Increased nitric oxide production during acute rejection in kidney transplantation: A useful marker to aid in the diagnosis of rejection

Transplantation

Volumn 84, Issue 5, 2007, Pages 580-586

  Khanafer, Adib ^a,b   Ilham, Mohamad A ^a   Namagondlu, Girish S ^a   Janzic, Alanka ^a   Sikas, Niros ^a   Smith, Dona ^a   Griffiths, David ^a   Chavez, Rapheal ^a   Asderakis, Argiris ^a  

^a UNIVERSITY HOSPITAL OF WALES   (United Kingdom)

^b NONE   (United Kingdom)

Author keywords

Acute rejection; Nitric oxide; Serum nitrate; Tacrolimus toxicity; Urinary tract infection

Indexed keywords

AZATHIOPRINE; CREATININE; INTERLEUKIN 2 RECEPTOR ANTIBODY; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; NITRATE; NITRIC OXIDE; OKT 3; RAPAMYCIN; TACROLIMUS;

ADULT; AGED; ARTICLE; BIOPSY; BLOOD SAMPLING; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DISEASE MARKER; DRUG BLOOD LEVEL; FEMALE; HUMAN; HUMAN TISSUE; KIDNEY FAILURE; KIDNEY FUNCTION TEST; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; MALE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RECIPIENT; SINGLE DRUG DOSE; STATISTICAL SIGNIFICANCE; URINALYSIS; URINARY TRACT INFECTION;

ACUTE DISEASE; ADULT; BIOLOGICAL MARKERS; BIOPSY; CREATINE; FEMALE; GRAFT REJECTION; GRAFT SURVIVAL; HEALTH; HUMANS; KIDNEY FAILURE; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; NITRATES; NITRIC OXIDE; PITUITARY HORMONES; TACROLIMUS;

EID: 34548783338     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.tp.0000278120.55796.42     Document Type: Article

References (40)

1. Krieger NR, Becker BN, Heisey DM, et al. Chronic allograft nephropathy uniformly affects recipients of cadaveric, non identical living related and living unrelated grafts. Transplantation 2003; 75: 1677.
2. Meier-Kriesche HU, Ojo AO, Hanson JA, et al. Increased impact of acute rejection on chronic allograft failure in recent era. Transplantation 2000; 70: 1098.
3. Gulanikar AC, MacDonald AS, Sungurtekin U, Belitsky p. The incidence and impact of early rejection episodes on graft outcome in recipients of first cadaver kidney transplant. Transplantation 1992; 53: 323.
4. Flechner SM, Modlin CS, Serrano DP, et al. Determinants of chronic renal failure allograft rejection in cyclosporine-treated recipients. Transplantation 1996; 62: 1235.
5. Massy ZA, Guijarro C, Weiderkehr MR, Ma JZ, Kasiske BL. Chronic renal allograft rejection: Immunological and nonimmunological risk factors. Kidney Int 1996; 49: 518.
6. Baogui Li, Hartono C, Ding R, et al. Noninvasive diagnosis of renal-allograft rejection by measurement of messenger RNA for perforin and granzyme B in urine. N Engl J Med 2001; 344: 947.
7. Hancock WW, Gee D, Moerloose PD, Rickles FR, Ewan VA, Atkins RC. Immunohistological analysis of serial biopsies taken during human renal allograft rejection. Transplantation 1995; 39: 430.
8. Joles JA, Vos HI, Grone HJ, Rabelink TJ. Inducible nitric oxide synthase in renal transplantation (review). Kidney Int. 2002; 61: 872.
9. Morris SM, Billiar TR. New insights into the regulation of inducible nitric oxide synthesis. Am J. Physiol. 1994; 266: E829.
10. Morrissey JJ, McCracken, Kaneto H, Vehaskari M, Montani D, Klahr S. Location of an inducible nitric oxide synthase mRNA in the normal kidney. Kidney Int 1994; 45: 998.
11. Cattell V, Smith J, Jansen A, Riveros-Moreno V, Moncada S. Localization of indcible nitric oxide synthase in acute renal allograft rejection in the rat. Transplantation 1994; 58: 1399.
12. Davies MG, Fulton GJ, Hagen PO. Clinical biology of nitric oxide. Br J Surg 1995; 82: 1598.
13. Devlin J, Palmer RMJ, Gonde CE, et al. Nitric oxide generation: A predictive parameter of acute allograft rejection. Transplantation 1994; 58: 592.
14. Joles JA, Vos IH, Grone HJ, Rabelink TJ. Inducible nitric oxide synthase in renal transplantation. Kidney Int 2002; 61: 872.
15. Langrehr JM, White DA, Hoffman RA, Simmons RL. Macrophages produce nitic oxide at allograft site. Ann Surg 1993; 218: 159.
16. Radomski MW, Palmer RMJ, Moncada S. Glucocorticoids inhibit the expression of an inducible but not the constitutive nitric oxide synthase in vascular endothelium. Proc Natl Acad Sci U S A 1990; 87: 10043.
17. Takahashi N, Suzuki T, Yamaya K, Funyu T. Nitric Oxide generation in renal allograft recipients. Transplant Proc 1998; 30: 2960.
18. Paul LC, Myllarniemi M, Muzaffar S, Benediktsson H. Nitric oxide synthase Inhibition is associated with decreased survival of cardiac allografts in the rats. Transplantation 1996; 62: 1193.
19. Hirabayashi N, Tanimura H, Yamaue H. Nitrite/nitrate oxide and cytokines changes inpatients with surgical stress [abstract]. Dig Dis Sci 2005; 50: 893.
20. Moshage H, Kok B, Huizenga JR, Jansen PLM. Nitrite and Nitrate determinations in plasma: A critical evaluation. Clin Chem 1995; 41: 892.
21. Schmidt HHW, Kelm M. Determination of nitrite and nitrate by the Griess reaction. In: Feelisch M, Stamler JS, eds. Methods in Nnitric Oxide Research. Chichester: John Wiley & Sons; 1996: 491.
22. Bories PN, Bories C. Nitrate determination in biological fluids by an enzymatic one-step assay with nitrate reductase. Clin Chem 1995; 41: 904.
23. Salgado O. Noninvasive acute rejection diagnosis in kidney transplantation. Transplant Proc 2002; 34: 2543.
24. Albriecht EWJ, Van Goor H, Tiebosch ATMG, Moshage H, Tegzess AM, Stegeman CA. Nitric oxide production and nitric oxide synthase expression in acute human renal allograft rejection. Transplantation 2000; 70: 1610.
25. Langrehr JM, Nuras N, Markus PM, et al. Nitric oxide production in host-versus-graft and graft-versus-host reactions in the rat. J Clin Invest 1992; 90: 679.
26. Langrehr JM, Hoffman RA, Billiar TR, Lee KKW, Schraut W, Simmons R. Nitric oxide synthesis in the vivo allograft response: a possible regulatory mechanism. Surgery 1991; 110: 335.
27. Dedeoglu O, Feld LG. Decreased urinary excretion of nitric oxide in acute rejection episodes in pediatric renal allograft recipients. Transplantation 1996; 62: 1936.
28. Green LC, Wagner DA, Glogowski J, Skipper PL, Wishnok JS, Tannenbaum SR. Analysis of nitrate, nitrite and [15N] nitrate in biological fluids. Anal Biochem 1982; 126: 131.
29. Shiraishi T, DeMeester SR, Worrall NK, et al. Inhibition of inducible nitric oxide synthase ameliorates rat lung allograft rejection. J Thorac Cardiovasc Surg 1995; 110: 1449.
30. Smith SD, Wheeler MA, Zhang R, et al. Nitric oxide synthase induction with renal transplant rejection or infection. Kidney Int 1996; 50: 2088.
31. Wong HR, Carcillo JA, Burckart G, Shah N, Janosky JE. Increased serum nitrite and nitrate concentrations in children with the sepsis syndrome (abstr). Crit Care Med 1995; 23: 835.
32. Ahren C, Jungersten L, Sandberg T. Plasma nitrate as an index of nitric oxide formation in patients with acute infectious diseases. Scand J Infect Dis 1999; 31: 405.
33. Stark ME, Szurszewski JH. Role of nitric oxide in gastrointestinal and hepatic function and disease. Gastroenterology 1992; 103: 1928.
34. Erickson LM, Pan F, Ebbs A, Kobayashi M, Jiang H. Microarray-based gene expression profiles of allograft rejection and immunosuppression in the rat heart transplantation model. Transplantation 2003; 76: 582.
35. Shin GT, Kim SJ, Lee TS, Oh CK, Kim H. Gene expression of perforin by peripheral blood lymphocytes as a marker of acute rejection. Nephron Clin Pract 2005; 100: c63.
36. Simon T, Opelz G, Wiesel M, Ott RC, Susal C. Serial peripheral blood perforin and granzym B gene expression measurements for prediction of acute rejection in kidney graft recipients. Am J Transplant 2003; 3: 1121.
37. Aquino Dias EC, Veronese FJ, Santos Goncalves LF, Manfro RC. Molecular markers in subclinical acute rejection of renal transplants. Clin Transplant 2004; 18: 281.
38. Storm TB, Suthanthiran M. Prospects and applicability of molecular diagnosis of allograft rejection. Semin Nephrol 2000; 20: 103.
39. Schmidt RJ, Baylis C. Total nitric oxide production is low in patients with chronic renal disease. Kidney Int 2000; 58: 1261.
40. Goligorsky MS, Brodsky SV, Noiri E. Nitric oxide in acute renal failure: NOS versus NOS. Kidney Int 2002; 61: 855.