Imidazopiperidine amides as dipeptidyl peptidase IV inhibitors for the treatment of diabetes

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 21, 2007, Pages 5853-5857

  Chen, Ping ^a   Caldwell, Charles G ^a   Mathvink, Robert J ^a   Leiting, Barbara ^a   Marsilio, Frank ^a   Patel, Reshma A ^a   Wu, Joseph K ^a   He, Huaibing ^a   Lyons, Kathryn A ^a   Thornberry, Nancy A ^a   Weber, Ann E ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Diabetes; Dipeptidyl peptidase IV inhibitors; Glucagon like peptide 1 (GLP 1); Imidazopiperidine amides; Incretin hormones

Indexed keywords

DIPEPTIDYL PEPTIDASE IV INHIBITOR; PIPERIDINE DERIVATIVE; SITAGLIPTIN;

ARTICLE; DIABETES MELLITUS; DRUG SELECTIVITY; DRUG STRUCTURE; ENZYME INHIBITION; IC 50;

AMIDES; ANTIGENS, CD26; DIABETES MELLITUS; HUMANS; HYPOGLYCEMIC AGENTS; PIPERIDINES; PROTEASE INHIBITORS;

EID: 34548833898     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.08.030     Document Type: Article

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