Galactosamine-induced acute liver injury in rats reduces hepatic α-tocopherol transfer protein production

Journal of Nutritional Science and Vitaminology

Volumn 53, Issue 4, 2007, Pages 366-371

  Takenaka, Asako ^a,c   Kita, Akiko ^a   Ikeya, Masafumi ^a   Arai, Hiroyuki ^b   Igarashi, Kiharu ^a  

^a YAMAGATA UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c MEIJI UNIVERSITY   (Japan)

Author keywords

tocopherol transfer protein; TTP; Galactosamine; Liver injury; Rat

Indexed keywords

ALPHA TOCOPHEROL; ALPHA TOCOPHEROL TRANFER PROTEIN; AMINOTRANSFERASE; CARRIER PROTEIN; GALACTOSAMINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; ENZYME ACTIVITY; LIPID BILE LEVEL; LIVER; LIVER INJURY; MALE; NONHUMAN; PROTEIN SYNTHESIS; RAT; TISSUE LEVEL; VITAMIN BLOOD LEVEL;

ALANINE TRANSAMINASE; ALPHA-TOCOPHEROL; ANIMALS; ASPARTATE AMINOTRANSFERASES; BLOTTING, WESTERN; CARRIER PROTEINS; CHOLESTEROL; DISEASE MODELS, ANIMAL; GALACTOSAMINE; L-LACTATE DEHYDROGENASE; LIVER DISEASES; MALE; PHOSPHOLIPIDS; RANDOM ALLOCATION; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRIGLYCERIDES;

RATTUS; RATTUS NORVEGICUS;

EID: 34548826195     PISSN: 03014800     EISSN: 18817742     Source Type: Journal    
DOI: 10.3177/jnsv.53.366     Document Type: Article

References (30)

1. Traber MG, Arai H. 1999. Molecular mechanisms of vitamin E transport. Ann Rev Nutr 19: 343-355.
2. Hamida CB, Doerflinger N, Belal S, Linder C, Reutenauer L, Dib C, Gyapay G, Vignal A, Le Paslier D, Cohen D, Pandolfo M, Mokini V, Movelli G, Hentati F, Ben Hamida M, Mandel J-L, Koenig M. 1993. Localization of Friedreich ataxia phenotype with selective vitamin E deficiency to chromosome 8q by homozygosity mapping. Nature Genetics 5: 195-200.
3. Jishage K, Arita M, Igarashi K, Iwata T, Watanabe M, Ogawa M, Ueda O, Kamada N, Inoue K, Arai H, Suzuki H. 2001. α-Tocopherol transfer protein is important for the normal development of placental labyrinthine trophoblasts in mice. J Biol Chem 276: 1669-1672.
4. Leonard SW, Terasawa Y, Farese Jr RV, Traber MG. 2002. Incorporation of deuterated RRR- or all-rac-α-tocopherol in plasma and tissues of α-tocopherol transfer protein-null mice. Am J Clin Nutr 75: 555-560.
5. Schock BC, Van der Vliet A, Corbacho AM, Leonard SW Finkelstein E, Valacchi G, Obermueller-Jevic U, Cross CE, Traber MG. 2004. Enhanced inflammatory response in α-tocopherol transfer protein null mice. Arch Biochem Biophys 423: 162-169.
6. Shaw H-M, Huang C-J. 1998. Liver α-tocopherol transfer protein and its mRNA are differentially altered by dietary vitamin E deficiency and protein insufficiency in rats. J Nutr 128: 2348-2354.
7. Shaw H-M, Huang C-J. 2000. Secretion of α-tocopherol in VLDL is decreased by dietary protein insufficiency in young growing rats. J Nutr 130: 3050-3054.
8. Yoshikawa T, Takemura S, Kondo M. 1982. Alpha-tocopherol level in liver diseases. Acta Vitaminol Enzymol 4: 311-318.
9. von Herbay A, Stahl W, Niederau C, von Laar J, Strohmeyer G, Sies H. 1996. Diminished plasma levels of vitamin E in patients with severe viral hepatitis. Free Radic Res 25: 461-466.
10. Ferre N, Camps J, Prats E, Girona J, Gomez F, Heras M, Simo JM, Ribalta J, Joven J. 2002. Impaired vitamin E status in patients with parenchymal liver cirrhosis: relationships with lipoprotein compositional alterations, nutritional factors, and oxidative susceptibility of plasma. Metabolism 51: 609-615.
11. Nagita A, Ando M. 1997. Assessment of hepatic vitamin E status in adult patients with liver disease. Hepatology 26: 392-397.
12. Keppler DOR, Pausch J, Decker K. 1974. Selective uridine triphosphate deficiency induced by D-galactosamine in liver and reversed by pyrimidine nucleotide precursors. J Biol Chem 249: 211-216.
13. Muntane J, Montera JL, Marchai T, Perez-Seoane C, Lozano JM, Fraga E, Pintado CO, De la Mata, Mino G. 1998. Effect of PGE1 on TNF-alpha status and hepatic D-galactosamine-induced apoptosis in rats. J Gastroenterol Hepatol. 13: 197-207.
14. Stachlewitz RF, Seabra V, Bradford B, Bradham CA, Rusyn I, Germolec D, Thurman RG. 1999. Glycine and uridine prevent D-galactosamine hepatotoxicity in the rat: role of kupffer cells. Hepatology 29: 737-745.
15. Tsutsui S, Hirasawa K, Takeda M, Itagaki S, Kuwamura S, Maeda K, Mikami T, Doi K. 1997. Galactosamine-induced apoptosis in the primary mouse hepatocyte cultures. Exp Toxicol Pathol 49: 301-306.
16. Sato Y, Arai H, Miyata A, Tokita S, Yamamoto K, Tanabe T, Inoue K. 1993. Primary structure of α-tocopherol transfer protein from rat liver. J Biol Chem 268: 17705-17710.
17. Harada N, Saito S-I, Minakata K. 1991. Effects of vitamin E on toxicity of minute amounts of paraquat fed continuously to rats. J Nutr Sci Vitaminol 37: 1-13.
18. Sugimoto E, Igarashi K, Takenaka A. 2003. Preventive effect of dietary nasunin on galactosamine-induced liver injury in rats. Food Sci Technol Res 9: 94-99.
19. Wroblewski F, LaDue JS. 1955. Lactic dehydrogenase activity in blood. Proc Soc Exp Biol Med 90: 210-213.
20. Folch J, Lees M, Sloane-Stanley GH. 1957. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226: 497-509.
21. Chomczynski P, Sacchi M. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform exrtraction. Anal Biochem 162: 156-159.
22. Puissant C, Houdebine L-M. 1990. An improvement of the single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. BioTechniques 8: 148-149.
23. Miura Y, Kato H, Noguchi T. 1992. Effect of dietary proteins on insulin-like growth factor-1 (IGF-1) messenger ribonucleic acid content in rat liver. Br J Nutr 67: 257-265.
24. Kettermann R, Sirowej H. 1979. Liver injury and lipid metabolism: sex differences in the fatty liver induced by D-galactosamine. Acta Hepatogastroenterol 2: 112-121.
25. Mangeney-Andreani M, Sire O, Motagne-Clavel J, Nordmann R, Nordmann J. 1982. Inhibitory effect of D-galactosamine administration on fatty acid oxidation in rat hepatocytes. FEBS Lett 145: 267-270.
26. Gujral JS, Farhood A, Jaeschke H. 2003. Oncotic necrosis and caspase-dependent apoptosis during galactosamine-induced liver injury in rats. Toxicol Appl Pharmacol 190: 37-46.
27. Kucera O, Cervinkova Z, Lotkova H, Krivakova P, Rousar T, Muzakova V, Hezova R, Kandar R, Rudolf E. 2006. Protective effect of S-adenosylmethionine against galactosamine-induced liver injury of rat hepatocytes in primary culture. Physiol Res 55: 551-560.
28. Barrow L, Patel HR, Tanner MS. 1992. Alpha-tocopherol deficiency fails to aggravate toxic liver injury but liver injury causes alpha-tocopherol retention. J Hepatol 16: 332-337.
29. Rocchi E, Borghi A, Paolillo F, Pradelli M, Casalgrandi G. 1991. Carotenoids and liposoluble vitamins in liver cirrhosis. J Lab Clin Med 118: 176-185.
30. Ravikumar V, Shivashangari KS, Devaki T. 2005. Effect of Tridax procumbens on liver antioxidant defence system during lipopolysaccharide-induced hepatitis in D-galactosamine sensitized rats. Mol Cell Biochem 269: 131-136.