A 28-day oral (dietary) toxicity study of sucromalt in Sprague-Dawley rats

Food and Chemical Toxicology

Volumn 45, Issue 11, 2007, Pages 2304-2311

  Eapen, Alex K ^a   Chengelis, Christopher P ^a   Jordan, Nancy P ^a   Baumgartner, Roxanne E ^c   Zheng, Guo Hua ^b   Carlson, Ting ^b  

^a WIL RESEARCH LABORATORIES   (United States)

^b CARGILL INC   (United States)

^c Vet Path Services Inc   (United States)

Author keywords

Dietary; Sprague Dawley; Sucromalt

Indexed keywords

FRUCTOSE; GLUCOSE; LEUCROSE; MALTOSE; OLIGOSACCHARIDE; SUCROMALT; SUCROSE; SWEETENING AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EATING HABIT; EVALUATION; FEMALE; FOOD INTAKE; FOOD SAFETY; MALE; NONHUMAN; RAT; SPRAGUE DAWLEY RAT; TOXICITY TESTING; WEIGHT GAIN;

ANIMALS; BEHAVIOR, ANIMAL; BODY WEIGHT; DIET; DISACCHARIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; EYE; FEMALE; FRUCTOSE; MALE; MOTOR ACTIVITY; OLIGOSACCHARIDES; RATS; RATS, SPRAGUE-DAWLEY; SWEETENING AGENTS; TIME FACTORS;

RATTUS;

EID: 34548858155     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2007.06.008     Document Type: Article

References (14)

1. Dunnett C.W. New tables for multiple comparisons with a control. Biometrics 20 (1964) 482-491
2. Eapen, A.E. (Principal Investigator), 2004. A 7-day dietary range-finding study of sucromalt in rats. Ashland, OH: WIL Research Laboratories, Inc. Report No. WIL-492001. 223 p.
3. Gad S.C. A neuromuscular screen for use in industrial toxicology. Journal of Toxicology and Environmental Health 9 (1982) 691-704
4. Haggerty G.C. Development of tier I neurobehavioral testing capabilities for incorporation into pivotal rodent safety assessment studies. Journal of the American College of Toxicology 8 1 (1989) 53-69
5. Irwin S.C. Comprehensive observational assessment: Ia. A systematic quantitative procedure for assessing the behavioral physiological state of the mouse. Psychopharmacologia 13 (1968) 222-256
6. In: Luna L.G. (Ed). American Registry of Pathology. third ed. Manual of Histologic Staining Methods of the Armed Forces Institute of Pathology (1968), McGraw-Hill Book Co, New York, NY 38-39
7. Moser V.C., McCormick J.P., Creason J.P., and MacPhail R.C. Comparison of chlordimeform and carbaryl using a functional observational battery. Fundamental and Applied Toxicology 11 (1988) 189-206
8. Moser V.C., McDaniel K.L., and Phillips P.M. Rat strain and stock comparisons using a functional observational battery: baseline values and effects of Amitraz. Toxicology and Applied Pharmacology 108 (1991) 267-283
9. National Research Council. Guide for the care and use of laboratory animals. Institute of Laboratory Animal Resources, Commission on Life Sciences (1996), National Academy Press, Washington, DC 125 p
10. O'Donoghue J.L. Screening for neurotoxicity using a neurologically based examination and neuropathology. Journal of the American College of Toxicology 8 1 (1989) 97-115
11. Snedecor G.W., and Cochran W.G. One way classifications; analysis of variance. Statistical Methods. 7th ed. (1980), The Iowa State University Press, Ames, IA pp. 215-237
12. Steel R.G.D., and Torrie J.H. Principles and procedures of statistics, a biometrical approach. second ed. (1980), McGraw-Hill Book Company, New York, NY pp. 504-506
13. Thompson S.W. Tissue processing and embedding. Selected Histochemical and Histopathological Methods (1966), Charles C. Thomas, Springfield, IL 29-37
14. Young J.T. Histopathological examination of the rat nasal cavity. Fundamental and Applied Toxicology 1 (1981) 309-312