Down-Regulation of Matrix Metalloproteinase-9 (MMP-9) Expression in the Myocardium of Congestive Heart Failure Patients

Transplantation Proceedings

Volumn 39, Issue 7, 2007, Pages 2344-2346

  Batlle, M ^a   Perez Villa F ^a   Garcia Pras E ^a   Lazaro A ^a   Orus J ^a   Roque M ^a   Roig, E ^a  

^a HOSPITAL CLÍNIC   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; GELATINASE B; INTERSTITIAL COLLAGENASE; MESSENGER RNA; STROMELYSIN;

ADULT; ARTICLE; CLINICAL ARTICLE; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; DOWN REGULATION; FIBROSIS; HEART MUSCLE BIOPSY; HUMAN; ORGAN DONOR; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION;

EID: 34548692092     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2007.06.046     Document Type: Article

References (7)

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2. Ducharme A., Frantz S., Aikawa M., et al. Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction. J Clin Invest 106 (2000) 55
3. Hayashidani S., Tsutsui H., Ikeuchi M., et al. Targeted deletion of MMP-2 attenuates early LV rupture and late remodeling after experimental myocardial infarction. Am J Physiol Heart Circ Physiol 285 (2003) H1229
4. Sakata Y., Yamamoto K., Mano T., et al. Activation of matrix metalloproteinases precedes left ventricular remodeling in hypertensive heart failure rats: its inhibition as a primary effect of Angiotensin-converting enzyme inhibitor. Circulation 109 (2004) 2143
5. Batlle M., Roig E., Perez-Villa F., et al. Increased expression of the renin-angiotensin system and mast cell density but not of angiotensin-converting enzyme II in late stages of human heart failure. J Heart Lung Transplant 25 (2006) 1117
6. Spinale F.G., Coker M.L., Heung L.J., et al. A matrix metalloproteinase induction/activation system exists in the human left ventricular myocardium and is upregulated in heart failure. Circulation 102 (2000) 1944
7. Polyakova V., Hein S., Kostin S., et al. Matrix metalloproteinases and their tissue inhibitors in pressure-overloaded human myocardium during heart failure progression. J Am Coll Cardiol 44 (2004) 1609