Interaction of β2-glycoprotein 1 with phosphatidylserine-containing membranes: Ligand-dependent conformational alterations initiate bivalent binding

Biochemistry

Volumn 46, Issue 37, 2007, Pages 10612-10620

  Hamdan, Randala ^a   Maiti, Sourindra N ^a   Schroit, Alan J ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONS; IONIC STRENGTH; LIGANDS; MEMBRANES; PHOSPHOLIPIDS; SPECTRUM ANALYSIS;

BIVALENT BINDING; LIPID BINDING; SHORT CONSENSUS REPEAT (SCR); TRYPTOPHAN;

PROTEINS;

ACRYLAMIDE; BETA2 GLYCOPROTEIN 1; CELL SURFACE RECEPTOR; LIGAND; PHOSPHATIDYLSERINE; RECOMBINANT PROTEIN; TRYPTOPHAN; LIPOSOME; PHOSPHATIDYLCHOLINE;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; ENERGY TRANSFER; IONIC STRENGTH; LIPID MEMBRANE; MEMBRANE VESICLE; PRECIPITATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN LIPID INTERACTION; ANIMAL; CATTLE; CHEMISTRY; GENE DELETION; HUMAN; KINETICS; METABOLISM; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; STRUCTURE ACTIVITY RELATION;

ANIMALS; BETA 2-GLYCOPROTEIN I; CATTLE; CHEMICAL PRECIPITATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENERGY TRANSFER; HUMANS; KINETICS; LIGANDS; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLSERINES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SEQUENCE DELETION; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPTOPHAN; UNILAMELLAR LIPOSOMES;

EID: 34548751157     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi700621j     Document Type: Article

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