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Volumn 9, Issue SUPPL.1, 2007, Pages 32-39

The DPP-4 inhibitor vildagliptin: Robust glycaemic control in type 2 diabetes and beyond

Author keywords

Combination therapy; Dipeptidyl peptidase 4; Prediabetes; Type 2 diabetes mellitus; Vildagliptin; cell function

Indexed keywords

DIPEPTIDYL PEPTIDASE IV; DIPEPTIDYL PEPTIDASE IV INHIBITOR; GLIMEPIRIDE; GLUCAGON; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; HEMOGLOBIN A1C; INSULIN; LIPID; METFORMIN; PIOGLITAZONE; PLACEBO; ROSIGLITAZONE; VILDAGLIPTIN;

EID: 34548763078     PISSN: 14628902     EISSN: 14631326     Source Type: Journal    
DOI: 10.1111/j.1463-1326.2007.00763.x     Document Type: Review
Times cited : (19)

References (19)
  • 1
    • 2442482515 scopus 로고    scopus 로고
    • Inhibition of dipeptidyl peptidase-4 reduces glycemia, sustains insulin levels and reduces glucagon levels in type 2 diabetes
    • Ahren B, Landin-Olsson M, Jansson P et al. Inhibition of dipeptidyl peptidase-4 reduces glycemia, sustains insulin levels and reduces glucagon levels in type 2 diabetes. J Clin Endocrinol Metab 2004; 89: 2078-2084.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 2078-2084
    • Ahren, B.1    Landin-Olsson, M.2    Jansson, P.3
  • 2
    • 23844463766 scopus 로고    scopus 로고
    • Vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed beta-cell function in patients with type 2 diabetes
    • Mari A, Sallas WM, He YL et al. Vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed beta-cell function in patients with type 2 diabetes. J Clin Endocrinol Metab 2005; 90: 4888-4894.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 4888-4894
    • Mari, A.1    Sallas, W.M.2    He, Y.L.3
  • 3
    • 0037777695 scopus 로고    scopus 로고
    • 1- (3-hydroxy-1-damantly)amino]acetyl]-2-cyano-(S)-pyrrolidine: A potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties
    • Villhauer EB, Brinkman JA, Naderi GB et al. 1- (3-hydroxy-1-damantly)ami no]acetyl]-2-cyano-(S)-pyrrolidine: A potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties. J Med Chem 2003; 46: 2774-2789.
    • (2003) J Med Chem , vol.46 , pp. 2774-2789
    • Villhauer, E.B.1    Brinkman, J.A.2    Naderi, G.B.3
  • 4
    • 34147189738 scopus 로고    scopus 로고
    • The dipeptidyl peptidase IV inhibitor vildagliptin suppresses endogenous glucose production and enhances islet function after single-dose administration in type 2 diabetic patients
    • Balas B, Baig MR, Watson C et al. The dipeptidyl peptidase IV inhibitor vildagliptin suppresses endogenous glucose production and enhances islet function after single-dose administration in type 2 diabetic patients. J Clin Endocrinol Metab 2007; 92: 1249-1255.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 1249-1255
    • Balas, B.1    Baig, M.R.2    Watson, C.3
  • 5
    • 34548118796 scopus 로고    scopus 로고
    • Comparison between vildagliptin and metformin to sustain reductions in HbA(1c) over 1 year in drug-naive patients with type 2 diabetes
    • (Epub ahead of print)
    • Schweizer A, Couturier A, Foley JE, Dejager S. Comparison between vildagliptin and metformin to sustain reductions in HbA(1c) over 1 year in drug-naive patients with type 2 diabetes. Diabet Med 2007 (Epub ahead of print).
    • (2007) Diabet Med
    • Schweizer, A.1    Couturier, A.2    Foley, J.E.3    Dejager, S.4
  • 6
    • 33846694046 scopus 로고    scopus 로고
    • Comparison of vildagliptin and rosiglitazone monotherapy in patients with type 2 diabetes
    • Rosenstock J, Baron MA, Dejager S et al. Comparison of vildagliptin and rosiglitazone monotherapy in patients with type 2 diabetes. Diabetes Care 2007; 30: 217-223.
    • (2007) Diabetes Care , vol.30 , pp. 217-223
    • Rosenstock, J.1    Baron, M.A.2    Dejager, S.3
  • 7
    • 9444285818 scopus 로고    scopus 로고
    • Twelve- and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF 237 in metformin-treated patients with type 2 diabetes
    • Ahrén B, Gomis R, Standl E et al. Twelve- and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF 237 in metformin-treated patients with type 2 diabetes. Diabetes Care 2004; 27: 2874-2880.
    • (2004) Diabetes Care , vol.27 , pp. 2874-2880
    • Ahrén, B.1    Gomis, R.2    Standl, E.3
  • 8
    • 34147093268 scopus 로고    scopus 로고
    • Effects of vildagliptin on glucose control over 24 weeks in patients with type 2 diabetes inadequately controlled with metformin
    • Bosi E, Camisasca RP, Collober C et al. Effects of vildagliptin on glucose control over 24 weeks in patients with type 2 diabetes inadequately controlled with metformin. Diabetes Care 2007; 30: 890-895.
    • (2007) Diabetes Care , vol.30 , pp. 890-895
    • Bosi, E.1    Camisasca, R.P.2    Collober, C.3
  • 9
    • 34548705729 scopus 로고    scopus 로고
    • Efficacy and tolerability of vildagliptin added to a sulfonylurea (SU) in patients with type 2 diabetes (T2DM)
    • Abstract 501-P
    • Garber AJ, Camisasca RP, Jauffret S, Baron MA. Efficacy and tolerability of vildagliptin added to a sulfonylurea (SU) in patients with type 2 diabetes (T2DM). Diabetes 2007; 56 (Suppl. 1): A134. Abstract 501-P.
    • (2007) Diabetes , vol.56 , Issue.SUPPL. 1
    • Garber, A.J.1    Camisasca, R.P.2    Jauffret, S.3    Baron, M.A.4
  • 10
    • 34247874561 scopus 로고    scopus 로고
    • Addition of vildagliptin to insulin improves glycaemic control in type 2 diabetes
    • Fonseca V, Schweizer A, Albrecht D et al. Addition of vildagliptin to insulin improves glycaemic control in type 2 diabetes. Diabetologia 2007; 50: 1148-1155.
    • (2007) Diabetologia , vol.50 , pp. 1148-1155
    • Fonseca, V.1    Schweizer, A.2    Albrecht, D.3
  • 11
    • 34548770945 scopus 로고    scopus 로고
    • Effects of vildagliptin in subjects with IGT
    • Abstract 505-P
    • Rosenstock J, Rendell MS, Landin-Olsson M et al. Effects of vildagliptin in subjects with IGT. Diabetes 2007; 56 (Suppl. 1): A135. Abstract 505-P.
    • (2007) Diabetes , vol.56 , Issue.SUPPL. 1
    • Rosenstock, J.1    Rendell, M.S.2    Landin-Olsson, M.3
  • 12
    • 34147208931 scopus 로고    scopus 로고
    • Pharmacodynamics of vildagliptin in patients with type 2 diabetes during OGTT
    • He Y-L, Wang Y, Bullock JM et al. Pharmacodynamics of vildagliptin in patients with type 2 diabetes during OGTT. J Clin Pharmacol 2007; 47: 633-641.
    • (2007) J Clin Pharmacol , vol.47 , pp. 633-641
    • He, Y.-L.1    Wang, Y.2    Bullock, J.M.3
  • 13
    • 33846905487 scopus 로고    scopus 로고
    • Efficacy and tolerability of vildagliptin monotherapy in drug-naïve patients with type 2 diabetes
    • doi: 10.1016/j.diabres.2006.12.009
    • Pi-Sunyer FX, Schweizer A, Mills D, Dejager S. Efficacy and tolerability of vildagliptin monotherapy in drug-naïve patients with type 2 diabetes. Diabetes Res Clin Pract 2007; 76: 132-138. doi: 10.1016/ j.diabres.2006.12.009
    • (2007) Diabetes Res Clin Pract , vol.76 , pp. 132-138
    • Pi-Sunyer, F.X.1    Schweizer, A.2    Mills, D.3    Dejager, S.4
  • 15
    • 34548705729 scopus 로고    scopus 로고
    • Efficacy and tolerability of vildagliptin in drug-naïve patients with type 2 diabetes (T2DM) and mild hyperglycemia
    • Abstract 503-P
    • Scherbaum WA, Schweizer A, Mari A et al. Efficacy and tolerability of vildagliptin in drug-naïve patients with type 2 diabetes (T2DM) and mild hyperglycemia. Diabetes 2007; 56 (Suppl. 1): A134. Abstract 503-P.
    • (2007) Diabetes , vol.56 , Issue.SUPPL. 1
    • Scherbaum, W.A.1    Schweizer, A.2    Mari, A.3
  • 16
    • 33751089505 scopus 로고    scopus 로고
    • The use of vildagliptin for treatment of patients with type 2 diabetes mellitus
    • Presented at Washington, DC, 13 June
    • Nathwani A. The use of vildagliptin for treatment of patients with type 2 diabetes mellitus. Presented at American Diabetes Association - 66th Scientific Sessions, Washington, DC, 13 June 2006.
    • (2006) American Diabetes Association - 66th Scientific Sessions
    • Nathwani, A.1
  • 17
    • 23044487247 scopus 로고    scopus 로고
    • Improved meal-related β-cell function and insulin sensitivity by the dipeptidyl peptidase IV inhibitor vildagliptin in metformin-treated patients with type 2 diabetes over 1 year
    • Ahrén B, Pacini G, Foley J et al. Improved meal-related β-cell function and insulin sensitivity by the dipeptidyl peptidase IV inhibitor vildagliptin in metformin-treated patients with type 2 diabetes over 1 year. Diabetes Care 2005; 28: 1936-1940.
    • (2005) Diabetes Care , vol.28 , pp. 1936-1940
    • Ahrén, B.1    Pacini, G.2    Foley, J.3
  • 18
    • 33846828660 scopus 로고    scopus 로고
    • Vildagliptin in combination with pioglitazone improves glycaemic control in patients with type 2 diabetes failing thiazolidinedione monotherapy: A randomized, placebo-controlled study
    • Garber AJ, Schweizer A, Baron MA et al. Vildagliptin in combination with pioglitazone improves glycaemic control in patients with type 2 diabetes failing thiazolidinedione monotherapy: A randomized, placebo-controlled study. Diabetes Obes Metab 2007; 9: 166-174.
    • (2007) Diabetes Obes Metab , vol.9 , pp. 166-174
    • Garber, A.J.1    Schweizer, A.2    Baron, M.A.3
  • 19
    • 33846827085 scopus 로고    scopus 로고
    • Efficacy and tolerability of initial combination therapy with vildagliptin and pioglitazone compared with component monotherapy in patients with type 2 diabetes
    • Rosenstock J, Baron MA, Camisasca R-P et al. Efficacy and tolerability of initial combination therapy with vildagliptin and pioglitazone compared with component monotherapy in patients with type 2 diabetes. Diabetes Obes Metab 2007; 9: 175-185.
    • (2007) Diabetes Obes Metab , vol.9 , pp. 175-185
    • Rosenstock, J.1    Baron, M.A.2    Camisasca, R.-P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.