A new method for determining positions of phenolic hydroxyl groups through silylation and application of H(Si)C triple-resonance NMR experiments

Tetrahedron Letters

Volumn 48, Issue 43, 2007, Pages 7586-7590

  Maloň, Michal ^a   Takahashi, Shunya ^a   Koshino, Hiroyuki ^a  

^a INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

Author keywords

29Si 13C long range coupling; 29Si 1H long range coupling; Double INEPT; Phenol

Indexed keywords

CARBON; HYDROGEN; HYDROXYL GROUP; PHENOLIC HYDROXYL; SILICON; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRESS; NUCLEAR MAGNETIC RESONANCE; SILYLATION; SYNTHESIS;

EID: 34548851694     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2007.08.111     Document Type: Article

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35. a).
36. b).
37. 29Si 0.0 ppm). Sample amounts were 10-50 mg.
38. The parameter was set according to the estimated average coupling constant value.
39. 13C frequencies was covered, all carbon signals were readily observed. The pulse sequence and the spectrum are shown in Supplementary data.
40. 29Si HMBC. The triple-resonance experiment is complementary to the NOE experiment that uses through space interactions. The pulse sequence and the resultant H(C)Si spectrum are supplied in Supplementary data.