Toxic epidermal necrolysis as a dermatological manifestation of drug hypersensitivity syndrome

European Journal of Dermatology

Volumn 17, Issue 5, 2007, Pages 422-427

  Petkov, Todor ^a   Pehlivanov, Georgy ^a   Grozdev, Ivan ^a   Kavaklieva, Svetlana ^a   Tsankov, Nikolai ^a  

^a MEDICAL UNIVERSITY OF SOFIA   (Bulgaria)

Author keywords

Drug hypersensitivity syndrome; Toxic epidermal necrolysis

Indexed keywords

ANTIBIOTIC AGENT; ANTICONVULSIVE AGENT; CARBAMAZEPINE; CORTICOSTEROID; LAMOTRIGINE; OMEPRAZOLE; PHENOBARBITAL; PHENYTOIN; SALAZOSULFAPYRIDINE; VALPROIC ACID;

ADULT; ARTICLE; CASE REPORT; CLINICAL FEATURE; DRUG HYPERSENSITIVITY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MALE; RASH; SIDE EFFECT; SKIN BIOPSY; TOXIC EPIDERMAL NECROLYSIS;

ADULT; ANTICONVULSANTS; CARBAMAZEPINE; DRUG COMBINATIONS; DRUG HYPERSENSITIVITY; EOSINOPHILIA; EPIDERMAL NECROLYSIS, TOXIC; FEVER; GASTROINTESTINAL AGENTS; GLUCOSAMINE; HUMANS; LIVER DISEASES; LUNG DISEASES; MALE; OMEPRAZOLE; SKIN; SULFASALAZINE; TRIAZINES;

EID: 34548726136     PISSN: 11671122     EISSN: None     Source Type: Journal    
DOI: 10.1684/ejd.2007.0241     Document Type: Article

References (34)

1. Handfield-Jones SE, Jenkins RE, Whittaker SJ, Besse CP, McGibbon DH. The anticonvulsant hypersensitivity syndrome. Br J Dermatol 1993; 129: 175-7.
2. Schaub N, Bircher AJ. Severe hypersensitivity syndrome to lamotrigine confirmed by lymphocyte stimulation in vitro. Allergy 2000; 55: 191-3.
3. Sullivan JR, Neuman IM, Snear HN. The drug hypersensitivity syndrome and Lamotrigine. Aust J Dermatol 2001; 42(suppl. 1): A23.
4. Deandel PY, Traisac T, Rainfray M, et al. Drug hypersensitivity Syndrome with Lamotrigine two cases in elderly. Press Med 2005; 34(7): 516-8.
5. Rieder MJ, Uetrcht J, Shear NH, Cannon M, Miller M, Spielberg SP. Diagnosis of sulfonamide hypersensitivity reactions by in-vitro 'rechallenge' with hydroxylamine metabolites. Ann Intern Med 1989; 110: 286-9.
6. Prussick R, Shear NH. Dapsone hypersensitivity syndrome. J Am Acad Dermatol 1996; 35: 346-9.
7. Knowles SR, Shapiro L, Shear NH. Serious adverse drug reactions induced by minocycline. Report of 13 patients and review of the literature. Arch Dermatol 1996; 132: 934-9.
8. Gupta AK, Kopstein JB, Shear NH. Hypersensitivity reaction to terbinafine. J Am Acad Dermatol 1997; 36: 101 8-9.
9. Knowles SR, Gupta AK, Shear NH, Sauder S. Azathioprine hypersensitivity-like reactions - a case report and review of the literature. Clin Exp Dermatol 1995; 20: 353-6.
10. Arellano F, Sacristan JA. Allopurinol hypersensitivity syndrome: a review. Ann Pharmacother 1993; 19: 337-43.
11. Chaiken BH, Goldberg BI, Segal JP. Dilantin sensitivity; report of a case of hepatitis with jaundice, pyrexia and exfoliative dermatitis. N Engl J Med 1950; 242(23): 897-8.
12. Bocquel H, Bagot M, Roujeau JC. Drug induced pseudolymphoma and drug hypersensitivity (drug rash with eosinophilia and systemic symptoms). Semin Cutan Med Surg 1996; 15: 250-5.
13. Vittorio CC, Muglia JJ. Anticonvulsant hypersensitivity syndrome. Arch Intern Med 1995; 155: 2285-90.
14. Fattinger K, Roos M, Vergeres P, et al. Epidemiology of drug exposure and adverse drug reactions in two Swiss departments of internal medicine. Br J Clin Pharmacol 2000; 49: 158-67.
15. Teo YL, Tay YK, Tan CH, et al. Presumed Dapson - induced drug hypersensitivity syndrome causing reversible hypersensitivity myocarditis and thyrotoxicosis. Ann Acad Med 2006; 35(11): 833-6.
16. Kaminski A, Moreno M, Diaz M, et al. Anticonvulsant hypersensitivity syndrome. Int J Dermatol 2005; 44: 594-8.
17. Gupta A, Eggo M, Uetrecht J, et al. Drug-induced hypothyroidism: the thyroid as a target organ in hypersensitivity reactions to anticonvulsants and sulfonamides. Clin Pharmacol Ther 1992; 5: 56-67.
18. Shear NH, Spielberg SP. Anticonvulsant hypersensitivity syndrome: in vitro assessment of risk. J Clin Invest 1988; 82: 1826-32.
19. Syn WK, Naibitt DJ, Holt AP, Pirmohamed M, Mutimer DJ. Carbamazepine-induced acute liver failure as part of the DRESS syndrome. Int J Clin Pract 2005; 59(8): 988-91.
20. Boccara O, Valeyrie-Allanore L, Crickx B, Descamps V. Association of hypogammaglobulinemia with DRESS (Drug Rash with Eosinophilia and Systemic Symptoms). Eur J Dermatol 2006; 16(6): 666-8.
21. Kano Y, Inaoka M, Shiohara T. Association between anticonvulsant hypersensitivity syndrome and human herpsevirus 6 reactivation and hypergammaglobulinemia. Arch Dermatol 2004; 140: 183-8.
22. Tohyama M, Yahata Y, Yasukama H, et al. Severe hypersensitivity syndrome due to sulfasalazine associated with reactivation of human herpsevirus 6. Arch Dermatol 1998; 134: 1113-7.
23. Suzuki Y, Ihagi R, Aono T. Human herpesvirus infection as a risk factor for the development of severe drug induced hypersensitivity syndrome. Arch Dermatol 1998; 134: 1108-12.
24. Descanp V, Valance A, Edlinger C, et al. Association of human herpesvirus 6 infection with drug reaction with eosinophilia and systemic symptoms. Arch Dermatol 2001; 137: 301-6.
25. Rzany B, Correia O, Kelly JP, Naldi L, Anquier A, Stern R. Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis during first weeks of antiepileptic therapy: a case-control study. Study group of the International Case Control Study on Severe Cutaneous Adverse Reactions. Lancet 1999; 353: 2190-4.
26. Jones M, Fernandez-Herrera J, Dorado JM, et al. Epicutaneous test in carbamazepine cutaneous reactions. Dermatology 1994; 188: 18-20.
27. Bastuji-Garin S, Rzany B, Stern R, et al. Clinical classification of cases of toxic epidermal necrolysis, Stevens-Johnson syndrome, and erythema multiforme. Arch Dermatol 1993; 129: 92-6.
28. Wolf R, Matz H, Marcos B, Orion E. Drug rash with eosinophilia and systemic symptoms vs toxic epidermal necrolysis: the dilemma of classification. Clin Dermatol 2005; 23: 311-4.
29. Chopra S, Levell NJ, Cowley G, et al. Systemic corticosteroids in the pnenytoin hypersensitivity syndrome. Br J Dermatol 1996; 134: 1109-12.
30. Fremia ML. Use of silver sulfadiazine in Stevens-Johnson syndrome. Ann Pharmacother 1994; 28: 736.
31. Casacci M, Lebas D, Decamps F, Fourrier F, Delaporte E. Toxic epidermal necrolysis due to omeprazole. Eur J Dermatol 2006; 16(6): 699-700.
32. Brown T, Apple J, Kasteler J, et al. Hypersensitive reaction in a child due to lamotrigine. Pediatr Dermatol 1999; 16: 46-9.
33. Nori S, Nebesio C, Brashear R, et al. Moxifloxacin - Associated drug hypersensitivity syndrome with toxic epidermal necrolysis and fulminant hepatic failure. Arch Dermatol 2004; 140: 1537-8.
34. Redondo P, de Felipe I, de la Pena A, et al. Drug induced hypersensitivity syndrome and toxic epidermal necrolysis. Treatment with N-acetylcysteine. Br J Dermatol 1997; 136(4): 645-6.