Whole-body imaging of bacterial infection and antibiotic response

Nature Protocols

Volumn 1, Issue 6, 2007, Pages 2988-2994

  Hoffman, Robert M ^a,b   Zhao, Ming ^a  

^a ANTICANCER INC   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; DIAGNOSTIC AGENT; GREEN FLUORESCENT PROTEIN;

ANIMAL; ARTICLE; BACTERIAL INFECTION; BACTERIUM TRANSFORMATION; ESCHERICHIA COLI; METHODOLOGY; PATHOLOGY; WHOLE BODY IMAGING;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; ESCHERICHIA COLI; GREEN FLUORESCENT PROTEINS; TRANSFORMATION, BACTERIAL; WHOLE BODY IMAGING;

EID: 34548841071     PISSN: 17542189     EISSN: 17502799     Source Type: Journal    
DOI: 10.1038/nprot.2006.376     Document Type: Article

References (6)

1. Zhao, M. et al. Spatial-temporal imaging of bacterial infection and antibiotic response in intact animals. Proc. Natl. Acad. Sci. USA 98, 9814-9818 (2001).
2. Yu, Y.A. et al. Visualization of tumors and metastases in live animals with bacteria and vaccinia virus encoding light-emitting proteins. Nature Biotech. 22, 313-320 (2004).
3. Hoffman, R.M. & Yang, M. Color-coded imaging of tumor-host interaction. Nat. Protocols 1, 928-935 (2006).
4. Hoffman, R.M. The multiple uses of fluorescent proteins to visualize cancer in vivo. Nature Rev. Cancer 5, 796-806 (2005).
5. Zhao, M. et al. Tumor-targeting bacterial therapy with amino acid auxotrophs of GFP-expressing Salmonella typhimurium. Proc. Natl Acad. Sci USA 102, 755-760 (2005).
6. Zhao, M. et al. Targeted therapy with a Salmonella typhimurium leucinearginine auxotroph cures orthotopic human breast tumors in nude mice. Cancer Res. 66, 7647-7652 (2006).