Iron absorption by Belgrade rat pups during lactation

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 293, Issue 3, 2007, Pages

  Thompson, Khristy ^a   Molina, Ramon M ^a   Donaghey, Thomas ^a   Brain, Joseph D ^a   Wessling Resnick, Marianne ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Belgrade rat; DMT1; Iron transport; Lactation

Indexed keywords

FERRIC CHLORIDE; HEME; RADIOISOTOPE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW; FEMALE; GENE MUTATION; HEART; INTESTINE; INTESTINE ABSORPTION; IRON ABSORPTION; IRON BLOOD LEVEL; IRON METABOLISM; KIDNEY PARENCHYMA; LACTATION; LIVER; MALE; MILK; NEWBORN; NEWBORN PERIOD; NONHUMAN; PRIORITY JOURNAL; RAT; SKELETAL MUSCLE; SPLEEN; STOMACH; TISSUE DISTRIBUTION; WEANING;

AGING; ANIMALS; ANIMALS, NEWBORN; CATION TRANSPORT PROTEINS; DUODENUM; FEMALE; FERRIC COMPOUNDS; INTESTINAL ABSORPTION; INTUBATION, GASTROINTESTINAL; IRON RADIOISOTOPES; LACTATION; MALE; MUTATION; RATS; RATS, INBRED F344; RATS, MUTANT STRAINS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION; WEANING;

EID: 34548710906     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00153.2007     Document Type: Article

References (36)

1. Bowen BJ, Morgan EH. Anemia of the Belgrade rat: evidence for defective membrane transport of iron. Blood 70: 38-44, 1987.
2. Canonne-Hergaux F, Gruenheid S, Ponka P, Gros P. Cellular and subcellular localization of the Nramp2 iron transporter in the intestinal brush border and regulation by dietary iron. Blood 93: 4406-4417, 1999.
3. Chowrimootoo G, Gillett M, Debnam ES, Srai SK, Epstein O. Iron-transferrin binding to isolated guinea pig enterocytes and the regional localisation of intestinal iron transfer during ontogeny. Biochim Biophys Acta 1116: 256-260, 1992.
4. Chua AC, Morgan EH. Manganese metabolism is impaired in the Belgrade laboratory rat. J Comp Physiol [B] 167: 361-369, 1997.
5. Davidson LA, Lonnerdal B. Specific binding of lactoferrin to brush-border membrane: ontogeny and effect of glycan chain. Am J Physiol Gastrointest Liver Physiol 254: G580-G585, 1988.
6. Diluzio NR, Zilversmit DB. Influence of exogenous proteins on blood clearance and tissue distribution of colloidal gold. Am J Physiol 180: 563-565, 1955.
7. Edwards J, Huebers H, Kunzler C, Finch C. Iron metabolism in the Belgrade rat. Blood 67: 623-628, 1986.
8. Edwards JA, Sullivan AL, Hoke JE. Defective delivery of iron to the developing red cell of the Belgrade laboratory rat. Blood 55: 645-648, 1980.
9. Eide D, Broderius M, Fett J, Guerinot ML. A novel iron-regulated metal transporter from plants identified by functional expression in yeast. Proc Natl Acad Sci USA 93: 5624-5628, 1996.
10. Farcich EA, Morgan EH. Diminished iron acquisition by cells and tissues of Belgrade laboratory rats. Am J Physiol Regul Integr Comp Physiol 262: R220-R224, 1992.
11. Fleming MD, Romano MA, Su MA, Garrick LM, Garrick MD, Andrews NC. Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport. Proc Natl Acad Sci USA 95: 1148-1153, 1998.
12. Garrick M, Scott D, Walpole S, Finkelstein E, Whitbred J, Chopra S, Trivikram L, Mayes D, Rhodes D, Cabbagestalk K, Oklu R, Sadiq A, Mascia B, Hoke J, Garrick L. Iron supplementation moderates but does not cure the Belgrade anemia. Biometals 10: 65-76, 1997.
13. Garrick MD, Gniecko K, Liu Y, Cohan DS, Garrick LM. Transferrin and the transferrin cycle in Belgrade rat reticulocytes. J Biol Chem 268: 14867-14874, 1993.
14. Grass G, Franke S, Taudte N, Nies DH, Kucharski LM, Maguire ME, Rensing C. The metal permease ZupT from Escherichia coli is a transporter with a broad substrate spectrum. J Bacteriol 187: 1604-1611, 2005.
15. Gunshin H, Fujiwara Y, Custodio AO, Direnzo C, Robine S, Andrews NC. Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver. J Clin Invest 115: 1258-1266, 2005.
16. Iyer S, Lonnerdal B. Lactoferrin, lactoferrin receptors and iron metabolism. Eur J Clin Nutr 47: 232-241, 1993.
17. Kawakami H, Dosako S, Lonnerdal B. Iron uptake from transferrin and lactoferrin by rat intestinal brush-border membrane vesicles. Am J Physiol Gastrointest Liver Physiol 258: G535-G541, 1990.
18. Kawakami H, Lonnerdal B. Isolation and function of a receptor for human lactoferrin in human fetal intestinal brush-border membranes. Am J Physiol Gastrointest Liver Physiol 261: G841-G846, 1991.
19. Knopfel M, Zhao L, Garrick MD. Transport of divalent transition-metal ions is lost in small-intestinal tissue of b/b Belgrade rats. Biochemistry 44: 3454-3465, 2005.
20. Leong WI, Bowlus CL, Tallkvist J, Lonnerdal B. DMT1 and FPN1 expression during infancy: developmental regulation of iron absorption. Am J Physiol Gastrointest Liver Physiol 285: G1153-G1161, 2003.
21. Leong WI, Bowlus CL, Tallkvist J, Lonnerdal B. Iron supplementation during infancy-effects on expression of iron transporters, iron absorption, and iron utilization in rat pups. Am J Clin Nutr 78: 1203-1211, 2003.
22. Liuzzi JP, Aydemir F, Nam H, Knutson MD, Cousins RJ. Zip14 (Slc39a14) mediates non-transferrin-bound iron uptake into cells. Proc Natl Acad Sci USA 103: 13612-13617, 2006.
23. Lonnerdal B. Effects of milk and milk components on calcium, magnesium, and trace element absorption during infancy. Physiol Rev 77: 643-669, 1997.
24. Lopez V, Suzuki YA, Lonnerdal B. Ontogenic changes in lactoferrin receptor and DMT1 in mouse small intestine: implications for iron absorption during early life. Biochem Cell Biol 84: 337-344, 2006.
25. McMillan JA, Oski FA, Lourie G, Tomarelli RM, Landaw SA. Iron absorption from human milk, simulated human milk, and proprietary formulas. Pediatrics 60: 896-900, 1977.
26. Morgan EH, Oates PS. Mechanisms and regulation of intestinal iron absorption. Blood Cells Mol Dis 29: 384-399, 2002.
27. Oates PS, Morgan EH. Defective iron uptake by the duodenum of Belgrade rats fed diets of different iron contents. Am J Physiol Gastrointest Liver Physiol 270: G826-G832, 1996.
28. Oates PS, Thomas C, Freitas E, Callow MJ, Morgan EH. Gene expression of divalent metal transporter 1 and transferrin receptor in duodenum of Belgrade rats. Am J Physiol Gastrointest Liver Physiol 278: G930-G936, 2000.
29. Oates PS, Thomas C, Morgan EH. Transferrin receptor activity and localisation in the rat duodenum. Pflügers Arch 440: 116-124, 2000.
30. Saarinen UM, Siimes MA, Dallman PR. Iron absorption in infants: high bioavailability of breast milk iron as indicated by the extrinsic tag method of iron absorption and by the concentration of serum ferritin. J Pediatr 91: 36-39, 1977.
31. Sladic-Simic D, Martinovitch PN, Zivkovic N, Pavic D, Martinovic J, Kahn M, Ranney HM. A thalassemia-like disorder in Belgrade laboratory rats. Ann NY Acad Sci 165: 93-99, 1969.
32. Takeuchi T, Jyonotsuka T, Kamemori N, Kawano G, Shimizu H, Ando K, Harada E. Enteric-formulated lactoferrin was more effectively transported into blood circulation from gastrointestinal tract in adult rats. Exp Physiol 91: 1033-1040, 2006.
33. Thompson K, Molina RM, Brain JD, Wessling-Resnick M. Belgrade rats display liver iron loading. J Nutr 136: 3010-3014, 2006.
34. Vert G, Briat JF, Curie C. Arabidopsis IRT2 gene encodes a root-periphery iron transporter. Plant J 26: 181-189, 2001.
35. Ward PP, Mendoza-Meneses M, Cunningham GA, Conneely OM. Iron status in mice carrying a targeted disruption of lactoferrin. Mol Cell Biol 23: 178-185, 2003.
36. Wu CC, Yates JR 3rd, Neville MC, Howell KE. Proteomic analysis of two functional states of the Golgi complex in mammary epithelial cells. Traffic 1: 769-782, 2000.