Clear cell (glycogen rich) gastric adenocarcinoma: A distinct tubulo-papillary variant with a predilection for the cardia/gastro-oesophageal region

Pathology

Volumn 39, Issue 5, 2007, Pages 466-469

  Ghotli, Zohreh Afshar ^a   Serra, Stefano ^a   Chetty, Runjan ^a,b  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b TORONTO GENERAL HOSPITAL   (Canada)

Author keywords

Clear cells; Gastric cancer; Gastro oesophageal junction; Tubulo papillary pattern

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; CYCLIN D1; CYTOKERATIN 20; CYTOKERATIN 7; HYALIN; TRANSCRIPTION FACTOR CDX2; UVOMORULIN;

ADULT; AGED; ARTICLE; CANCER DIAGNOSIS; CARDIA; CLEAR CELL CARCINOMA; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LOWER ESOPHAGUS SPHINCTER; LYMPH NODE; LYMPH NODE METASTASIS; MALE; PATHOLOGY; PYLORUS; STOMACH CARCINOMA;

ADENOCARCINOMA, CLEAR CELL; AGED; AGED, 80 AND OVER; CARDIA; ESOPHAGOGASTRIC JUNCTION; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; STOMACH NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 34548833344     PISSN: 00313025     EISSN: 14653931     Source Type: Journal    
DOI: 10.1080/00313020701569972     Document Type: Article

References (16)

1. Ishikura H, Kirimoto K, Shamoto M, et al. Hepatoid adenocarcinomas of the stomach. An analysis of seven cases. Cancer 1986; 58: 119-26.
2. Takubo K, Honma N, Sawabe M, et al. Oncocytic adenocarcinoma of the stomach: parietal cell carcinoma. Am J Surg Pathol 2002; 26: 458-65.
3. Luk IS, Bhuta S, Lewin KJ. Clear cell carcinoid tumor of stomach. A variant mimicking gastric xanthelasma. Arch Pathol Lab Med 1997; 121: 1100-3.
4. Ordonez NG, Mackay B, el-Naggar A, Bannayan GA, Duncan J. Clear cell carcinoid tumour of the stomach. Histopathology 1993; 22: 190-3.
5. Govender D, Ramdial PK, Clarke B, Chetty R. Clear cell (glycogen-rich) gastric adenocarcinoma. Ann Diagn Pathol 2004; 8: 69-73.
6. Matsunou H, Konishi F, Jalal RE, Yamamichi N, Mukawa A. Alpha-fetoprotein-producing gastric carcinoma with enteroblastic differentiation. Cancer 1994; 73: 534-40.
7. Jewell LD, Barr JR, McCaughey WT, Nguyen GK, Owen DA. Clear-cell epithelial neoplasms of the large intestine. Arch Pathol Lab Med 1988; 112: 197-9.
8. Vardaman C, Albores-Saavedra J. Clear cell carcinomas of the gallbladder and extrahepatic bile ducts. Am J Surg Pathol 1995; 19: 91-9.
9. Fenoglio-Preiser C, Carneiro F, Correa P. Gastric carcinoma. In: Hamilton SR, Aaltonen LA, editors. World Health Organization Classification of Tumours. Pathology and Genetics: Tumours of the Digestive System. IARC: Lyon, 2002: 38-67.
10. Marsman WA, Tytgat GN, ten Kate FJ, van Lanschot JJ. Differences and similarities of adenocarcinomas of the esophagus and esophagogastric junction. J Surg Oncol 2005; 92: 160-8.
11. Blot JW, Devesa SS, Kneller RW, Fraumeni JF Jr. Rising incidence of adenocarcinoma of the esophagus and gastric cardia. J Am Med Assoc 1991; 265: 1287-9.
12. Siewert JR, Feith M, Stein HJ. Biologic and clinical variations of adenocarcinoma at the esophago-gastric junction: relevance of a topographic-anatomic subclassification. J Surg Oncol 2005; 90: 139-46.
13. Dolan K, Morris AI, Gosney JR, Field JK, Sutton R. Three different subsite classification systems for carcinomas in the proximity of the GEJ, but is it all one disease? J Gastroenterol Hepatol 2004; 19: 24-30.
14. Motoyama T, Aizawa K, Watanabe H, Fukase M, Saito K. Alpha-fetoprotein producing gastric carcinomas: a comparative study of three different subtypes. Acta Pathol Jpn 1993; 43: 654-61.
15. Driessen A, Nafteux P, Lerut T, et al. Identical cytokeratin expression pattern CK7+/CK20- in esophageal and cardiac cancer: etiopathological and clinical implications. Mod Pathol 2004; 17: 49-55.
16. Muller W, Noguchi T, Wirtz HC, Hommel G, Gabbert HE. Expression of cell-cycle regulatory proteins cyclin D1, cyclin E, and their inhibitor WAF1/CIP1 in gastric cancer. J Pathol 1999; 189: 186-93.