Lack of evidence for association of Parkin promoter polymorphism (PRKN-258) with increased risk of Parkinson's disease

Parkinsonism and Related Disorders

Volumn 13, Issue 7, 2007, Pages 386-388

  Ross, Owen A ^a   Haugarvoll, Kristoffer ^a,b   Stone, Jeremy T ^a   Heckman, Michael G ^a   White, Linda R ^b   Aasly, Jan O ^b,c   Mark Gibson, J ^d   Lynch, Timothy ^e   Wszolek, Zbigniew K ^f   Uitti, Ryan J ^f   Farrer, Matthew J ^a  

^a Morris K Udall Parkinson's Disease Research Center of Excellence   (United States)

^b NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^c TRONDHEIM UNIVERSITY HOSPITAL   (Norway)

^d ROYAL VICTORIA HOSPITAL   (United Kingdom)

^e MATER MISERICORDIAE UNIVERSITY HOSPITAL   (Ireland)

^f MAYO CLINIC   (United States)

Author keywords

Parkin; Parkinson's disease; Promoter SNP

Indexed keywords

PARKIN;

ADULT; AGED; ARTICLE; CAUCASIAN; CONTROLLED STUDY; GENE EXPRESSION; GENE MUTATION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC TRANSCRIPTION; HUMAN; IRELAND; MAJOR CLINICAL STUDY; NORWAY; PARKINSON DISEASE; PRIORITY JOURNAL; PROMOTER REGION; SINGLE NUCLEOTIDE POLYMORPHISM; UNITED STATES;

ADULT; AGED; AGED, 80 AND OVER; DNA MUTATIONAL ANALYSIS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; IRELAND; MALE; MIDDLE AGED; NORWAY; PARKINSON DISEASE; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); RISK; UBIQUITIN-PROTEIN LIGASES; UNITED STATES;

EID: 34548844714     PISSN: 13538020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.parkreldis.2007.01.010     Document Type: Article

References (16)

1. Kitada T., Asakawa S., Hattori N., Matsumine H., Yamamura Y., Minoshima S., et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392 (1998) 605-608
2. Mata I.F., Lockhart P.J., and Farrer M.J. Parkin genetics: one model for Parkinson's disease. Hum Mol Genet 13 Special Issue, 1 (2004) R127-R133
3. Shimura H., Hattori N., Kubo S., Mizuno Y., Asakawa S., Minoshima S., et al. Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nat Genet 25 (2000) 302-305
4. Gosal D., Ross O.A., and Toft M. Parkinson's disease: the genetics of a heterogeneous disorder. Eur J Neurol 13 (2006) 616-627
5. Lucking C.B., Durr A., Bonifati V., Vaughan J., De Michele G., Gasser T., et al. Association between early-onset Parkinson's disease and mutations in the parkin gene. N Engl J Med 342 (2000) 1560-1567
6. West A., Periquet M., Lincoln S., Lucking C.B., Nicholl D., Bonifati V., et al. Complex relationship between Parkin mutations and Parkinson disease. Am J Med Genet 114 (2002) 584-591
7. Klein C., Hedrich K., Wellenbrock C., Kann M., Harris J., Marder K., et al. Frequency of parkin mutations in late-onset Parkinson's disease. Ann Neurol 54 (2003) 415-416 [author reply 416-7]
8. Lucking C.B., Chesneau V., Lohmann E., Verpillat P., Dulac C., Bonnet A.M., et al. Coding polymorphisms in the parkin gene and susceptibility to Parkinson disease. Arch Neurol 60 (2003) 1253-1256
9. Mata I.F., Alvarez V., Garcia-Moreira V., Guisasola L.M., Ribacoba R., Salvador C., et al. Single-nucleotide polymorphisms in the promoter region of the PARKIN gene and Parkinson's disease. Neurosci Lett 329 (2002) 149-152
10. Oliveira S.A., Scott W.K., Nance M.A., Watts R.L., Hubble J.P., Koller W.C., et al. Association study of Parkin gene polymorphisms with idiopathic Parkinson disease. Arch Neurol 60 (2003) 975-980
11. Wang M., Hattori N., Matsumine H., Kobayashi T., Yoshino H., Morioka A., et al. Polymorphism in the parkin gene in sporadic Parkinson's disease. Ann Neurol 45 (1999) 655-658
12. West A.B., Maraganore D., Crook J., Lesnick T., Lockhart P.J., Wilkes K.M., et al. Functional association of the parkin gene promoter with idiopathic Parkinson's disease. Hum Mol Genet 11 (2002) 2787-2792
13. Tan E.K., Puong K.Y., Chan D.K., Yew K., Fook-Chong S., Shen H., et al. Impaired transcriptional upregulation of Parkin promoter variant under oxidative stress and proteasomal inhibition: clinical association. Hum Genet 118 (2005) 484-488
14. Gelb D.J., Oliver E., and Gilman S. Diagnostic criteria for Parkinson disease. Arch Neurol 56 (1999) 33-39
15. Barrett J.C., Fry B., Maller J., and Daly M.J. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21 (2005) 263-265
16. Lesage S, Magali P, Lohmann E, Lacomblez L, Teive H, Janin S, et al. Deletion of the parkin and PACRG gene promoter in early-onset parkinsonism. Hum Mutat 2007; 28: 27-32.