Possible therapeutic implication of Aβ disturbances in depression [2]

International Journal of Geriatric Psychiatry

Volumn 22, Issue 9, 2007, Pages 931-932

  Pomara, Nunzio ^a   Sidtis, John ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42];

AGED; AGING; BRAIN LEVEL; CHRONIC DISEASE; DEPRESSION; DISEASE SEVERITY; HEALTH STATUS; HUMAN; HYPOTHESIS; LETTER; PROTEIN BLOOD LEVEL; PROTEIN CEREBROSPINAL FLUID LEVEL;

AGE FACTORS; AGED; AMYLOID BETA-PROTEIN; BIOLOGICAL MARKERS; DEPRESSION; HUMANS; MIDDLE AGED; PEPTIDE FRAGMENTS;

EID: 34648816919     PISSN: 08856230     EISSN: 10991166     Source Type: Journal    
DOI: 10.1002/gps.1763     Document Type: Letter

References (7)

1. Aisen PS, Saumier D, Briand R, et al. 2006. A Phase II study targeting amyloid-β with 3APS in mild to moderate Alzheimer's disease. Neurology 67: 1757-1763.
2. Gonzalo-Ruiz A, Gonzalez I, Sanz-Anquela JM. 2003. Effects of β-amyloid protein on serotoninergic, noradrenergic, and cholinergic markers in neurons of the pontomesencephalic tegmentum in the rat. J Chemical Neuroanatomy 26: 153-169.
3. Mehta PD, Pirttila T, Patrick BA, et al. 2001. Amyloid β protein 1-40 and 1-42 levels in matched cerebrospinal fluid and plasma from patients with Alzheimer's disease. Neuroscience 304: 102-106.
4. Meltzer CC, Butters MA, Klunk WE, et al. 2005. Amyloid imaging with Pittsburg Compound-B in late-life depression. Paper presenteds at the Alzheimer's Association International Conference on Prevention of Dementia, Washington, DC.
5. Pomara N, Doraiswamy MP. 2003. Does increased platelet release of Aβ peptide contribute to brain abnormalities in individuals with depression? Medical Hypotheses 60: 640-643.
6. Pomara N, Doraiswamy MP, Willoughby LM, et al. 2006. Elevation in plasma Aβ42 in geriatric depression: a pilot study. Neurochem Res 31: 341-349.
7. Qiu WQ, Sun X, Selkoe DJ, et al. 2006. Depression is associated with low plasma Aβ independently of cardiovascular disease in the homebound elderly. Int J Geriatr Psychiatry (online).