Expression of dendritic cell markers on cultured neutrophils and its modulation by anti-apoptotic and pro-apoptotic compounds

Experimental and Molecular Medicine

Volumn 39, Issue 4, 2007, Pages 439-449

  Park, Hae Young ^a   Jin, Jun O ^a   Song, Min Gyu ^a   Park, Joo In ^a   Kwak, Jong Young ^a  

^a Dong A University   (South Korea)

Author keywords

Antigen presenting cells; Antigens, CD95; Apoptosis; Dendritic cells; Neutrophils

Indexed keywords

B7 ANTIGEN; CD40 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; GAMMA INTERFERON; LIPOCORTIN 5; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MESSENGER RNA;

ANTIGEN PRESENTING CELL; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DENDRITIC CELL; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERFERON PRODUCTION; NEUTROPHIL; PROTEIN EXPRESSION;

EID: 34548858170     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2007.48     Document Type: Article

References (37)

1. Aleman M, de la Barrera SS, Schierloh PL, Alves L, Yokobori N, Baldini M, Abbate E, Sasiain MC. In tuberculous pleural effusions, activated neutrophils undergo apoptosis and acquire a dendritic cell-like phenotype. J Infect Dis 2005;192:399-409
2. Bliss SK, Butcher BA, Denkers EY. Rapid recruitment of neutrophils containing prestored IL-12 during microbial infection. J Immunol 2000;165:4515-21
3. Burg ND, Pillinger MH. The neutrophil: function and regulation in innate and humoral immunity. Clin Immunol 2001;99:7-17
4. Clayton AR, Prue RL, Harper L, Drayson MT, Savage CO. Dendritic cell uptake of human apoptotic and necrotic neutrophils inhibits CD40, CD80, and CD86 expression and reduces allogeneic T cell responses: relevance to systemic vasculitis. Arthritis Rheum 2003;48:2362-74
5. de Carvalho Bittencourt M, Saas P, Fresnay S, Yerly-Motta V, Ferrand C, Perruche S, Duperrier A, Herve P, Tiberghien P, Chalmers DE. Exposure to exogenous DNA can modify the sensitivity of the Fas apoptotic pathway. J Gene Med 2002;4:14-24
6. Dransfield I, Buckle AM, Savill JS, McDowall A, Haslett C, Hogg N. Neutrophil apoptosis is associated with a reduction in CD16 (FcγRIII) expression. J Immunol 1994;153:1254-63
7. Fanger NA, Liu C, Guyre PM, Wardwell K, O'Neil J, Guo TL, Christian TP, Mudzinski SP, Gosselin EJ. Activation of human T cells by major histocompatability complex class II expressing neutrophils: proliferation in the presence of superantigen, but not tetanus toxoid. Blood 1997;89:4128-35
8. Iking-Konert C, Cseko C, Wagner C, Stegmaier S, Andrassy K, Hansch GM. Transdifferentiation polymorphonuclear neutrophils: acquisition of CD83 and other functional characteristics of dendritic cells. J Mol Med 2001a;79:464-74
9. Iking-Konert C, Vogt S, Radsak M, Wagner C, Hansch GM, Andrassy K. Polymorphonuclear neutrophils in Wegener's granulomatosis acquire characteristics of antigen presenting cells. Kidney Int 2001b;60:2247-62
10. Iking-Konert C, Wagner C, Denefleh B, Hug F, Schneider M, Andrassy K, Hansch GM. Up-regulation of the dendritic cell marker CD83 on polymorphonuclear neutrophils (PMN): divergent expression in acute bacterial infections and chronic inflammatory disease. Clin Exp Immunol 2002;130:501-8
11. Kim KD, Choi SC, Noh YW, Kim JW, Paik SG, Yang Y, Kim K 2nd, Lim JS. Impaired responses of leukemic dendritic cells derived from a human myeloid cell line to LPS stimulation. Exp Mol Med 2006;38:72-84
12. Kobayashi SD, Voyich JM, Braughton KR, DeLeo FR. Down-regulation of proinflammatory capacity during apoptosis in human polymorphonuclear leukocytes. J Immunol 2003;170:3357-68
13. Kuchroo VK, Das MP, Brown JA, Ranger AM, Zamvil SS, Sobel RA, Weiner HL, Nabavi N, Glimcher LH. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. Cell 1995;80:707-18
14. Lee MJ, Park JY, Lee SY, Lee JS, Jung DK, Bae YS, Kwak JY. Modulation of constitutive and delayed apoptosis by brefeldin A in human neutrophils. Int Immunopharmacol 2003;3:835-43
15. Lee SY, Oh JY, Lee MJ, Jang MJ, Park HY, Kim JW, Min DS, Park YM, Chang YC, Bae YS, Kwak JY. Anti-apoptotic mechanism and reduced expression of phospholipase D in spontaneous and Fas-stimulated apoptosis of human neutrophils. Eur J Immunol 2004;34:2760-70
16. + myeloid cells inhibit development of antifungal Th1 immunity in mice with candidiasis. J Immunol 2002;169:3180-90
17. Oehler L, Majdic O, Pickl WF, Stockl J, Riedl E, Drach J, Rappersberger K, Geissler K, Knapp W. Neutrophil granulocyte-committed cells can be driven to acquire dendritic cell characteristics. J Exp Med 1998;187:1019-28
18. Park HW, Park OJ, Shin JE, Choi YN. Receptor activator of NF-κB ligand enhances the activity of macrophages as antigen presenting cells. Exp Mol Med 2005;37:524-32
19. Park MA, Lee MJ, Lee SH, Jung DK, Kwak JY. Anti-apoptotic role of phospholipase D in spontaneous and delayed apoptosis of human neutrophils. FEBS Lett 2002;519:45-9
20. Radsak M, Iking-Konert C, Stegmaier S, Andrassy K, Hansch GM. Polymorphonuclear neutrophils as accessory cells for T-cell activation: major histocompatibility complex class II restricted antigen-dependent induction of T-cell proliferation. Immunology 2000;101:521-30
21. Randolph GJ, Beaulieu S, Lebecque S, Steinman RM, Muller WA. Differentiation of monocytes into dendritic cells in a model of transendothelial trafficking. Science 1998;282:480-3
22. Savill J. Apoptosis in resolution of inflammation. J Leukoc Biol 1997;61:375-80
23. Sethna MP, van Parijs L, Sharpe AH, Abbas AK, Freeman GJ. A negative regulatory function of B7 revealed in B7-1 transgenic mice. Immunity 1994;1:415-21
24. Suzuki M, Shinohara F, Sato K, Taniguchi T, Takada H, Rikiishi H. Interleukin-1β converting enzyme subfamily inhibitors prevent induction of CD86 molecules by butyrate through a CREB-dependent mechanism in HL60 cells. Immunology 2003;108:375-83
25. Tateda K, Moore TA, Deng JC, Newstead MW, Zeng X, Matsukawa A, Swanson MS, Yamaguchi K, Standiford TJ. Early recruitment of neutrophils determines subsequent T1/T2 host responses in a murine model of Legionella pneumophila pneumonia. J Immunol 2001;166:3355-61
26. Taub DD, Anver M, Oppenheim JJ, Longo DL, Murphy WJ. T lymphocyte recruitment by interleukin-8 (IL-8). IL-8-induced degranulation of neutrophils releases potent chemoattractants for human T lymphocytes both in vitro and in vivo. J Clin Invest 1996;97:1931-41
27. van Gisbergen KP, Geijtenbeek TB, van Kooyk Y. Close encounters of neutrophils and DCs. Trends Immunol 2005;26:626-31
28. Vella A, Sartoris S, Bambara L, Ortolani R, Carletto A, Biasi D, Stefani E, Tridente G. Cell contact-dependent PMN HLA-DR and CD69 membrane expression induced by autologous mono-lymphocytes and cell lines. Inflammation 2002;26:143-52
29. Ward C, Chilvers ER, Lawson MF, Pryde JG, Fujihara S, Farrow SN, Haslett C, Rossi AG. NF-κB activation is a critical regulator of human granulocyte apoptosis in vitro. J Biol Chem 1999a;274:4309-18
30. Ward C, Dransfield L, Chilvers ER, Haslett I, Rossi AG. Pharmacological manipulation of granulocyte apoptosis: potential therapeutic targets. Trends Pharmacol Sci 1999b;20:503-9
31. Watson RW, Rotstein OD, Jimenez M, Parodo J, Marshall JC. Augmented intracellular glutathione inhibits Fas-triggered apoptosis of activated human neutrophils. Blood 1997;89:4175-81
32. Watson RW, O'Neill A, Brannigen AE, Coffey R, Marshall JC, Brady HR, Fitzpatrick JM. Regulation of Fas antibody induced neutrophil apoptosis is both caspase and mitochondrial dependent. FEBS Lett 1999;453:67-71
33. Whyte MKB, Meagher LC, MacDermot J, Haslett C. Impairment of function in aging neutrophils is associated with apoptosis. J Immunol 1993;150:5124-34
34. Windhagen A, Maniak S, Gebert A, Ferger L, Wurster U, Heidenreich F. Human polymorphonuclear neutrophils express a B7-1-like molecule. J Leukoc Biol 1999;66:945-52
35. Yamashiro S, Wang JM, Yang D, Gong WH, Kamohara H, Yoshimura T. Expression of CCR6 and CD83 by cytokine-activated human neutrophils. Blood 2000;96:3958-63
36. Yoshimura S, Bondeson J, Foxwell BM, Brennan FM, Feldmann M. Effective antigen presentation by dendritic cells is NF-κB dependent: coordinate regulation of MHC, co-stimulatory molecules and cytokines. Int Immunol 2001;13:675-83
37. Zhao J, Freeman GJ, Gray GS, Nadler LM, Glimcher LH. A cell type-specific enhancer in the human B7.1 gene regulated by NF-κB. J Exp Med 1996;183:777-89