-
1
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
Carmeliet P., and Jain R.K. Angiogenesis in cancer and other diseases. Nature 407 (2000) 249-257
-
(2000)
Nature
, vol.407
, pp. 249-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
2
-
-
0037699955
-
Angiogenesis in health and disease
-
Carmeliet P. Angiogenesis in health and disease. Nat Med 9 (2003) 653-660
-
(2003)
Nat Med
, vol.9
, pp. 653-660
-
-
Carmeliet, P.1
-
3
-
-
30744449235
-
Angiogenesis as a therapeutic target
-
Ferrara N., and Kerbel R.S. Angiogenesis as a therapeutic target. Nature 438 (2005) 967-974
-
(2005)
Nature
, vol.438
, pp. 967-974
-
-
Ferrara, N.1
Kerbel, R.S.2
-
4
-
-
0032773566
-
Tumour vasculature as a target for cancer therapy
-
Chaplin D.J., and Dougherty G.J. Tumour vasculature as a target for cancer therapy. Br J Cancer 80 (1999) 57-64
-
(1999)
Br J Cancer
, vol.80
, pp. 57-64
-
-
Chaplin, D.J.1
Dougherty, G.J.2
-
5
-
-
12244292196
-
Differentiation and definition of vascular-targeted therapies
-
Siemann D.W., Bibby M.C., Dark G.G., et al. Differentiation and definition of vascular-targeted therapies. Clin Cancer Res 11 (2005) 416-420
-
(2005)
Clin Cancer Res
, vol.11
, pp. 416-420
-
-
Siemann, D.W.1
Bibby, M.C.2
Dark, G.G.3
-
7
-
-
2642571660
-
Vascular-targeting therapies for treatment of malignant disease
-
Siemann D.W., Chaplin D.J., and Horsman M.R. Vascular-targeting therapies for treatment of malignant disease. Cancer 100 (2004) 2491-2499
-
(2004)
Cancer
, vol.100
, pp. 2491-2499
-
-
Siemann, D.W.1
Chaplin, D.J.2
Horsman, M.R.3
-
8
-
-
0036278972
-
Antitumor activity of the novel vascular targeting agent ZD6126 in a panel of tumor models
-
Blakey D.C., Westwood F.R., Walker M., et al. Antitumor activity of the novel vascular targeting agent ZD6126 in a panel of tumor models. Clin Cancer Res 8 (2002) 1974-1983
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1974-1983
-
-
Blakey, D.C.1
Westwood, F.R.2
Walker, M.3
-
9
-
-
0037115398
-
ZD6126: A novel vascular-targeting agent that causes selective destruction of tumor vasculature
-
Davis P.D., Dougherty G.J., Blakey D.C., et al. ZD6126: A novel vascular-targeting agent that causes selective destruction of tumor vasculature. Cancer Res 62 (2002) 7247-7253
-
(2002)
Cancer Res
, vol.62
, pp. 7247-7253
-
-
Davis, P.D.1
Dougherty, G.J.2
Blakey, D.C.3
-
10
-
-
0036644835
-
Activity of a new vascular targeting agent, ZD6126, in pulmonary metastases by human lung adenocarcinoma in nude mice
-
Goto H., Yano S., Zhang H., et al. Activity of a new vascular targeting agent, ZD6126, in pulmonary metastases by human lung adenocarcinoma in nude mice. Cancer Res 62 (2002) 3711-3715
-
(2002)
Cancer Res
, vol.62
, pp. 3711-3715
-
-
Goto, H.1
Yano, S.2
Zhang, H.3
-
11
-
-
33646063560
-
Tumour overexpression of inducible nitric oxide synthase (iNOS) increases angiogenesis and may modulate the anti-tumour effects of the vascular disrupting agent ZD6126
-
Cullis E.R., Kalber T.L., Ashton S.E., et al. Tumour overexpression of inducible nitric oxide synthase (iNOS) increases angiogenesis and may modulate the anti-tumour effects of the vascular disrupting agent ZD6126. Microvasc Res 71 (2006) 76-84
-
(2006)
Microvasc Res
, vol.71
, pp. 76-84
-
-
Cullis, E.R.1
Kalber, T.L.2
Ashton, S.E.3
-
12
-
-
0142155561
-
Vascular targeting effects of ZD6126 in a C3H mouse mammary carcinoma and the enhancement of radiation response
-
Horsman M.R., and Murata R. Vascular targeting effects of ZD6126 in a C3H mouse mammary carcinoma and the enhancement of radiation response. Int J Radiat Oncol Biol Phys 57 (2003) 1047-1055
-
(2003)
Int J Radiat Oncol Biol Phys
, vol.57
, pp. 1047-1055
-
-
Horsman, M.R.1
Murata, R.2
-
13
-
-
0037778194
-
Tumour dose response to the antivascular agent ZD6126 assessed by magnetic resonance imaging
-
Robinson S.P., McIntyre D.J.O., Checkley D., et al. Tumour dose response to the antivascular agent ZD6126 assessed by magnetic resonance imaging. Br J Cancer 88 (2003) 1592-1597
-
(2003)
Br J Cancer
, vol.88
, pp. 1592-1597
-
-
Robinson, S.P.1
McIntyre, D.J.O.2
Checkley, D.3
-
14
-
-
2542523230
-
Magnetic resonance imaging measurements of the response of murine and human tumors to the vascular-targeting agent ZD6126
-
Evelhoch J.L., LoRusso P.M., He Z., et al. Magnetic resonance imaging measurements of the response of murine and human tumors to the vascular-targeting agent ZD6126. Clin Cancer Res 10 (2004) 3650-3657
-
(2004)
Clin Cancer Res
, vol.10
, pp. 3650-3657
-
-
Evelhoch, J.L.1
LoRusso, P.M.2
He, Z.3
-
15
-
-
0037382380
-
Vascular-targeting activity of ZD6126, a novel tubulin-binding agent
-
Micheletti G., Poli M., Borsotti P., et al. Vascular-targeting activity of ZD6126, a novel tubulin-binding agent. Cancer Res 63 (2003) 1534-1537
-
(2003)
Cancer Res
, vol.63
, pp. 1534-1537
-
-
Micheletti, G.1
Poli, M.2
Borsotti, P.3
-
16
-
-
0035100888
-
Biomarkers Definition Working Group. Biomarkers and surrogate endpoints: preferred definitions and conceptual framework
-
Biomarkers Definition Working Group. Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clin Pharm Ther 69 (2001) 89-95
-
(2001)
Clin Pharm Ther
, vol.69
, pp. 89-95
-
-
-
17
-
-
0038376001
-
Imaging of angiogenesis: from microscope to clinic
-
McDonald D.M., and Choyke P.L. Imaging of angiogenesis: from microscope to clinic. Nat Med 9 (2003) 713-725
-
(2003)
Nat Med
, vol.9
, pp. 713-725
-
-
McDonald, D.M.1
Choyke, P.L.2
-
20
-
-
0034047595
-
Applications of magnetic resonance in model systems: Cancer therapeutics
-
Evelhoch J.L., Gillies R.J., Karczmar G.S., et al. Applications of magnetic resonance in model systems: Cancer therapeutics. Neoplasia 2 (2000) 152-165
-
(2000)
Neoplasia
, vol.2
, pp. 152-165
-
-
Evelhoch, J.L.1
Gillies, R.J.2
Karczmar, G.S.3
-
21
-
-
19944394201
-
The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: Issues and recommendations
-
Leach M.O., Brindle K.M., Evelhoch J.L., et al. The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: Issues and recommendations. Br J Cancer 92 (2005) 1599-1610
-
(2005)
Br J Cancer
, vol.92
, pp. 1599-1610
-
-
Leach, M.O.1
Brindle, K.M.2
Evelhoch, J.L.3
-
22
-
-
0025257041
-
Ultrasmall superparamagnetic iron oxide: Characterization of a new class of contrast agents for MR imaging
-
Weissleder R., Elizondo G., Wittenberg J., et al. Ultrasmall superparamagnetic iron oxide: Characterization of a new class of contrast agents for MR imaging. Radiology 175 (1990) 489-493
-
(1990)
Radiology
, vol.175
, pp. 489-493
-
-
Weissleder, R.1
Elizondo, G.2
Wittenberg, J.3
-
23
-
-
9244232783
-
Applications of ultrasmall superparamagnetic iron oxide contrast agents in the MR study of animal models
-
Wu E.X., Tang H., and Jensen J.H. Applications of ultrasmall superparamagnetic iron oxide contrast agents in the MR study of animal models. NMR Biomed 17 (2004) 478-483
-
(2004)
NMR Biomed
, vol.17
, pp. 478-483
-
-
Wu, E.X.1
Tang, H.2
Jensen, J.H.3
-
24
-
-
12244264783
-
Tumor vascular architecture and function evaluated by non-invasive susceptibility MRI methods and immunohistochemistry
-
Robinson S.P., Rijken P.F., Howe F.A., et al. Tumor vascular architecture and function evaluated by non-invasive susceptibility MRI methods and immunohistochemistry. J Magn Reson Imaging 17 (2003) 445-454
-
(2003)
J Magn Reson Imaging
, vol.17
, pp. 445-454
-
-
Robinson, S.P.1
Rijken, P.F.2
Howe, F.A.3
-
26
-
-
0042941443
-
Effects of overexpression of dimethylarginine dimethylaminohydrolase on tumor angiogenesis assessed by susceptibility magnetic resonance imaging
-
Kostourou V., Robinson S.P., Whitley G.S., et al. Effects of overexpression of dimethylarginine dimethylaminohydrolase on tumor angiogenesis assessed by susceptibility magnetic resonance imaging. Cancer Res 63 (2003) 4960-4966
-
(2003)
Cancer Res
, vol.63
, pp. 4960-4966
-
-
Kostourou, V.1
Robinson, S.P.2
Whitley, G.S.3
-
27
-
-
27744607653
-
Patupilone induced vascular disruption in orthotopic rodent tumor models detected by magnetic resonance imaging and interstitial fluid pressure
-
Ferretti S., Allegrini P.R., O'Reilly T., et al. Patupilone induced vascular disruption in orthotopic rodent tumor models detected by magnetic resonance imaging and interstitial fluid pressure. Clin Cancer Res 11 (2005) 7773-7784
-
(2005)
Clin Cancer Res
, vol.11
, pp. 7773-7784
-
-
Ferretti, S.1
Allegrini, P.R.2
O'Reilly, T.3
-
28
-
-
20344377609
-
Acute tumor response to ZD6126 assessed by intrinsic susceptibility magnetic resonance imaging
-
Robinson S.P., Kalber T.L., Howe F.A., et al. Acute tumor response to ZD6126 assessed by intrinsic susceptibility magnetic resonance imaging. Neoplasia (2005) 466-474
-
(2005)
Neoplasia
, pp. 466-474
-
-
Robinson, S.P.1
Kalber, T.L.2
Howe, F.A.3
-
29
-
-
16744368637
-
United Kingdom Co-Ordinating Committee on Cancer Research (UKCCCR) guidelines for the welfare of animals in experimental neoplasia
-
Workman P., Twentyman P., Balkwill F., et al. United Kingdom Co-Ordinating Committee on Cancer Research (UKCCCR) guidelines for the welfare of animals in experimental neoplasia. Br J Cancer 77 (1998) 1-10
-
(1998)
Br J Cancer
, vol.77
, pp. 1-10
-
-
Workman, P.1
Twentyman, P.2
Balkwill, F.3
-
30
-
-
0019431468
-
Effect of bromocriptine on DNA synthesis, growth and hormone secretion of spontaneous pituitary tumours in the rat
-
Prysor-Jones R.A., and Jenkins J.S. Effect of bromocriptine on DNA synthesis, growth and hormone secretion of spontaneous pituitary tumours in the rat. J Endocrinol 88 (1981) 463-469
-
(1981)
J Endocrinol
, vol.88
, pp. 463-469
-
-
Prysor-Jones, R.A.1
Jenkins, J.S.2
-
31
-
-
33646342514
-
Rat tumor response to the vascular-disrupting agent 5,6-dimethylxanthenone-4-acetic acid as measured by dynamic contrast-enhanced magnetic resonance imaging, plasma 5-hydroxyindoleacetic acid levels, and tumor necrosis
-
McPhail L.D., McIntyre D.J.O., Ludwig C., et al. Rat tumor response to the vascular-disrupting agent 5,6-dimethylxanthenone-4-acetic acid as measured by dynamic contrast-enhanced magnetic resonance imaging, plasma 5-hydroxyindoleacetic acid levels, and tumor necrosis. Neoplasia 8 (2006) 199-206
-
(2006)
Neoplasia
, vol.8
, pp. 199-206
-
-
McPhail, L.D.1
McIntyre, D.J.O.2
Ludwig, C.3
-
32
-
-
0023952081
-
Effect of injectable or inhalational anesthetics and of neuroleptic, neuroleptanalgesic, and sedative agents on tumor blood flow
-
Menke H., and Vaupel P. Effect of injectable or inhalational anesthetics and of neuroleptic, neuroleptanalgesic, and sedative agents on tumor blood flow. Radiat Res 114 (1988) 64-76
-
(1988)
Radiat Res
, vol.114
, pp. 64-76
-
-
Menke, H.1
Vaupel, P.2
-
33
-
-
0033625382
-
NC100150 injection, a preparation of optimized iron oxide nanoparticles for positive-contrast MR angiography
-
Kellar K.E., Fujii D.K., Gunther W.H.H., et al. NC100150 injection, a preparation of optimized iron oxide nanoparticles for positive-contrast MR angiography. J Magn Reson Imaging 11 (2000) 488-494
-
(2000)
J Magn Reson Imaging
, vol.11
, pp. 488-494
-
-
Kellar, K.E.1
Fujii, D.K.2
Gunther, W.H.H.3
-
34
-
-
0022258449
-
Cell selection from a murine tumour using the fluorescent probe Hoechst 33342
-
Chaplin D.J., Durand R.E., and Olive P.L. Cell selection from a murine tumour using the fluorescent probe Hoechst 33342. Br J Cancer 51 (1985) 569-572
-
(1985)
Br J Cancer
, vol.51
, pp. 569-572
-
-
Chaplin, D.J.1
Durand, R.E.2
Olive, P.L.3
-
35
-
-
0032718994
-
Flow and oxygenation dependent (FLOOD) contrast MR imaging to monitor the response of rat tumors to carbogen breathing
-
Howe F.A., Robinson S.P., Rodrigues L.M., et al. Flow and oxygenation dependent (FLOOD) contrast MR imaging to monitor the response of rat tumors to carbogen breathing. Magn Reson Imaging 17 (1999) 1307-1318
-
(1999)
Magn Reson Imaging
, vol.17
, pp. 1307-1318
-
-
Howe, F.A.1
Robinson, S.P.2
Rodrigues, L.M.3
-
37
-
-
0037106501
-
Effects of 5,6-dimethylxanthenone-4-acetic acid on human tumor microcirculation assessed by dynamic contrast-enhanced magnetic resonance imaging
-
Galbraith S.M., Rustin G.J.S., Lodge M.A., et al. Effects of 5,6-dimethylxanthenone-4-acetic acid on human tumor microcirculation assessed by dynamic contrast-enhanced magnetic resonance imaging. J Clin Oncol 20 (2002) 3826-3840
-
(2002)
J Clin Oncol
, vol.20
, pp. 3826-3840
-
-
Galbraith, S.M.1
Rustin, G.J.S.2
Lodge, M.A.3
-
38
-
-
0036197311
-
Evaluation of the anti-vascular effects of combretastatin in rodent tumours by dynamic contrast enhanced MRI
-
Maxwell R.J., Wilson J., Prise V.E., et al. Evaluation of the anti-vascular effects of combretastatin in rodent tumours by dynamic contrast enhanced MRI. NMR Biomed 15 (2002) 89-98
-
(2002)
NMR Biomed
, vol.15
, pp. 89-98
-
-
Maxwell, R.J.1
Wilson, J.2
Prise, V.E.3
-
39
-
-
0042386691
-
Combretastatin A4 phosphate has tumor antivascular activity in rat and man as demonstrated by dynamic magnetic resonance imaging
-
Galbraith S.M., Maxwell R.J., Lodge M.A., et al. Combretastatin A4 phosphate has tumor antivascular activity in rat and man as demonstrated by dynamic magnetic resonance imaging. J Clin Oncol 21 (2003) 2831-2842
-
(2003)
J Clin Oncol
, vol.21
, pp. 2831-2842
-
-
Galbraith, S.M.1
Maxwell, R.J.2
Lodge, M.A.3
-
40
-
-
0037096814
-
A phase I pharmacokinetic and translational study of the novel vascular targeting agent combretastatin A-4 phosphate on a single-dose intravenous schedule in patients with advanced cancer
-
Dowlati A., Robertson K., Cooney M., et al. A phase I pharmacokinetic and translational study of the novel vascular targeting agent combretastatin A-4 phosphate on a single-dose intravenous schedule in patients with advanced cancer. Cancer Res 62 (2002) 3408-3416
-
(2002)
Cancer Res
, vol.62
, pp. 3408-3416
-
-
Dowlati, A.1
Robertson, K.2
Cooney, M.3
-
41
-
-
27144541488
-
Effect of vascular targeting agent in rat tumor model: dynamic contrast-enhanced versus diffusion-weighted MR imaging
-
Thoeny H.C., De Keyzer F., Vandecaveye V., et al. Effect of vascular targeting agent in rat tumor model: dynamic contrast-enhanced versus diffusion-weighted MR imaging. Radiology 237 (2005) 492-499
-
(2005)
Radiology
, vol.237
, pp. 492-499
-
-
Thoeny, H.C.1
De Keyzer, F.2
Vandecaveye, V.3
-
43
-
-
18844385964
-
Tumor dose response to the vascular disrupting agent, 5,6-dimethylxanthenone-4-acetic acid, using in vivo magnetic resonance spectroscopy
-
McPhail L.D., Chung Y.L., Madhu B., et al. Tumor dose response to the vascular disrupting agent, 5,6-dimethylxanthenone-4-acetic acid, using in vivo magnetic resonance spectroscopy. Clin Cancer Res 11 (2005) 3705-3713
-
(2005)
Clin Cancer Res
, vol.11
, pp. 3705-3713
-
-
McPhail, L.D.1
Chung, Y.L.2
Madhu, B.3
-
44
-
-
33646417630
-
The effects of the vascular disrupting agents combretastatin A-4 disodium phosphate, 5,6-dimethylxanthenone-4-acetic acid and ZD6126 in a murine tumour: A comparative assessment using MRI and MRS
-
Breidahl T., Nielsen F., Stodkilde-Jorgensen H., et al. The effects of the vascular disrupting agents combretastatin A-4 disodium phosphate, 5,6-dimethylxanthenone-4-acetic acid and ZD6126 in a murine tumour: A comparative assessment using MRI and MRS. Acta Oncol 45 (2006) 306-316
-
(2006)
Acta Oncol
, vol.45
, pp. 306-316
-
-
Breidahl, T.1
Nielsen, F.2
Stodkilde-Jorgensen, H.3
-
45
-
-
0034986033
-
Pre-clinical results with Clariscan (NC100150 injection); experience from different disease models
-
Bjornerud A., Johansson L.O., and Ahlstrom H.K. Pre-clinical results with Clariscan (NC100150 injection); experience from different disease models. MAGMA 12 (2001) 99-103
-
(2001)
MAGMA
, vol.12
, pp. 99-103
-
-
Bjornerud, A.1
Johansson, L.O.2
Ahlstrom, H.K.3
-
46
-
-
14844330711
-
Intravascular contrast agent-enhanced MRI measuring contrast clearance and tumor blood volume and the effects of vascular modifiers in an experimental tumor
-
Bentzen L., Vestergaard-Poulsen P., Nielsen T., et al. Intravascular contrast agent-enhanced MRI measuring contrast clearance and tumor blood volume and the effects of vascular modifiers in an experimental tumor. Int J Radiat Oncol Biol Phys 61 (2005) 1208-1215
-
(2005)
Int J Radiat Oncol Biol Phys
, vol.61
, pp. 1208-1215
-
-
Bentzen, L.1
Vestergaard-Poulsen, P.2
Nielsen, T.3
-
47
-
-
0035143782
-
MR imaging characterization of microvessels in experimental breast tumors by using a particulate contrast agent with histopathologic correlation
-
Turetschek K., Huber S., Floyd E., et al. MR imaging characterization of microvessels in experimental breast tumors by using a particulate contrast agent with histopathologic correlation. Radiology 218 (2001) 562-569
-
(2001)
Radiology
, vol.218
, pp. 562-569
-
-
Turetschek, K.1
Huber, S.2
Floyd, E.3
-
48
-
-
0037612351
-
New intravascular contrast agent applied to dynamic contrast enhanced MR imaging of human breast cancer
-
Rydland J., Bjornerud A., Haugen O., et al. New intravascular contrast agent applied to dynamic contrast enhanced MR imaging of human breast cancer. Acta Radiol 44 (2003) 275-283
-
(2003)
Acta Radiol
, vol.44
, pp. 275-283
-
-
Rydland, J.1
Bjornerud, A.2
Haugen, O.3
-
49
-
-
0031756068
-
NMR imaging of changes in vascular morphology due to tumor angiogenesis
-
Dennie J., Mandeville J.B., Boxerman J.L., et al. NMR imaging of changes in vascular morphology due to tumor angiogenesis. Magn Reson Med 40 (1998) 793-799
-
(1998)
Magn Reson Med
, vol.40
, pp. 793-799
-
-
Dennie, J.1
Mandeville, J.B.2
Boxerman, J.L.3
-
50
-
-
0035001620
-
Differentiation of nonmetastatic and metastatic rodent prostate tumors with high spectral and spatial resolution MRI
-
Fan X., River J.N., Zamora M., et al. Differentiation of nonmetastatic and metastatic rodent prostate tumors with high spectral and spatial resolution MRI. Magn Reson Med 45 (2001) 1046-1055
-
(2001)
Magn Reson Med
, vol.45
, pp. 1046-1055
-
-
Fan, X.1
River, J.N.2
Zamora, M.3
-
51
-
-
0036569804
-
Enhancement of radiation therapy by the novel vascular targeting agent ZD6126
-
Siemann D.W., and Rojiani A.M. Enhancement of radiation therapy by the novel vascular targeting agent ZD6126. Int J Radiat Oncol Biol Phys 53 (2002) 164-171
-
(2002)
Int J Radiat Oncol Biol Phys
, vol.53
, pp. 164-171
-
-
Siemann, D.W.1
Rojiani, A.M.2
|