Protein kinase C δ is a critical regulator of CD1d-mediated antigen presentation

European Journal of Immunology

Volumn 37, Issue 9, 2007, Pages 2390-2395

  Brutkiewicz, Randy R ^a,b   Willard, Claire A ^a,b   Gillett Heacock, Kristin K ^a,b   Pawlak, M Robert ^a,b   Bailey, Jennifer C ^a,b   Khan, Masood A ^a,b   Nagala, Manjula ^a,b   Du, Wenjun ^c   Gervay Hague, Jacquelyn ^c   Renukaradhya, Gourapura J ^a,b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WALTHER CANCER INSTITUTE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Antigen presentation; CD1d; Signal transduction

Indexed keywords

ALPHA GALACTOSYLCERAMIDE; CD1D ANTIGEN; MITOGEN ACTIVATED PROTEIN KINASE; MUTANT PROTEIN; PROTEIN KINASE C DELTA; REGULATOR PROTEIN;

ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; CELL SURFACE; CELLULAR DISTRIBUTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; MOUSE; NATURAL KILLER T CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

EID: 34548797189     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200737124     Document Type: Article

References (17)

1. Brutkiewicz, R. R., Lin, Y., Cho, S., Hwang, Y. K, Sriram, V. and Roberts, T. J., CD1d-mediated antigen presentation to natural killer T (NKT) cells. Crit. Rev. Immunol. 2003. 23: 403-419.
2. Renukaradhya, G. J., Roberts Webb, T. J., Khan, M. A., Lin, Y. L., Du, W., Gervay-Hague, J. and Brutkiewicz, R. R., Virus-induced inhibition of CDldl-mediated antigen presentation: Reciprocal regulation by p38 and ERK. J. Immunol. 2005. 175: 4301-4308.
3. Steinberg, S. F., Distinctive activation mechanisms and functions for protein kinase Cδ. Biochem. J. 2004. 384: 149-459.
4. 2 in FcεRI signaling to cysteinyl leukotriene synthesis in mast cells. J. Immunol. 2004. 173: 624-631.
5. Kikkawa, U., Matsuzaki, H. and Yamamoto, T., Protein kinase C δ (PKC δ): Activation mechanisms and functions. J. Biochem. 2002. 132: 831-839.
6. Hirai, S., Izurai, Y., Higa, K, Kaibuchi, K, Mizuno, K., Osada, S., Suzuki, K. and Ohno, S., Ras-dependent signal transduction is indispensable but not sufficient for the activation of AP1/Jun by PKCδ. EMBO J. 1994. 13: 2331-2340.
7. 2 expression via sequential PKC-δ, p42/p44 MAPK, and NF-κB activation in rat brain astrocytes. J. Cell. Physiol. 2006. 206: 246-254.
8. Keshamouni, V. G., Mattingly, R. R. and Reddy, K. B., Mechanism of 17-β-estradiol-induced Erk1/2 activation in breast cancer cells. A role for HER2 and PKC-δ. J. Biol. Chem. 2002. 277: 22558-22565.
9. Yamaguchi, H., Igarashi, M., Hirata, A., Sugae, N., Tsuchiya, H., Jimbu, Y., Tominaga, M. and Kato, T., Altered PDGF-BB-induced p38 MAP kinase activation in diabetic vascular smooth muscle cells: Roles of protein kinase C-δ. Arterioscler. Thromb. Vasc. Biol. 2004. 24: 2095-2101.
10. + T cell lymphoma by natural killer T (NKT) cells. Proc. Natl. Acad. Sci. USA 2002. 99: 8197-8202.
11. + T lymphocytes. Science 1995. 268: 863-865.
12. - T cells in mice and humans. J. Exp. Med. 1994. 180: 1097-1106.
13. Gui, M., Li, J., Wen, L. J., Hardy, R. R. and Hayakawa, K., TCR β chain influences but does not solely control autoreactivity of Vαl4Jα281 T cells. J Immunol. 2001. 167: 6239-6246.
14. Roberts, T. J., Sriram, V., Spence, P. M., Gui, M., Hayakawa, K., Bacik, I., Bermink, J. R. et al., Recycling CD1d1 molecules present endogenous antigens processed in an endocytic compartment to NKT cells. J. Immunol. 2002. 168: 5409-5414.
15. Du, W. and Gervay-Hague, J., Efficient synthesis of α-galactosyl ceramide analogues using glycosyl iodide donors. Org. Lett. 2005. 7: 2063-2065.
16. Sriram, V., Du, W., Gervay-Hague, J. and Brutkiewicz, R. R., Cell wall glycosphingolipids of Sphingomonas paucimobilis are CDld-specific ligands for NKT cells. Eur. J. Immunol. 2005. 35: 1692-1701.
17. Yuan, W., Dasgupta, A. and Cresswell, P., Herpes simplex virus evades natural killer T cell recognition by suppressing CDld recycling. Nat. Immunol. 2006. 7: 835-842.