boles M, Lynch F, Riddle MA: Psychotropic practice patterns for youth: a 10-year perspective. Arch Pediatr Adolesc Med 2003; 157:17-25
2. Zito JM, Safer DJ, dosReis S, Gardner JF, Boles M, Lynch F: Trends in the prescribing of psychotropic medications to preschoolers. JAMA 2000; 283:1025-1030
3. Gibbons RD, Hur K, Bhaumik DK, Mann JJ: The relationship between antidepressant prescription rates and rate of early adolescent suicide. Am J Psychiatry 2006; 163:1898-1904
4. Olfson M, Marcus SC, Shaffer D: Antidepressant drug therapy and suicide in severely depressed children and adults: a case-control study. Arch Gen Psychiatry 2006; 63:865-872
5. Bridge JA, Iyengar S, Salary CB, Barbe RP, Birmaher B, Pincus HA, Ren L, Brent DA: Clinical response and risk for reported suicidal ideation and suicide attempts in pediatric antidepressant treatment: a meta-analysis of randomized controlled trials. JAMA 2007; 297:1683-1696
6. Martin A, Young C, Leckman JF, Mukonoweshuro C, Rosenheck R, Leslie D: Age effects on antidepressant-induced manic conversion. Arch Pediatr Adolesc Med 2004; 158:773-780
7. Ansorge MS, Zhou M, Lira A, Hen R, Gingrich JA: Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice. Science 2004; 306:879-881
8. Maciag D, Simpson KL, Coppinger D, Lu Y, Wang Y, Lin RC, Paul IA: Neonatal antidepressant exposure has lasting effects on behavior and serotonin circuitry. Neuropsychopharmacology 2006; 31:47-57
9. 1 receptor stimulation during development. Brain Res 2006; 1125:171-175
10. LaRoche RB, Morgan RE: Adolescent fluoxetine exposure produces enduring, sex-specific alterations of visual discrimination and attention in rats. Neurotoxicol Teratol 2007; 29:96-107
11. Beardslee WR, Wright EJ, Gladstone TRG, Forbes P: Long-term effects from a randomized trial of two public health preventive interventions for parental depression. J Fam Psychol (in press)
12. Brent DA, Oquendo M, Birmaher B, Greenhill L, Kolko D, Stanley B, Zelazny J, Brodsky B, Bridge J, Ellis S, Salazar JO, Mann JJ: Familial pathways to early-onset suicide attempt: risk for suicidal behavior in offspring of mood-disordered suicide attempters. Arch Gen Psychiatry 2002; 59:801-807
13. Linehan MM, Heard HL, Armstrong HE: Naturalistic follow-up of a behavioral treatment for chronically parasuicidal borderline patients. Arch Gen Psychiatry 1993; 50:971-974
14. Linehan MM, Comtois KA, Murray AM, Brown MZ, Gallop RJ, Heard HL, Korslund KE, Tutek DA, Reynolds SK, Lindenboim N: Two-year randomized controlled trial and follow-up of dialectical behavior therapy vs. therapy by experts for suicidal behaviors and borderline personality disorder. Arch Gen Psychiatry 2006; 63:757-766