Antihyperglycaemic activity of petroleum ether extract of Ficus racemosa fruits in alloxan induced diabetic mice

Pharmacologyonline

Volumn 2, Issue , 2007, Pages 504-515

  Deshmukh, Tushar A ^a   Yadav, Bapuso V ^a   Badole, Sachin L ^a   Bodhankar, Subhash L ^a   Dhaneshwar, Sunil R ^a  

^a BHARATI VIDYAPEETH DEEMED UNIVERSITY   (India)

Author keywords

Alloxan; Antihyperglycaemic; Body weight; Ficus racemosa; Oral glucose tolerance test

Indexed keywords

ALLOXAN; FICUS RACEMOSA EXTRACT; GLIBENCLAMIDE; GLUCOSE; PETROLEUM ETHER; PLANT EXTRACT; UNCLASSIFIED DRUG;

ALLOXAN DIABETES MELLITUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; FICUS; FICUS RACEMOSA; FRUIT; GLUCOSE BLOOD LEVEL; MOUSE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; OUTCOME ASSESSMENT; REPEATED DRUG DOSE; TREATMENT DURATION; WEIGHT REDUCTION;

EID: 34548796041     PISSN: None     EISSN: 18278620     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Vetrichelvan T, Jegadeesan M. Anti-diabetic activity of alcoholic extract of Aerva lanata (L.) Juss. ex Schultes in rats. J. Ethnopharmacology. 2002; 80:103-107.
2. Edwin E, Sheeja E, Chaturvedi M, Sharma s, Gupta VB. A comparative study on antihyperglycemic activity of fruits and barks of Ficus bengalensis, Linn. Adv. Pharmacol. Toxicol. 2006; 7(3): 69-71.
3. Shah SN, Bodhankar SL, Bhonde R, Mohan V. Hypoglycemic activity of the combination of active ingredients isolated from Trigonella foenumgraecum in alloxan induced diabetic mice. Pharmacologyonline. 2006; 1: 65-82.
4. Kirtikar KR, Basu BD. Indian Medicinal Plants. Vol. 10. 2nd ed: Uttaranchal: Oriental Enterprises; 2001: 3216-3219.
5. Ramankutty C, Nambair VPK. Indian Medicinal Plants- A Compendium of 500 Species. Vol III. Kottakkal: Orient Longman Limited; 1996: 34-37.
6. Patil KS, Warke PD, Chaturvedi SC. Hypoglycemic properties of Ficus glomerata fruits in alloxan-induced diabetic rats. Journal of Natural Remedies. 2006; 6(2): 120-123.
7. Organization for Economic Co-operation and Development. OECD Guidelines for the Testing of Chemicals. OECD Guideline 425: Acute Oral Toxicity: Up-and-Down Procedure, June 1998.
8. Kameswararao BK, Kesavulu MM, Giri R, Appa Rao C. Antidiabetic and hypolipidemic effects of Momordica cymbalaria Hook. fiuit powder in alloxan-diabetic rats. J. Ethnopharmacology. 1999; 67(1):103-109.
9. Abdel-Barry JA, Abdel-Hassan IA, Al-Hakiem MH. Hypoglycemic and antihyperglycaemic effects of Trigonella foenum-graecum leaf in normal and alloxan induced diabetic rats. J. Ethnopharmacology. 1997; 58(3):149-155.
10. Badole SL, Shah SN, Thakurdesai PA, Bodhankar SL, et al. Hypoglycemic activity of aqueous extract of Pleurotus pulmonarius (Fr.) Quel- Champ in alloxan induced diabetic mice. Pharmaceutical Biology. 2006; 44(6): 421-425.
11. One-way ANOVA with Tukey's post test was performed using GraphPad InStat version 3.01 for Windows 95, GraphPad Software Inc., 5755 Oberlin drive, #110, San Diego California 92121, USA www.graphad.com.
12. Krishnamurthi A. The Wealth of India, A dictionary of Indian Raw Materials. Vol. III. D-I. New Delhi: CSIR; 2003: 130.
13. Rahman NN, Khan M, Hasan R. Bioactive components from Ficus glomerata. Pure and Appl. Chem. 1994; 66(10/11):2287-2290.
14. Xie TT, Wang A, Mehendale S, Wu J, Aung HH, Dey L, Qiu S, Yuan CS. Antidiabetic effect of Gymnema yannaense extract. Pharmacol. Res. 2003; 47: 323-329.
15. Latha M, Pari L. Antihyperglycaemic effect of Cassia auriculata in experimental diabetes and its effect on key metabolic enzymes involved in carbohydrate metabolism. Clin. Exp. Pharmacol. Physiol. 2003; 30: 38-43.
16. Evans WC. Trease and Evans Pharmacognosy.15th ed. London: Saunders Company; 2002: 419.
17. Harborne JB. Phytochemical Methods. 2nd ed. New Delhi: Chapman and Hall Academic Press; 1984: 126.
18. Catopano AL. Antioxident effect of flavonoids. Angiol.1997; 48: 39-46.
19. Kameswararao B, Giri R, Kesavulu MM, Apparao, C. Herbal medicines: In the treatment of diabetes mellitus. Manphar Vaidya Patrika. 1997; 1: 33-35.
20. Chandra S, Jawahar Lal, Sabir M. Chemical examination of the fruits of Ficus glomerata Roxb.Journal of Indian Chem. Soci. 1979; 56: 1269.
21. Merchant JR, Engineer AB. Chemical investigation of the fruits of Ficus glomerata Roxb. 1979; 17B January: 87-88.