Pain management and the effect of guidelines in neonatal units in Austria, Germany and Switzerland

Pediatrics International

Volumn 49, Issue 5, 2007, Pages 652-658

  Gharavi, Bahman ^a   Schott, Claus ^b   Nelle, Mathias ^a   Reiter, Gernot ^c   Linderkamp, Otwin ^b  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

Analgesia; Guidelines; Pain; Preterm; Questionnaire

Indexed keywords

4 AMINOBUTYRIC ACID; ANALGESIC AGENT; CHLORAL HYDRATE; CLONIDINE; CODEINE; DIAZEPAM; DIPYRONE; ETOMIDATE; FENTANYL; IBUPROFEN; INDOMETACIN; KETAMINE; LORACEPAM; MEPIVACAINE; MIDAZOLAM; MORPHINE; NALBUPHINE; OPIATE; PARACETAMOL; PETHIDINE; PHENOBARBITAL; PIRITRAMIDE; SEDATIVE AGENT; THIOPENTAL; TILIDINE; TRAMADOL; UNCLASSIFIED DRUG;

ARTICLE; AUSTRIA; CONTROLLED STUDY; DOCUMENTATION; GERMANY; GESTATIONAL AGE; HUMAN; MAJOR CLINICAL STUDY; PAIN; PAIN ASSESSMENT; PEDIATRIC HOSPITAL; PEDIATRIC WARD; PRACTICE GUIDELINE; PRIORITY JOURNAL; QUESTIONNAIRE; SWITZERLAND;

ANALGESICS; AUSTRIA; GERMANY; HUMANS; HYPNOTICS AND SEDATIVES; INFANT, NEWBORN; INTENSIVE CARE UNITS, NEONATAL; PAIN; PAIN MEASUREMENT; PRACTICE GUIDELINES AS TOPIC; QUESTIONNAIRES; SWITZERLAND;

EID: 34548695904     PISSN: 13288067     EISSN: 1442200X     Source Type: Journal    
DOI: 10.1111/j.1442-200X.2007.02453.x     Document Type: Article

References (42)

1. Barker DP, Rutter N. Exposure to invasive procedures in neonatal intensive care unit admissions. Arch. Dis. Child. Fetal Neonatal Ed. 1995 72 : F47 8.
2. Simons SH, van Dijk M, Anand KS, Roofthooft D, van Lingen RA, Tibboel D. Do we still hurt newborn babies? A prospective study of procedural pain and analgesia in neonates. Arch. Pediatr. Adolesc. Med. 2003 157 : 1058 64.
3. Anand KJ, Carr DB. The neuroanatomy, neurophysiology, and neurochemistry of pain, stress, and analgesia in newborns and children. Pediatr. Clin. North Am. 1989 36 : 795 822.
4. Fitzgerald M, Anand KJS. Development neuroanatomy and neurophysiology of pain. In : Schlechter NL, Berde CB, Yaster M (eds). Pain in Infants, Children and Adolescents. MD Williams and Wilkins, Baltimore, 1993 11 31.
5. Anand KS, Grunau RE, Oberlander TF. Developmental character and long-term consequences of pain in infants and children. Child. Adolesc. Psychiatr. Clin. N. Am. 1997 6 : 703 24.
6. Grunau RV, Whitfield MF, Petrie JH, Fryer EL. Early pain experience, child and family factors, as precursors of somatization: A prospective study of extremely premature and fullterm children. Pain 1994 56 : 353 9.
7. Porter FL, Grunau RE, Anand KJ. Long-term effects of pain in infants. J. Dev. Behav. Pediatr. 1999 20 : 253 61.
8. Schechter NL. The undertreatment of pain in children: An overview. Pediatr. Clin. North Am. 1989 36 : 781 94.
9. Anand KJS, Selanikio JD SOPAIN Study Group. Routine analgesic practices in 109 neonatal intensive care units. Pediatr. Res. 1996 39 : 191A 2A.
10. Bauchner H, May A, Coates E. Use of analgesic agents for invasive medical procedures in pediatric and neonatal intensive care units. J. Pediatr. 1992 121 : 647 9.
11. Franck LS. A national survey of the assessment and treatment of pain and agitation in the neonatal intensive care unit. J. Obstet. Gynecol. Neonatal Nurs. 1987 16 : 387 93.
12. Porter FL, Wolf CM, Gold J, Lotsoff D, Miller JP. Pain and pain management in newborn infants: A survey of physicians and nurses. Pediatrics 1997 100 : 626 32.
13. Tohill J, McMorrow O. Pain relief in neonatal intensive care. Lancet 1990 336 : 569.
14. Fernandez CV, Rees EP. Pain management in Canadian level 3 neonatal intensive care units. CMAJ 1994 50 : 499 504.
15. Johnston CC, Collinge JM, Henderson SJ, Anand KJ. A cross-sectional survey of pain and pharmacological analgesia in Canadian neonatal intensive care units. Clin. J. Pain 1997 13 : 308 12.
16. Debillon T, Bureau V, Savagner C, Zupan-Simunek V, Carbajal R. Pain management in French neonatal intensive care units. Acta Paediatr. 2002 91 : 822 6.
17. Porter FL, Wolf CM, Miller JP. Procedural pain in newborn infants: The influence of intensity and development. Pediatrics 1999 104 : e13.
18. Johnston CC, Stevens B, Craig KD, Grunau RV. Developmental changes in pain expression in premature, full-term, two- and four-month-old infants. Pain 1993 52 : 201 8.
19. Johnston CC, Stevens BJ, Yang F, Horton L. Differential response to pain by very premature neonates. Pain 1995 61 : 471 9.
20. Majnemer A, Rosenblatt B, Willis D, Lavallee J. The effect of gestational age at birth on somatosensory-evoked potentials performed at term. J. Child Neurol. 1990 5 : 329 35.
21. Allegaert K, Tibboel D, Naulaers G et al. Systematic evaluation of pain in neonates: Effect on the number of intravenous analgesics prescribed. Eur. J. Clin. Pharmacol. 2003 59 : 87 90.
22. Anand KJ International Evidence-Based Group for Neonatal Pain. Consensus statement for the prevention and management of pain in the newborn. Arch. Pediatr. Adolesc. Med. 2001 155 : 173 80.
23. Acharya AB, Annamali S, Taub NA, Field D. Oral sucrose analgesia for preterm infant venepuncture. Arch. Dis. Child. Fetal Neonatal Ed. 2004 89 : F17 F18.
24. Bucher HU, Moser T, von Siebenthal K, Keel M, Wolf M, Duc G. Sucrose reduces pain reaction to heel lancing in preterm infants: A placebo-controlled, randomised and masked study. Pediatr. Res. 1995 38 : 332 5.
25. Carbajal R, Chauvet X, Courdec S, Olivier-Martin M. Randomized trial of analgesic effects of sucrose, glucose, and pacifiers in term neonates. BMJ 1999 319 : 1397 402.
26. Johnston CC, Stremler R, Horton L, Friedman A. Effect of repeated doses of sucrose during heel stick procedure in preterm neonates. Biol. Neonate 1999 75 : 160 66.
27. Guinsburg R, Kopelman BI, Anand KJ, de Almeida MF, Peres Cde A, Miyoshi MH. Physiological, hormonal, and behavioral responses to a single fentanyl dose in intubated and ventilated preterm neonates. J. Pediatr. 1998 132 : 954 9.
28. Saarenmaa E, Neuvonen PJ, Fellman V. Gestational age and birth weight effects on plasma clearance of fentanyl in newborn infants. J. Pediatr. 2000 136 : 767 70.
29. Saarenmaa E, Neuvonen PJ, Rosenberg P, Fellman V. Morphine clearance and effects in newborn infants in relation to gestational age. Clin. Pharmacol. Ther. 2000 68 : 160 66.
30. Scott CS, Riggs KW, Ling EW et al. Morphine pharmacokinetics and pain assessment in premature newborns. J. Pediatr. 1999 135 : 423 9.
31. Pokela ML, Olkkola KT, Koivisto M, Ryhanen P. Pharmacokinetics and pharmacodynamics of intravenous meperidine in neonates and infants. Clin. Pharmacol. Ther. 1992 52 : 342 9.
32. Pokela ML. Overdoses of pethidine given to two preterm neonates. Acta Paediatr. 1997 86 : 323 5.
33. Anderson BJ, van Lingen RA, Hansen TG, Lin YC, Holford NH. Acetaminophen developmental pharmacokinetics in premature neonates and infants: A pooled population analysis. Anesthesiology 2002 96 : 1336 45.
34. Lin YC, Sussman HH, Benitz WE. Plasma concentrations after rectal administration of acetaminophen in preterm neonates. Paediatr. Anaesth. 1997 7 : 457 9.
35. van Lingen RA, Deinum HT, Quak CM, Okken A, Tibboel D. Multiple-dose pharmacokinetics of rectally administered acetaminophen in term infants. Clin. Pharmacol. Ther. 1999 66 : 509 15.
36. Sharma PK, Garg SK, Narang A. Pharmacokinetics of oral ibuprofen in premature infants. J. Clin. Pharmacol. 2003 43 : 968 73.
37. Mayers DJ, Hindmarsh KW, Sankaran K, Gorecki DK, Kasian GF. Chloral hydrate disposition following single-dose administration to critically ill neonates and children. Dev. Pharmacol. Ther. 1991 16 : 71 7.
38. Reimche LD, Sankaran K, Hindmarsh KW, Kasian GF, Gorecki DK, Tan L. Chloral hydrate sedation in neonates and infants: Clinical and pharmacologic considerations. Dev. Pharmacol. Ther. 1989 12 : 57 64.
39. Anand KJS, McIntosh N, Lagercrantz H, Pelausa E, Young TE, Vasa R. Analgesia and sedation in preterm neonates who require ventilatory support: Results from the NOPAIN trial. Arch. Pediatr. Adolesc. Med. 1999 153 : 331 8.
40. Ng E, Taddio A, Ohlsson A. Intravenous midazolam infusion for sedation of infants in the neonatal intensive care unit (Cochrane Review). Cochrane Library, Issue 2. Update Software, Oxford, 2002.
41. Bittigau P, Sifringer M, Ikonomidou C. Antiepileptic drugs and apoptosis in the developing brain. Ann. N.Y. Acad. Sci. 2003 993 : 103 14 discussion 123-4.
42. Kahn DJ, Richardson DK, Gray JE et al. Variation among neonatal intensive care units in narcotic administration. Arch. Pediatr. Adolesc. Med. 1998 152 : 844 51.