Diffusion of ertapenem into bone and synovial tissues

Journal of Antimicrobial Chemotherapy

Volumn 60, Issue 4, 2007, Pages 893-896

  Breilh, D ^b   Boselli, Emmanuel ^a   Bel, J C ^a   Saux, M C ^b   Allaouchiche, B ^a   Djabarouti, S ^b  

^a Édouard Herriot ^*  (France)

^b HAUT LÉVÊQUE HOSPITAL   (France)

Author keywords

Bone infection; Diffusion; Pharmacokinetics

Indexed keywords

CEFAZOLIN; ERTAPENEM;

AEROBIC BACTERIUM; AGED; ANAEROBIC BACTERIUM; ARTICLE; BLOOD SAMPLING; BONE; CANCELLOUS BONE; CONTROLLED STUDY; CORTICAL BONE; DRUG BLOOD LEVEL; DRUG DIFFUSION; DRUG PENETRATION; DRUG TISSUE LEVEL; ELECTIVE SURGERY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; MALE; MINIMUM INHIBITORY CONCENTRATION; OPEN STUDY; POSTOPERATIVE INFECTION; QUANTITATIVE ANALYSIS; SINGLE DRUG DOSE; SYNOVIUM; TOTAL HIP PROSTHESIS; VOLUNTEER;

ADULT; AGED; ANTI-BACTERIAL AGENTS; BACTERIA, AEROBIC; BACTERIA, ANAEROBIC; BETA-LACTAMS; BONE AND BONES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; HUMANS; MALE; MICROBIAL SENSITIVITY TESTS; SERUM; SYNOVIAL FLUID; TIME FACTORS;

EID: 34548745725     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkm296     Document Type: Article

References (10)

1. Lew DP, Waldvogel FA. Osteomyelitis. Lancet 2004; 364: 369-79.
2. Boselli E, Allaouchiche B. Diffusion osseuse des antibiotiques. Presse Med 1999; 28: 2265-76.
3. Keating GM, Perry CM. Ertapenem: A review of its use in the treatment of bacterial infections. Drugs 2005; 65: 2151-78.
4. Hammond ML. Ertapenem: A Group 1 carbapenem with distinct antibacterial and pharmacological properties. J Antimicrob Chemother 2004; 53 Suppl 2: 117-9.
5. Livermore DM, Sefton AM, Scott GM. Properties and potential of ertapenem. J Antimicrob Chemother 23; 52: 331-44.
6. Shah PM, Isaacs RD. Ertapenem, the first of a now group of carbapenems. J Antimicrob Chemother 2003; 52: 538-42.
7. Wexler HM. In vitro activity of ertapenem: Review of recent studies. J Antimicrob Chemother 2004; 53 Suppl 2: Ii11-21.
8. Gordien JB, Boselli E, Fleureau C et al. Determination of tree ertapenem in plasma and bronchoalveolar lavage by high-performance liquid chromatography with ultraviolat detection. J Chromatogr B Analyt Technol Biomed Life Sci 2006; 830: 218-23.
9. Zhanel GG, Johanson C, Embil JM et al. Ertapenem: Review of a new carbapenem. Expert Rev Anti Infect Ther 2005; 3: 23-39.
10. Lipsky BA, Armstrong DG, Citron DM et al. Ertapenem versus piperacillin/tazobactam for diabetic foot infections (SIDESTEP): prospective, randomised, controlled, double-blinded, multicentre trial. Lancet 2005; 366: 1695-703.