메뉴 건너뛰기




Volumn 11, Issue 9, 2007, Pages 1133-1136

The continuing complexities of high-density lipoprotein metabolism in drug discovery and development

(1)  Suckling, Keith a  

a NONE   (United Kingdom)

Author keywords

Atherosclerosis; CETP inhibitor; HDL; Imaging; Niacin; Torcetrapib

Indexed keywords

2 METHYLPROPANETHIOIC ACID S [2 [1 (2 ETHYLBUTYL)CYCLOHEXYLCARBOXAMIDO]PHENYL] ESTER; FARNESOID X RECEPTOR AGONIST; HIGH DENSITY LIPOPROTEIN; HORMONE RECEPTOR STIMULATING AGENT; LIPID; LIVER X RECEPTOR AGONIST; NICOTINIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; TORCETRAPIB; UNCLASSIFIED DRUG; CETP PROTEIN, HUMAN; CHOLESTEROL ESTER TRANSFER PROTEIN; HYPOCHOLESTEROLEMIC AGENT; QUINOLINE DERIVATIVE;

EID: 34548825124     PISSN: 14728222     EISSN: None     Source Type: Journal    
DOI: 10.1517/14728222.11.9.1133     Document Type: Editorial
Times cited : (6)

References (21)
  • 1
    • 34447520136 scopus 로고    scopus 로고
    • Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women
    • BANSAL S, BURING JE, RIFAI N, MORA S, SACKS FM, RIDKER PM: Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women. JAMA (2007) 298:309-316.
    • (2007) JAMA , vol.298 , pp. 309-316
    • BANSAL, S.1    BURING, J.E.2    RIFAI, N.3    MORA, S.4    SACKS, F.M.5    RIDKER, P.M.6
  • 2
    • 34447511196 scopus 로고    scopus 로고
    • Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women
    • NORDESTGAARD BG, BENN M, SCHNOHR P, TYBJAERG-HANSEN A: Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women. JAMA (2007) 298:299-308.
    • (2007) JAMA , vol.298 , pp. 299-308
    • NORDESTGAARD, B.G.1    BENN, M.2    SCHNOHR, P.3    TYBJAERG-HANSEN, A.4
  • 4
    • 33746766313 scopus 로고    scopus 로고
    • Therapeutic elevation of HDL-cholesterol to prevent atherosclerosis and coronary heart disease
    • CHAPMAN MJ: Therapeutic elevation of HDL-cholesterol to prevent atherosclerosis and coronary heart disease. Pharmacol. Ther. (2006) 111:893-908.
    • (2006) Pharmacol. Ther , vol.111 , pp. 893-908
    • CHAPMAN, M.J.1
  • 7
    • 33750126897 scopus 로고    scopus 로고
    • Discontinued drugs in 2005: Cardiovascular drugs
    • SUCKLING KE: Discontinued drugs in 2005: cardiovascular drugs. Expert Opin. Investig. Drugs (2006) 15:1299-1308.
    • (2006) Expert Opin. Investig. Drugs , vol.15 , pp. 1299-1308
    • SUCKLING, K.E.1
  • 8
    • 34047106220 scopus 로고    scopus 로고
    • Effect of torcetrapib on the progression of coronary atherosclerosis
    • NISSEN SE, TARDIF JC, NICHOLLS SJ et al.: Effect of torcetrapib on the progression of coronary atherosclerosis. N. Engl. J. Med. (2007) 356:1304-1316.
    • (2007) N. Engl. J. Med , vol.356 , pp. 1304-1316
    • NISSEN, S.E.1    TARDIF, J.C.2    NICHOLLS, S.J.3
  • 9
    • 34247241088 scopus 로고    scopus 로고
    • Effect of torcetrapib on carotid atherosclerosis in familial hypercholesterolemia
    • KASTELEIN JJP, VAN LEUVEN SI, BURGESS L et al.: Effect of torcetrapib on carotid atherosclerosis in familial hypercholesterolemia. N. Engl. J. Med. (2007) 356:1620-1630.
    • (2007) N. Engl. J. Med , vol.356 , pp. 1620-1630
    • KASTELEIN, J.J.P.1    VAN LEUVEN, S.I.2    BURGESS, L.3
  • 10
    • 32844470958 scopus 로고    scopus 로고
    • Noninvasive imaging of atherosclerotic vessels by MRI for clinical assessment of the effectiveness of therapy
    • CORTI R: Noninvasive imaging of atherosclerotic vessels by MRI for clinical assessment of the effectiveness of therapy. Pharmacol. Ther. (2006) 110:57-70.
    • (2006) Pharmacol. Ther , vol.110 , pp. 57-70
    • CORTI, R.1
  • 11
    • 33847381474 scopus 로고    scopus 로고
    • Biomarkers in the prevention and treatment of atherosclerosis: Need, validation, and future
    • REVKIN JH, SHEAR CL, POULEUR HG, RYDER SW, ORLOFF DG: Biomarkers in the prevention and treatment of atherosclerosis: need, validation, and future. Pharmacol. Rev. (2007) 59:40-53.
    • (2007) Pharmacol. Rev , vol.59 , pp. 40-53
    • REVKIN, J.H.1    SHEAR, C.L.2    POULEUR, H.G.3    RYDER, S.W.4    ORLOFF, D.G.5
  • 12
    • 33846429592 scopus 로고    scopus 로고
    • Drug insight mechanisms of action and therapeutic applications for agonists of peroxisome proliferator-activated receptors
    • GERVOIS P, FRUCHART J-C, STAELS B: Drug insight mechanisms of action and therapeutic applications for agonists of peroxisome proliferator-activated receptors. Nat. Clin. Practice Endocrinol. Metab. (2007) 3:145-156.
    • (2007) Nat. Clin. Practice Endocrinol. Metab , vol.3 , pp. 145-156
    • GERVOIS, P.1    FRUCHART, J.-C.2    STAELS, B.3
  • 13
    • 33846623798 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors as transcriptional nodal points and therapeutic targets
    • BROWN JD, PLUTZKY J: Peroxisome proliferator-activated receptors as transcriptional nodal points and therapeutic targets. Circulation (2007) 115:518-533.
    • (2007) Circulation , vol.115 , pp. 518-533
    • BROWN, J.D.1    PLUTZKY, J.2
  • 14
    • 34248392648 scopus 로고    scopus 로고
    • Bile acids, farnesoid X receptor, atherosclerosis and metabolic control
    • KUIPERS F, STROEVE JH, CARON S, STAELS B: Bile acids, farnesoid X receptor, atherosclerosis and metabolic control. Curr. Opin. Lipidol. (2007) 18:289-297.
    • (2007) Curr. Opin. Lipidol , vol.18 , pp. 289-297
    • KUIPERS, F.1    STROEVE, J.H.2    CARON, S.3    STAELS, B.4
  • 15
    • 33645068185 scopus 로고    scopus 로고
    • Liver X receptors in cardiovascular and metabolic disease
    • GEYEREGGERR, ZEYDA M, STULNIG TM: Liver X receptors in cardiovascular and metabolic disease. Cell Mol. Life Sci. (2006) 63:524-539.
    • (2006) Cell Mol. Life Sci , vol.63 , pp. 524-539
    • GEYEREGGERR, Z.M.1    STULNIG, T.M.2
  • 16
    • 33644865172 scopus 로고    scopus 로고
    • Pharmacological activation of liver X receptors promotes reverse cholesterol transport in vivo
    • NAIK SU, WANG X, DA SILVA JS et al.: Pharmacological activation of liver X receptors promotes reverse cholesterol transport in vivo. Circulation (2006) 113:90-97.
    • (2006) Circulation , vol.113 , pp. 90-97
    • NAIK, S.U.1    WANG, X.2    DA SILVA, J.S.3
  • 17
    • 34447301242 scopus 로고    scopus 로고
    • New targets of high-density lipoprotein therapy
    • NICHOLLS SJ, NISSEN SE: New targets of high-density lipoprotein therapy. Curr. Opin. Lipidol. (2007) 18:421-426.
    • (2007) Curr. Opin. Lipidol , vol.18 , pp. 421-426
    • NICHOLLS, S.J.1    NISSEN, S.E.2
  • 18
    • 34250179920 scopus 로고    scopus 로고
    • The ideal model in atherosclerosis and dyslipidaemia - does it exist?
    • SUCKLING KE: The ideal model in atherosclerosis and dyslipidaemia - does it exist? Expert Opin. Drug Discov. (2007) 1:507-511.
    • (2007) Expert Opin. Drug Discov , vol.1 , pp. 507-511
    • SUCKLING, K.E.1
  • 19
    • 34447335060 scopus 로고    scopus 로고
    • Niacin in cardiovascular prevention: Mechanisms, efficacy, and safety
    • GUYTON JR: Niacin in cardiovascular prevention: mechanisms, efficacy, and safety. Curr. Opin. Lipidol. (2007) 18:415-420.
    • (2007) Curr. Opin. Lipidol , vol.18 , pp. 415-420
    • GUYTON, J.R.1
  • 20
    • 34247397359 scopus 로고    scopus 로고
    • Effects of reconstituted high-density lipoprotein infusions on coronary atherosclerosis: A randomized controlled trial
    • TARDIF JC, GREGOIRE J, L'ALLIER PL et al.: Effects of reconstituted high-density lipoprotein infusions on coronary atherosclerosis: a randomized controlled trial. JAMA (2007) 297:1675-1682.
    • (2007) JAMA , vol.297 , pp. 1675-1682
    • TARDIF, J.C.1    GREGOIRE, J.2    L'ALLIER, P.L.3
  • 21
    • 33645058160 scopus 로고    scopus 로고
    • A triumvirate of targets in the prevention and treatment paradigm for cardiovascular disease
    • PACKARD C: A triumvirate of targets in the prevention and treatment paradigm for cardiovascular disease. Atheroscler. Suppl. (2006) 7:21-29.
    • (2006) Atheroscler. Suppl , vol.7 , pp. 21-29
    • PACKARD, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.