HIV-1 fusion peptide decreases bending energy and promotes curved fusion intermediates

Biophysical Journal

Volumn 93, Issue 6, 2007, Pages 2048-2055

  Tristram Nagle, Stephanie ^a   Nagle, John F ^a  

^a CARNEGIE MELLON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIOLEOYLPHOSPHATIDYLCHOLINE; HYBRID PROTEIN;

ARTICLE; DATA ANALYSIS; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDRATION; LIPID BILAYER; MEMBRANE FUSION; NONHUMAN; RADIATION SCATTERING; T LYMPHOCYTE; THIN LAYER CHROMATOGRAPHY; VIRUS ENVELOPE;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 34548726186     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1529/biophysj.107.109181     Document Type: Article

References (45)

1. Blumenthal, R., M. J. Clague, S. R. Durell, and R. M. Epand. 2003. Membrane fusion. Chem. Rev. 103:53-69.
2. III/LAV envelope gene. Science. 229:1402-1405.
3. Lasky, A. L., G. Nakamura, D. H. Smith, C. Fennie, C. Shimasaki, E. Patzer, P. Berman, T. Gregory, and D. J. Capon. 1987. Delineation of a region of the hyman-immunodeficiency-virus type-1 gp120 glycoprotein critical for interaction with the CD4 receptor. Cell. 50:975-985.
4. Choe, H., M. Farzan, Y. Sun, N. Sullivan, B. Rollins, P. D. Porath, L. J. Wu, C. R. Mackay, G. LaRosa, W. Newman, N. Gerard, C. Gerard, and J. Sodroski. 1996. The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell. 85:1135-1148.
5. Gallaher, W. R. 1987. Detection of a fusion peptide sequence in the transmembrane protein of human-immunodeficiency-virus. Cell. 50:327-328.
6. Bosch, M. L., P. L. Earl, K. Gargnoli, S. Picciafuoco, F. Giombini, F. Wong-Stall, and G. Franchini. 1989. Identification of the fusion peptide of primate immunodeficiency viruses. Science. 244:694-697.
7. Gordon, L. M., C. C. Curtain, Y. C. Zhong, A. Kirkpatrick, P. W. Mobley, and A. J. Waring. 1992. The amino-terminal peptide of HIV-1 glycoprotein-41 interacts with human erythrocyte-membranes - peptide conformation, orientation and aggregation. Biochim. Biophys. Acta. 1139:257-274.
8. Slepushkin, V. A., S. M. Andreev, M. V. Sidorova, G. B. Melikyan, V. B. Grigoriev, V. M. Chumakov, A. E. Grinfeldt, R. A. Manukyan, and E. V. Karamov. 1992. Investigation of human-immunodeficiency-virus fusion peptides - analysis of interrelations between their structure and function. AIDS Res. Hum. Retroviruses. 8:9-18.
9. Freed, E. O., E. L. Delwart, G. L. Buchschacher, and A. T. Panganiban. 1992. A mutation in the human-immunodeficiency-virus type-1 transmembrane glycoprotein-gp41 dominantly interferes with fusion and infectivity. Proc. Natl. Acad. Sci. USA. 89:70-74.
10. Mobley, P. W., A. J. Waring, M. A. Sherman, and L. M. Gordon. 1999. Membrane interactions of the synthetic N-terminal peptide of HIV-1 gp41 and its structural analogs. Biochim. Biophys. Acta. 1418:1-18.
11. Jahn, R., and T. C. Sudhof. 1999. Membrane fusion and exocytosis. Annu. Rev. Biochem. 68:863-911.
12. Chernomordik, L. V., and M. M. Kozlov. 2003. Lipid intermediates in membrane fusion: formation, structure, and decay of hemifusion diaphragm. Annu. Rev. Biochem. 72:175-207.
13. Tamm, L. K., J. Crane, and V. Kiessling. 2003. Membrane fusion: a structural perspective on the interplay of lipids and proteins. Curr. Opin. Struct. Biol. 13:453-466.
14. Kuzmin, P. I., J. Zimmerberg, Y. A. Chizmadzhev, and F. S. Cohen. 2001. A quantitative model for membrane fusion based on low-energy intermediate. Proc. Natl. Acad. Sci. USA. 98:7235-7240.
15. Cohen, F. S., and G. B. Melikyan. 2004. The energetics of membrane fusion from binding, through hemifusion, pore formation, and pore enlargement. J. Membr. Biol. 199:1-14.
16. Chernomordik, L. V., J. Zimmerberg, and M. M. Kozlov. 2006. Membranes of the world unite! J. Cell Biol. 175:201-207.
17. Malinin, V. S., and B. R. Lentz. 2004. Energetics of vesicle fusion intermediates: comparison of calculations with observed effects of osmotic and curvature stresses. Biophys. J. 86:2951-2964.
18. Lentz, B. R., D. P. Siegel, and V. Malinin. 2002. Filling potholes on the path to fusion pores. Biophys. J. 82:555-557.
19. Kozlovsky, Y., and M. M. Kozlov. 2002. Stalk model of membrane fusion: solution of energy crisis. Biophys. J. 82:882-895.
20. Markin, V. S., and J. P. Albanesi. 2002. Membrane fusion: stalk model revisited. Biophys. J. 82:693-712.
21. Kozlovsky, Y., A. Efrat, D. P. Siegel, and M. M. Kozlov. 2004. Stalk phase formation: effects of dehydration and saddle splay modulus. Biophys. J. 87:2508-2521.
22. Yang, L., and H. W. Huang. 2002. Observation of a membrane fusion intermediate structure. Science. 297:1877-1879.
23. Chernomordik, L. V., and M. M. Kozlov. 2005. Membrane hemifusion: crossing a chasm in two leaps. Cell. 123:375-382.
24. Liu, Y., and J. F. Nagle. 2004. Diffuse scattering provides material parameters and electron density profiles of biomembranes. Phys. Rev. E. 69:040901.
25. Kučerka, N., Y. Liu, N. Chu, H. I. Petrache, S. Tristram-Nagle, and J. F. Nagle. 2005a. Structure of fully hydrated fluid phase DMPC and DLPC lipid bilayers using x-ray scattering from oriented multilamellar arrays and from unilamellar vesicles. Biophys. J. 88:1-12.
26. Kučerka, N., S. Tristram-Nagle, and J. F. Nagle. 2005b. Structure of fully hydrated fluid phase lipid bilayers with monounsaturated chains. J. Membr. Biol. 208:193-202.
27. Kučerka, N., S. Tristram-Nagle, and J. F. Nagle. 2006. Closer look at structure of fully hydrated fluid phase DPPC bilayers. Biophys. J. 90:L83-L85.
28. Hristova, K., W. W. Wimley, V. K. Mishra, G. M. Anantharamiah, J. P. Segrest, and S. H. White. 1999. An amphipathic alpha-helix at a membrane interface: a structural study using a novel x-ray diffraction method. J. Mol. Biol. 290:99-117.
29. Huang, H. W., and Y. Wu. 1991. Lipid-alamethicin interactions in-fluence alamethicin orientation. Biophys. J. 60:1079-1087.
30. Bradshaw, J. P., M. J. M. Darkes, J. Katsaras, and R. M. Epand. 2000. Neutron diffraction studies of viral fusion peptides. Physica B. 276-278:495-498.
31. Tristram-Nagle, S., R. Zhang, R. M. Suter, C. R. Worthington, W.-J. Sun, and J. F. Nagle. 1993. Measurement of chain tilt angle in fully hydrated bilayers of gel phase lecithins. Biophys. J. 64:1097-1109.
32. Tristram-Nagle, S. 2007. Preparation of oriented, fully hydrated lipids samples for structure determination using x-ray scattering. In Methods in Molecular Biology, Vol. 400: Methods in Membrane Lipids. A. M. Dopico, editor. Humana Press, Totowa, NJ. 63-75.
33. Lyatskaya, Y., Y. Liu, S. Tristram-Nagle, J. Katsaras, and J. F. Nagle. 2001. Method for obtaining structure and interactions from oriented lipid bilayers. Phys. Rev. E. 63:0119071-0119079.
34. DeGennes, P. G., and J. Prost. 1995. The Physics of Liquid Crystals. Oxford University Press, New York.
35. Petrache, H. I., N. Gouliaev, S. Tristram-Nagle, R. Zhang, R. M. Suter, and J. F. Nagle. 1998. Interbilayer interactions from high-resolution x-ray scattering. Phys. Rev. E. 57:7014-7024.
36. Rand, R. P., and V. A. Parsegian. 1989. Hydration forces between phospholipid bilayers. Biochim. Biophys. Acta. 988:351-376.
37. Chu, N., N. Kučerka, Y. Liu, S. Tristram-Nagle, and J. F. Nagle. 2005. Anomalous swelling of lipid bilayer stacks is caused by softening of the bending modulus. Phys. Rev. E. 71:041904.
38. Rawicz, W., K. C. Olbrich, T. J. McIntosh, D. Needham, and E. Evans. 2000. Effect of chain length and unsaturation on elasticity of lipid bilayers. Biophys. J. 79:328-339.
39. Parsegian, V. A. 2006. Van der Waals Forces. Cambridge University Press, New York.
40. Helfrich, W. 1973. Elastic properties of lipid bilayers - theory and possible experiments. Z. Naturforsch. 28:693-703.
41. McIntosh, T. J., and S. A. Simon. 1996. Adhesion between phosphatidylethanolamine bilayers. Langmuir. 12:1622-1630.
42. Petrache, H. I., S. Tristram-Nagle, K. Gawrisch, D. Harries, V. A. Parsegian, and J. F. Nagle. 2004. Structure and fluctuations of charged phosphatidylserine bilayers in the absence of salt. Biophys. J. 86:1574-1586.
43. Podgornik, R., and V. A. Parsegian. 1992. Thermal mechanical fluctuations of fluid membranes in confined geometries - the case of soft confinement. Langmuir. 8:557-562.
44. Hamburger, A. E., S. Kim, B. D. Welch, and M. S. Kay. 2005. Steric accessibility of the HIV-1 gp41 N-trimer region. J. Biol. Chem. 280:12567-12572.
45. Epand, R. M., and R. F. Epand. 2000. Modulation of membrane curvature by peptides. Biopolymers. 55:358-363.