Sequencing of chemotherapy and radiation therapy for early breast cancer

Cochrane Database of Systematic Reviews

Volumn , Issue 4, 2006, Pages

  Hickey, Brigid E ^a   Francis, D ^b   Lehman, M H ^b  

^a Queensland Radium Institute   (Australia)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE; CYCLOPHOSPHAMIDE; DOXORUBICIN; FLUOROURACIL; FOLINIC ACID; METHOTREXATE; MITOXANTRONE; PREDNISONE;

ADJUVANT CHEMOTHERAPY; ALOPECIA; BREAST CANCER; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURVIVAL; CARDIOTOXICITY; COCHRANE LIBRARY; CONFIDENCE INTERVAL; DATA ANALYSIS; DATA EXTRACTION; DISEASE FREE SURVIVAL; ESOPHAGEAL TOXICITY; FEVER; HAZARD RATIO; HEMATOLOGICAL TOXICITY; HUMAN; INFECTION; INFORMATION PROCESSING; LYMPHEDEMA; MULTIPLE CYCLE TREATMENT; NAUSEA AND VOMITING; NEUTROPENIC SEPSIS; NEUTROPHIL TOXICITY; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PLATELET TOXICITY; QUALITY OF LIFE; RANDOMIZATION; REVIEW; SKIN TOXICITY; SUBCUTANEOUS TOXICITY;

EID: 34548864936     PISSN: 1469493X     EISSN: None     Source Type: Journal    
DOI: 10.1002/14651858.CD005212.pub2     Document Type: Review

References (72)

1. Arcangeli G, Pinnaro P, Rambone R, Giannarelli D, Benassi M. A phase III randomised study on the sequencing of radiotherapy and chemotherapy in the conservative management of early-stage breast cancer. International Journal of Radiation Oncology Biology Physics 2006;64(1):161-7.
2. Bellon JR, Come SE, Gelman RS, Henderson IC, Shulman LN, Silver B, et al. Sequencing of chemotherapy and radiation therapy for patients with early stage breast cancer: updated results of a prospective randomized trial. International Journal of Oncology Biology Physics 2001;51(3 Suppl 1):2-3.
3. * Bellon JR, Come SE, Gelman RS, Henderson IC, Shulman LN, Silver B, et al. Sequencing of chemotherapy and radiation therapy in early-stage breast cancer: updated results of a prospective randomized trial. Journal of Clinical Oncology 2005;23(9):1934-40.
4. Hardenbergh PH, Recht A, Gollamudi S, Come SE, Hayes DF, Shulman L, et al. Treatment-related toxicity froma randomized trial of the sequencing of doxorubicin and radiation therapy in patients treated for early stage breast cancer. International Journal of Radiation Oncology Biology Physics 1999;45(1):69-72.
5. Recht A, Come SE, Henderson IC, Gelman RS, Silver B, Hayes DF, et al. Sequencing of chemotherapy and radiotherapy after conservative surgery for early stage breast cancer. New England Journal of Medicine 1996;334(12):1349-55.
6. * Calais G. Radiation and concomitant chemotherapy after surgery for breast cancer. Cancer/Radiothérapie 2004;8:39-47.
7. Calais G. Radiation and concomitant chemotherapy after surgery for breast cancer: Arcosein study [Irradiation et chimiotherapir concomitantes apres chirurgie pur cancer du sein: etude Arcosein]. Cancer/Radiothé rapie 1998;2(5):469-74.
8. Calais G, Berger C, Fourquet A, Bosset JF, Helfre S, Breteau N, et al. of the ACROSEIN group, France. Sequencing radiation therapy (RT) and adjuvant chemotherapy (CT) after conservative surgery for patients with stages I and II breast carcinoma. Preliminary results (acute toxicity and treatment compliance) of a randomized trial comparing RT with concomitant administration of CT versus sequential treatment. Radiotherapy and Oncology 1998;48(Suppl 1):S125.
9. Calais G, Serin D, Fourquet A, Bosset J, Favre A, Oudinot P, et al. Randomized study comparing adjuvant radiotherapy (RT) with concomitant chemotherapy (CT) versus sequential treatment after conservative surgery for patients with stages I and II breast carcinoma. International journal of Radiation Oncology Biology Physics 2002;54(1):57-8.
10. Assersohn L, Powles TJ, Ashley S, Nash AG, Neal AJ, Sacks N, et al. Local relapse in primary breast cancer patients with excised positive surgical margins after lumpectomy, radiotherapy and chemoendocrine therapy. Annals of Oncology 1999;10:1451-5.
11. Bellantone R, Lombardi CP, Cefaro GA, Nardone L, Rossi S, Minelli S, et al. CMF and radiotherapy in the primary treatment of operable breast cancer: preliminary results of a phase II pilot study. Journal of Surgical Oncology 1998;68:48-50.
12. Bellon JR, Come SE, Gelman RS, Li X, Shulman LN, Silver BJ, et al. Concurrent CMF and reduced-dose radiation therapy (RT) in patients with early-stage breast cancer: updated results of a prospective trial. International Journal of Radiation Oncology Biology Physics 2002;54(2 Suppl 1):57.
13. Bellon JR, Shulman LN, Come SE, Li X, Gelman RS, Silver BJ, et al. A prospective study of concurrent cyclophosphamide/methotrexate/5-fluorouracil and reduced-dose radiotherapy in patients with early-stage breast carcinoma. Cancer 2004;100(7):1358-64.
14. Blomqvist C, Tiusanen K, Elomaa I, Rissanen P, Hietanen T, Heinonen E, et al. The combination of radiotherapy, adjuvant chemotherapy cyclophosphamide- doxorubicin-ftorafur) and tamoxifen in stage II breast cancer. Long-term follow-up results of a randomised trial. British Journal of Cancer 1992;66:1171-6.
15. Buzdar AU, Kau SW, Smith TL, Ames F, Singletary E, Strom E, et al. The order of administration of chemotherapy and radiation and its effect on the local control of operable breast cancer. Cancer 1993;71(11):3680- 7.
16. Cakir S, Gursel B, Meydan D, Yildiz L. The sequencing of radiation therapy and chemotherapy after mastectomy in premenopausal women with breast cancer. Japanese Journal of Clinical Oncology 2003;33(11):563-9.
17. Denham JW, Hailton CS, Christie D, O'Brien M, Bonaventura A, Stewart JF, et al. Simultaneous adjuvant radiation therapy and chemotherapy in high-risk breast cancer toxicity and dose modification: a Trans-Tasman Radiation Oncology Group multi-institution study. International Journal of Radiation Oncology Biology Physics 1995;31(2):305-13.
18. Donato V, Monaco A, Messina F, De Sanctis V, Messineo D, Banellis E, et al. Local recurrence in breast cancer after conservative surgery: timing of radiotherapy and sequencing of chemotherapy. Anticancer Research 2004;24(2C):1303-6.
19. Dubey A, Recht A, Come SE, Gelman RS, Silver B, Harris JR, et al. Concurrent CMF and radiation therapy for early stage breast cancer: results of a pilot study. International Journal of Radiation Oncology Biology Physics 1999;45(4):877-84.
20. Faul C, Jacob H, Karasek-Gerszten K, Kunschner A, Vogel V, Flickinger J. Concurrent CMF chemotherapy and radiation therapy in early breast cancer: tolerance and cosmesis (Meeting abstract). Proceedings of the annual meeting of the American Society of Clinical Oncology. 1998.
21. Faul C, Brufsky A, Gerszten K, Flickinger J, Kunschner A, Jacob H, et al. Concurrent sequencing of full-dose CMF chemotherapy and radiation therapy in early breast cancer has no effect on treatment delivery. European Journal of Cancer 2003;39:763-8.
22. Fiets WE, van Helvoirt RP, Nortier JWR, van der Tweel I, Struikmans H. Acute toxicity of concurrent adjuvant radiotherapy and chemotherapy (CMF or AC) in breast cancer patients: a prospective, comparative, non-randomised study. European Journal of Cancer 2003;39:1081-8.
23. Garcia PJL, Talavera HMC, Rodriguez RP, Cueto LDGJ, Martin LI, Moya OJ, et al. Adjuvant QT and RT in breast cancer. Influence of the therapeutic sequence [Irradiacion Y quimioterapia adyuvante en cancer de mama. Influencia de la secuencia terapeutica en el control a largo plazo de la enfermedad]. Oncologia 1996;19(1):52-60.
24. Hartsell WR, Recine DC, Griem KL, Murthy AK. Delaying the initiation of intact breast irradiation for patients with lymph node positive breast cancer increases the risk of local recurrence. Cancer 1995;76(12):2497- 503.
25. Hasbini A, Le Pechoux C, Roche B, Pignol JP, Zelek L, Abdulkarim B, et al. NA [Radiothérapie hyperfractionnée alternée une chimiothérapie dans le cancer du sein inflammatoire non métastatique]. Cancer/Radiothérapie 2000;4:265-73.
26. Isaac N, Panzarella T, Lau A, Mayers C, Kirkbride P, Tannock IF, et al. Concurrent cyclophosphamide, methotrexate, and 5-fluorouracil chemotherapy and radiotherapy for breast carcinoma. Cancer 2002;95(4):696-702.
27. Lamb D, Atkinson C, Joseph D, O'Brien P, Ackland S, Bonaventura A, et al. Simultaneous adjuvant radiotherapy and chemotherapy for stage I and II breast cancer. Australasian Radiology 1999;43:220-6.
28. Leonard CE, Wood ME, Zhen B, Rankin J, Waitz Da, Norton L, et al. Does administration of chemotherapy before radiotherapy in breast cancer patients treated with conservative surgery negatively impact local control?. Journal of Clinical Oncology 1995;13(12):2906-15.
29. Recht A, Come SE, Gelman RS, Goldstein M, Tishler S, Gore SM, et al. Integration of conservative surgery, radiotherapy, and chemotherapy for the treatment of early stage, node positive breast cancer: sequencing, timing and outcome. Journal of Clinical Oncology 1991;9(9):1662-7.
30. Rouesse J, Cvitkovic F, De Lalande B, Serin D, Graic Y, Combe M, et al. Concomitant or sequential chemo-radiotherapy (CRT) in operable breast cancer. Final results of a French multicentric phase III study. Breast Cancer Research and Treatment 2002;76(Suppl 1):S160.
31. Rubens RD, Sexton S, Tong D, Winter PJ, Knight RK, Hayward JL. Combined chemotherapy and radiotherapy for locally advanced breast cancer. European Journal of Cancer 1980;16:351-6.
32. Sauer R, Martus D. Sequencing of chemotherapy and radiotherapy following breast-preserving treatment of breast carcinoma. Strahlentherapie und Onkologie 1996;172(9):516-7.
33. Stemmer SM, Rizel S, Hardan I, Adamo A, Neumann A, Goffman J, et al. The role of irradiation of the internal mammary lymph nodes in high risk stage II to IIIa breast cancer patients after high-dose chemotherapy: a prospective sequential non-randomized study. Journal of Clinical Oncology 2003;21(14):2713-8.
34. Wallgren A, Bernier J, Gelber RD, Goldhirsch A, Ronacadin M, Joseph D, et al. for the International Breast Cancer Study Group. Timing of radiotherapy and chemotherapy following breast-conserving surgery for patients with node-positive breast cancer. International Journal of Radiation Oncology Biology Physics 1996;35(4):649-9.
35. Warner NJ, Rangan AM, Langlands AO, Boyages J. Effect of concurrently chemotherapy and radiotherapy on breast cosmesis: a study of patients' perceptions. The Breast 1998;7:131-6.
36. Zambetti M, Oriana S, Quattrone P, Verderio P, Terenziana M, Zucali R, et al. Combined sequential approach in locally advanced breast cancer. Annals of Oncology 1999;10:305-10.
37. Fernando I. Phase III randomised study of synchronous versus sequential adjuvant chemotherapy and radiotherapy in women with early stage breast cancer. PDQ 1999.
38. Altman DG. Practical statistics for medical research. London: Chapman and Hall, 1992.
39. Ash DV. Waiting times for cancer treatment [editorial]. Clinical Oncology (Royal College of Radiologists) 2000;12(140):3.
40. Bellon JR, Come SE, Gelman RS, Henderson IC, Shulman LN, Silver B, et al. Sequencing of chemotherapy and radiotherapy for patients with early stage breast cancer: updated results of a prospective randomized trial [abstract]. International Journal of Radiation Oncology Biology Physics 2001;51Suppl 3(2a):2-3.
41. Buchholz TA, Austin-Seymour MM, Moe RE, Ellis GK, Livingston RB, Pelton JG, et al. Effect of delay in radiation in the combined modality treatment of breast cancer. International Journal of Radiation Oncology Biology Physics 1993;26(1):23-35.
42. Buchholz TA, Hunt KK, Amosson CM, Tucker SL, Strom EA, McNeese MD, et al. Sequencing of chemotherapy and radiation in lymph node-negative breast cancer. Cancer Journal from Scientific American 1999;5(3):159-64.
43. Calais G, Berger C, Fourquet A, Bosset JF, Helfre S, Breteau N, et al of the ACROSEIN group, France. Sequencing radiation therapy (RT) and adjuvant chemotherapy (CT) after conservative surgery for patients with stages I and II breast carcinoma. Preliminary results (acute toxicity and treatment compliance) of a randomized trial comparing RT with concomitant administration of CT versus sequential treatment. Radiotherapy and Oncology 1998;48 Suppl 1:S125.
44. Calais G. Radiation and concomitant chemotherapy after surgery for breast cancer: Arcosein study [Irradiation et chimiotherapir concomitantes apres chirurgie pur cancer du sein: etude Arcosein]. Cancer/Radiothé rapie 1998;2(5):469-74.
45. Calais G, Serin D, Fourquet A, Bosset J, Favre A, Oudinot P, et al. Randomized study comparing adjuvant radiotherapy (RT) with concomitant chemotherapy (CT) versus sequential treatment after conservative surgery for patients with stages I and II breast carcinoma. International Journal of Radiation Oncology Biology Physics 2002;54(1 Suppl 1):57-58.
46. Churn M, Kelly V. Outpatient follow-up after treatment for early breast cancer: updated results after 5 years. Clinical Oncology (Royal College of Radiologists) 2001;13(3):187-94.
47. Deeks JJ, Higgins, JPT, Altman DG, editors. Analysing and presenting results. In: AldersonP, GreenS, HigginsJPT editor(s). Cochrane Reviewers' Handbook 4.2.2 [updated December 2003]; Section 8. The Cochrane Library, Issue 1, 2004. Chichester, UK: John Wiley & Sons Ltd, 2003.
48. Early Breast Cancer Trialists Collaborative Group. Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials. Lancet 2005;366:2087-106.
49. Early Breast Cancer Trialists Collaborative Group. Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet 2005;365:1687-717.
50. Formenti SC, Volm M, Skinner KA, Spicer D, Cohen D, Perez E, et al. Preoperative twice-weekly paclitaxel with concurrent radiation therapy followed by surgery and postoperative doxorubicin-based chemotherapy in locally advanced breast cancer: a phase I/II trial. Journal of Clinical Oncology 2003;21(5):861-70.
51. Greenland S, Robbins J. Estimation of a common effect parameter from sparse follow-up data. Biometrics 1985;48:159-63.
52. Hardenbergh PH, Recht A, Gollamudi S, Come SE, Hayes DF, Shulman L, et al. Treatment-related toxicity froma randomized trial of the sequencing of doxorubicin and radiation therapy in patients treated for early stage breast cancer. International Journal of Radiation Oncology Biology Physics 1999;45(1):69-72.
53. Henderson IC, Berry DA, Demetri GD, Cirrincione CT, Goldstein LJ, Martino S. Improved outcomes fromadding sequential paclitaxel but not from escalating doxorubicin dose in an adjuvant chemotherapy regimen for patients with node-positive primary breast cancer. Journal of Clinical Oncology 2003;21(6):976-83.
54. Huang J, Barbera L, Brouwers M, Browman G, Mackillop WJ. Does delay in starting treatment affect the outcomes of radiation therapy? A systematic review. Journal of Clinical Oncology 2002;21(3):555-63.
55. Kenny L, Lehman M. Sequential audit of unacceptable delays in radiation therapy in Australia and New Zealand. Australasian Radiology 2004;48(1):29-34.
56. Kurtz JM, Amalric R, Delouche G, Pierquin B, Roth J, Spitalier JM. The second ten years: long-term risks of breast conservation in early breast cancer. International Journal of Radiation Oncology Biology and Physics 1987;13(9):1327-32.
57. Leong C, Boyages J, Jayasinghe UW, Bilous M, Ung O, Chua B, et al. Effect of margins on ipsilateral breast tumor recurrence after breast conservation therapy for lymph node-negative breast carcinoma. Cancer 2004;100(9):1823-32.
58. Lippman ME. How should we manage breast cancer in the breast, or buddy, a new paradigm?. Journal National Cancer Institute 1995;87(1):3-4.
59. MacKillop WJ, Fu HU, Quirt CF, Dixon P, Brundage M, Zhou, Y. Waiting for radiation therapy in Ontario. International Journal of Radiation Oncology Biology Physics 1994;30(1):221-8.
60. MacKillop WJ, Quirt CF. A comparison of delays in treatment of cancer with radiation therapy in Canada and the United States. International Journal of Radiation Oncology Biology Physics 1995;32(2):531-9.
61. Macquart-Moulin G, Viens P, Genre D, Bouscary ML, Resbeut M, Gravis G, et al. Concomitant chemoradiotherapy for patients with nonmetastatic breast carcinoma: side effects, quality of life, and organization. Cancer 1999;85(10):2190-9.
62. Mantel N, Haenszel WH. Statistical aspects of the analysis of data for retrospective studies of disease. Journal of the National Cancer Institute 1959;22:719-48.
63. Martin M, Pienkowski T, Mackey J, Pawlicki M, Guastalla JP, Weaver C, et al. Adjuvant docetaxel for node-positive breast cancer. New England Journal of Medicine 2005;352(22):2302-13.
64. McCormick B, Norton L, Yao TJ, Yahalom J, Petrek JA. The impact of the sequence of radiation and chemotherapy on local control after breast-conserving surgery. Cancer Journal from Scientific American 1996;2(1):39.
65. Meek AG, Park TL, Weiss TA, Bethune WA. Effect of delayed radiation therapy on local control in breast conservation therapy. Radiology 1996;200(3):615-9.
66. Olivotto IA, Chua B, Elliott EA, Parda DS, Pierce LJ, Shepherd L, et al. A clinical trial of breast radiation therapy versus breast plus regional radiation therapy in early-stage breast cancer: the MA20 trial. Clinical Breast Cancer 2003;4(5):361-3.
67. Ragaz J, Olivetto I, Spinelli J, Phillips N, Jackson S, Wilson K, et al. Locoregional radiation therapy in patients with high risk breast cancer receiving adjuvant chemotherapy: 20-year results of the British Columbia randomised trial. Journal of the National Cancer Institute 2005;97(2):116-26.
68. Recht A, Come SE, Henderson IC, Gelman RS, Silver B, Hayes DF, et al. Sequencing of chemotherapy and radiotherapy after conservative surgery for early stage breast cancer. New England Journal of Medicine 1996;334(12):1349-55.
69. Slotman BJ, Meyer OW, Njo KH, Karim AB. Importance of timing of radiotherapy in breast conserving treatment for early stage breast cancer. Radiotherapy and Oncology 1994;30(3):206-12.
70. Taghian AG, Assaad SI, Niemierko A, Kuter I, Younger J, Schoenthaler R, et al. Risk of pneumonitis in breast cancer patients treated with radiation therapy and combination chemotherapy with paclitaxel. Journal of the National Cancer Institute 2001;93(23):1806-11.
71. Walker AM, Martin-Moreno JM, Artalejo FR. Odd man out: a graphical approach to meta-analysis. American Journal of Public Health 1988;78:961-6.
72. Whelan T, MacKenzie R, Julian J, Levine M, Shelley W, Grimard L, et al. Randomized trial of breast irradiation schedules after lumpectomy for women with lymph node-negative breast cancer. Journal National Cancer Institute 2002;94(15):1143-50.