Acromegaly associated with type 2 diabetes showing normal IGF-1 levels under poorly controlled glycemia

Endocrine Journal

Volumn 54, Issue 4, 2007, Pages 537-541

  Lim, Dong Jun ^a   Kwon, Hyuk Sang ^a,b   Cho, Jae Hyoung ^a   Kim, Sang Hee ^a   Choi, Yoon Hee ^a   Yoon, Kun Ho ^a   Cha, Bong Yun ^a   Lee, Kwang Woo ^a   Son, Ho Young ^a   Kang, Sung Koo ^a  

^a The Catholic University of Korea   (South Korea)

^b The Catholic University of Korea   (South Korea)

Author keywords

Acromegaly; Growth Hormone (GH); Insulin like Growth Factor 1 (IGF 1); Type 2 diabetes

Indexed keywords

GLUCOSE; GROWTH HORMONE; INSULIN; SOMATOMEDIN C;

ACROMEGALY; AGED; ARTICLE; BODY MASS; CASE REPORT; CLINICAL FEATURE; DISEASE ASSOCIATION; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; GLYCEMIC CONTROL; HORMONE DETERMINATION; HUMAN; LABORATORY TEST; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NUCLEAR MAGNETIC RESONANCE IMAGING;

ACROMEGALY; ADENOMA; AGED; DIABETES MELLITUS, TYPE 2; HUMAN GROWTH HORMONE; HUMANS; HYPERGLYCEMIA; INSULIN-LIKE GROWTH FACTOR I; MAGNETIC RESONANCE IMAGING; MALE; PITUITARY NEOPLASMS;

EID: 34548701561     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.K06-083     Document Type: Article

References (16)

1. AACE Acromegaly Guidelines Taskforce (2004) AACE Medical guidelines for clinical practice for the diagnosis and treatment of acromegaly. Endocr Pract 10: 213-225.
2. th ed., New York, McGraw-Hill, vol. 2: 2076-2097.
3. Monzavi R, Cohen P (2002) IGFs and IGFBPs: role in health and disease. Best Pract Res Clin Endocrinol Metab 16: 433-447.
4. Clayton KL, Holly JM, Carlsson LM, Jones J, Cheetham TD, Taylor AM, Dunger DB (1994) Loss of the normal relationships between growth hormone, growth hormone-binding protein and insulin-like growth factor-1 in adolescents with insulin-dependent diabetes mellitus. Clin Endocrinol 41: 517-524.
5. Horner JM, Kemp SF, Hintz RL (1981) Growth hormone and somatomedin in insulin-dependent diabetes mellitus. J Clin Endocrinol Metab 53: 1148-1153.
6. Wurzburger MI, Sonksen PH (1996) Natural course of growth hormone hypersecretion in insulin-dependent diabetes mellitus. Med Hypotheses 46: 145-149.
7. Tan K, Baxter RC (1986) Serum insulin-like growth factor I levels in adult diabetic patients: the effect of age. J Clin Endocrinol Metab 63: 651-655.
8. Clemmons DR, Van Wyk JJ, Ridgway EC, Kliman B, Kjellberg N, Underwood LE (1979) Evaluation of acromegaly by radioimmunoassay of somatomedin-C. N Engl J Med 301: 1138-1142.
9. Grottoli S, Gasco V, Ragazzoni F, Ghigo E (2003) Hormonal diagnosis of GH hypersecretory states. J Endocrinol Invest 26 (Suppl): 27-35.
10. Daughaday WH, Phillips LS, Mueller MC (1976) The effect of insulin and growth hormone on the release of somatomedin by the isolated rat liver. Endocrinology 98: 1214-1219.
11. Sonksen H, Russell-Jones D, Jones RH (1993) Growth hormone and diabetes mellitus. A review of sixty-three years of medical research and a glimpse into the future? Horm Res 40: 68-79.
12. Mercado M, Molitch ME, Baumann G (1992) Low plasma growth hormone binding protein in IDDM. Diabetes 41: 605-609.
13. Kratzsch J, Keliner K, Zilkens T, Schmidt-Gayk H, Selisko T, Scholz GH (1996) Growth hormone-binding protein related immunoreactivity is regulated by the degree of insulinopenia in diabetes mellitus. Clin Endocrinol (Oxf) 44: 673-678.
14. Herlihy OM, Perros P (2000) Elevated serum growth hormone in a patient with Type 1 diabetes: a diagnostic dilemma. Diabetes Metab Res Rev 16: 211-216.
15. Clemmons DR, Klibanski A, Underwood LE, McArthur JW, Ridgway EC, Beitins IZ, Van Wyk JJ (1981) Reduction of plasma immunoreactive somatomedin C during fasting in humans. J Clin Endocrinol Metab 53: 1247-1250.
16. Amiel SA, Sherwin RS, Hintz RL, Gertner JM, Press CM, Tamborlane WV (1984) Effect on diabetes and its control on insulin-like growth factors in the young subject with type I diabetes. Diabetes 33: 1175-1179.