No association between the -3081A/T polymorphism in the norepinephrine transporter gene promoter and personality traits in healthy subjects

Neuroscience Letters

Volumn 425, Issue 3, 2007, Pages 192-194

  Suzuki, Akihito ^a   Matsumoto, Yoshihiko ^a   Ishii, Genki ^a   Oshino, Shingo ^a   Goto, Kaoru ^a   Otani, Koichi ^a  

^a YAMAGATA UNIVERSITY   (Japan)

Author keywords

Norepinephrine transporter; Personality; Polymorphism; Temperament and Character Inventory (TCI)

Indexed keywords

NORADRENALIN TRANSPORTER;

ADULT; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENETIC ASSOCIATION; GENETIC TRAIT; GENOTYPE; HUMAN; HUMAN EXPERIMENT; MALE; MULTIVARIATE ANALYSIS OF VARIANCE; NEUROTRANSMISSION; NORMAL HUMAN; PERSONALITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; TEMPERAMENT;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; BRAIN; BRAIN CHEMISTRY; DNA MUTATIONAL ANALYSIS; FEMALE; GENETIC MARKERS; GENETIC SCREENING; GENOTYPE; HUMANS; JAPAN; MALE; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; PERSONALITY; PERSONALITY TESTS; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); REFERENCE VALUES; SEX FACTORS; TEMPERAMENT;

EID: 34548687227     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2007.08.024     Document Type: Article

References (14)

1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. fourth ed. (1994), American Psychiatric Association, Washington, DC
2. Bruss M., Kunz J., Lingen B., and Bonisch H. Chromosomal mapping of the human gene for the tricyclic antidepressant-sensitive noradrenaline transporter. Hum. Genet. 91 (1993) 278-280
3. Cloninger C.R., Przybeck T.R., Svrakic D.M., and Wetzel R.D. The Temperament and Character Inventory (TCI): A Guide to Its Development and Use (1994), Center for Psychobiology of Personality, Washington University, St. Louis, Missouri
4. Garland E.M., Hahn M.K., Ketch T.P., Keller N.R., Kim C.H., Kim K.S., Biaggioni I., Shannon J.R., Blakely R.D., and Robertson D. Genetic basis of clinical catecholamine disorders. Ann. N.Y. Acad. Sci. 971 (2002) 506-514
5. Hall F.S., Li X.F., Sora I., Xu F., Caron M., Lesch K.P., Murphy D.L., and Uhl G.R. Cocaine mechanisms: enhanced cocaine, fluoxetine and nisoxetine place preferences following monoamine transporter deletions. Neuroscience 115 (2002) 153-161
6. Ham B.J., Choi M.J., Lee H.J., Kang R.H., and Lee M.S. Reward dependence is related to norepinephrine transporter T-182C gene polymorphism in a Korean population. Psychiat. Genet. 15 (2005) 145-147
7. Kijima N., Saito R., Suzuki M., Yoshino A., Ono Y., Kato M., and Kitamura T. Cloninger's seven factor model of temperament and character and Japanese version of Temperament and Character Inventory (TCI). Jpn. J. Psychiatr. Diagn. 7 (1996) 379-399 (Japanese)
8. Kim C.H., Hahn M.K., Joung Y., Anderson S.L., Steele A.H., MazeiRobinson M.S., Gizer I., Teicher M.H., Cohen B.M., Robertson D., Waldman I.D., Blakely R.D., and Kim K.S. A polymorphism in the norepinephrine transporter gene alters promoter activity and is associated with attention-deficit hyperactivity disorder. P.N.A.S. 103 (2006) 19164-19169
9. Lee H.J., Lee H.S., Kim Y.K., Lee M.S., Jung I.K., Suh K.Y., and Kim S. D2 and D4 dopamine receptor gene polymorphisms and personality traits in a young Korean population. Am. J. Med. Genet. B 121 (2003) 44-49
10. Mitsuyasu H., Hirata N., Sakai Y., Shibata H., Takeda Y., Ninomiya H., Kawasaki H., Tashiro N., and Fukumaki Y. Association analysis of polymorphisms in the upstream region of the human dopamine D4 receptor gene (DRD4) with schizophrenia and personality traits. J. Hum. Genet. 46 (2001) 26-31
11. Samochowiec J., Rybakowski F., Czerski P., Zarzena M., Stepien G., Pelka-Wysiecka J., Horodnicki J., Rybakowski J.K., and Hauser J. Polymorphism in the dopamine, serotonin and norepinephrine transporter genes and their relationship to temperamental dimensions measured by the Temperament and Character Inventory in healthy volunteers. Neuropsychobiology 43 (2001) 248-253
12. Tsai S.J., Wang Y.H., and Hong C.J. Norepinephrine transporter and α2c adrenoceptor allelic variants and personality factors. Am. J. Med. Genet. 114 (2002) 649-651
13. Wang Y.M., Xu F., Gainetdinov R.R., and Caron M.G. Genetic approaches to studying norepinephrine function: knockout of the mouse norepinephrine transporter gene. Biol. Psychiatry 46 (1999) 1124-1130
14. Xu F., Gainetdinov R.R., Wetsel W.C., Jones S.R., Bohn L.M., Miller G.W., Wang Y.M., and Caron M.G. Mice lacking the norepinephrine transporter are supersensitive to psychostimulants. Nat. Neurosci. 3 (2000) 465-471