Acute effects of vecuronium on pulmonary function and hypoxemic episodes in preterm infants

Pediatrics International

Volumn 49, Issue 5, 2007, Pages 631-636

  McEvoy, Cindy ^a   Sardesai, Smeeta ^b   Schilling, Diane ^a   Durand, Manuel ^b,c  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c WOMEN S AND CHILDREN S HOSPITAL   (United States)

Author keywords

Hypoxemia; Muscle relaxants; Premature infants; Pulmonary mechanics; Vecuronium

Indexed keywords

OXYGEN; VECURONIUM;

ARTICLE; ARTIFICIAL VENTILATION; BIRTH WEIGHT; BLOOD PRESSURE; BREATHING MECHANICS; CLINICAL ARTICLE; DRUG EFFECT; GESTATIONAL AGE; HEART RATE; HUMAN; HYPOXEMIA; INFANT; LUNG COMPLIANCE; LUNG FUNCTION; LUNG RESISTANCE; MUSCLE RELAXATION; OXYGEN CONCENTRATION; PERINATAL PERIOD; PREMATURITY; PRIORITY JOURNAL;

ANOXIA; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; LUNG; NEUROMUSCULAR NONDEPOLARIZING AGENTS; RESPIRATORY FUNCTION TESTS; VECURONIUM BROMIDE;

EID: 34548687945     PISSN: 13288067     EISSN: 1442200X     Source Type: Journal    
DOI: 10.1111/j.1442-200X.2007.02405.x     Document Type: Article

References (26)

1. Greenough A, Morley CJ, Wood S, Davis JA. Pancuronium prevents pneumothoraces in ventilated premature babies who actively expire against positive pressure inflation. Lancet 1984 1 : 1 3.
2. Finer NN, Tomney PM. Controlled evaluation of muscle relaxation in the ventilated neonate. Pediatrics 1981 67 : 641 6.
3. Perlman JM, Goodman S, Kreusser KL, Volpe JJ. Reduction in intraventricular hemorrhage by elimination of fluctuating cerebral blood-flow velocity in preterm infants with respiratory distress syndrome. N. Engl. J. Med. 1985 312 : 1353 7.
4. Bhutani VK, Abbasi S, Sivieri EM. Continuous skeletal muscle paralysis: Effect on neonatal pulmonary mechanics. Pediatrics 1988 81 : 419 22.
5. Bada HS, Burnette TM, Arheart KL, Shull N, Mirro R, Korones SB. Pancuronium attenuates associated hemodynamic and transcutaneous oxygen tension changes during nursery procedures. J. Perinatol. 1995 15 : 119 23.
6. Durand M, McEvoy C, MacDonald K. Spontaneous desaturations in intubated very low birth weight infants with acute and chronic lung disease. Pediatr. Pulmonol. 1992 13 : 136 42.
7. McEvoy C, Durand M, Hewlett V. Episodes of spontaneous desaturations in infants with chronic lung disease at two different levels of oxygenation. Pediatr. Pulmonol. 1993 15 : 140 44.
8. Goldman SL, Bosque E, McCann E, Lewis K. Pulmonary mechanics in premature infants one month after treatment with synthetic surfactant. J. Pediatr. 1992 120 : S25 8.
9. Bhutani VK, Sivieri EM, Abbasi S, Shaffer TH. Evaluation of neonatal pulmonary mechanics and energetics: A two factor least mean square analysis. Pediatr. Pulmonol. 1988 4 : 150 58.
10. Sullivan KJ, Durand M, Chang HK. A forced perturbation method of assessing pulmonary mechanical function in intubated infants. Pediatr. Res. 1991 29 : 82 8.
11. Kugelman A, Durand M, Garg M. Pulmonary effect of inhaled furosemide in ventilated infants with severe bronchopulmonary dysplasia. Pediatrics 1997 99 : 71 5.
12. Durand M, Mendoza ME, Tantivit P, Kugelman A, McEvoy C. A randomized trial of moderately early low-dose dexamethasone therapy in very low birth weight infants: Dynamic pulmonary mechanics, oxygenation, and ventilation. Pediatrics 2002 109 : 262 8.
13. McEvoy C, Mendoza ME, Bowling S, Hewlett V, Sardesai S, Durand M. Prone positioning decreases episodes of hypoxemia in extremely low birth weight infants (1000 grams or less) with chronic lung disease. J. Pediatr. 1997 130 : 305 9.
14. McEvoy C, Sardesai S, Macri C, Paul R, Durand M. Neonatal pulmonary mechanics and oxygenation after prophylactic amnioinfusion in labor: A randomized clinical trial. Pediatrics 1995 95 : 688 92.
15. Firme SRE, McEvoy C, Alconcel C, Tanner J, Durand M. Episodes of hypoxemia during synchronized intermittent mandatory ventilation in ventilator-dependent very low birth weight infants. Pediatr. Pulmonol. 2005 40 : 9 14.
16. Durand M, Sangha B, Cabal LA, Hoppenbrouwers T, Hodgman JE. Cardiopulmonary and intracranial pressure changes related to endotracheal suctioning in preterm infants. Crit. Care Med. 1989 17 : 506 10.
17. Fahey MR, Morris RB, Miller RD, Sohn YJ, Cronnelly R, Gencarelli P. Clinical pharmacology of ORG NC45 (Norcuron): A new nondepolarizing muscle relaxant. Anesthesiology 1981 55 : 6 11.
18. Lee Son S, Waud BE, Waud DR. A comparison of the neuromuscular blocking and vagolytic effects of ORG NC45 and pancuronium. Anesthesiology 1981 55 : 12 18.
19. Martin LD, Bratton SL, O'Rourke PP. Clinical uses and controversies of neuromuscular blocking agents in infants and children. Crit. Care Med. 1999 27 : 1358 68.
20. England SJ. Current techniques for assessing pulmonary function in the newborn and infant: Advantages and limitations. Pediatr. Pulmonol. 1988 4 : 48 53.
21. Burnette TM, Bada HS, Mirro R. Pavulon does not change pulmonary mechanics in the low birth weight infant (Abstract). Clin. Res. 1990 38 : 66A.
22. Stark AR, Bascom R, Frantz ID. Muscle relaxation in mechanically ventilated infants. J. Pediatr. 1979 94 : 439 43.
23. Runkle B, Bancalari E. Acute cardiopulmonary effects of pancuronium bromide in mechanically ventilated newborn infants. J. Pediatr. 1984 104 : 614 17.
24. Froese AB, Bryan AC. Effects of anesthesia and paralysis on diaphragmatic mechanics in man. Anesthesiology 1974 41 : 242 55.
25. Mellins RB, Levine OR, Skalak R, Fishman AP. Interstitial pressure of the lung. Circ. Res. 1969 24 : 197 212.
26. Pollitzer MJ, Reynolds EOR, Shaw DG, Thomas RM. Pancuronium during mechanical ventilation speeds recovery of lungs of infants with hyaline membrane disease. Lancet 1981 1 : 346 8.