Incidence, prevalence and clinical course of primary biliary cirrhosis in a Spanish community

European Journal of Gastroenterology and Hepatology

Volumn 19, Issue 10, 2007, Pages 859-864

  Pla, Xavier ^a   Vergara, Mercedes ^b,e   Gil, Montserrat ^b   Dalmau, Blai ^b   Cisteró, Berta ^a   Bella, Rosa M ^c   Real, Jordi ^d  

^a Internal Medicine Service

^b Digestive Disease Service

^c Pathology Service

^d Biostatistics and Clinical Epidemiology Service   (United States)

^e Servei de Digestiu   (Spain)

Author keywords

Autoimmune cholangiopathy; Clinical course; Epidemiology; Incidence; Prevalence; Primary biliary cirrhosis; Ursodeoxycolic acid

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; GAMMA GLUTAMYLTRANSFERASE; MITOCHONDRION ANTIBODY; URSODEOXYCHOLIC ACID;

ADULT; AGED; ARTICLE; CHOLESTASIS; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; ENDOSCOPY; FEMALE; FOLLOW UP; HUMAN; INCIDENCE; LIVER BIOPSY; LIVER FUNCTION TEST; LIVER HISTOLOGY; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD; OUTCOME ASSESSMENT; PREVALENCE; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL; PROTHROMBIN TIME; SPAIN; SYMPTOM; TREATMENT DURATION;

ADULT; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; CHOLAGOGUES AND CHOLERETICS; EPIDEMIOLOGIC METHODS; FEMALE; HUMANS; LIVER CIRRHOSIS, BILIARY; MALE; MIDDLE AGED; SEVERITY OF ILLNESS INDEX; SPAIN; TREATMENT OUTCOME; URSODEOXYCHOLIC ACID;

EID: 34548666741     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/MEG.0b013e328277594a     Document Type: Article

References (32)

1. Kaplan MM, Gershwin ME. Primary biliary cirrhosis. N Engl J Med 2005; 353:1261-1273.
2. Vierling JM. Primary biliary cirrhosis and autoimmune cholangiopathy. Clin Liver Dis 2004; 8:177-194.
3. Selmi C, Invernizzi P, Keeffe EB, Coppel RL, Podda M, Rossaro L, et al. Epidemiology and pathogenesis of primary biliary cirrhosis. J Clin Gastroenterol 2004; 38:264-271.
4. Caballero Plasencia AM, Lopez CC, Valenzuela BM, Montero GM, Muros Navarro MC, de los Reyes Garcia MC, et al. [Epidemiology of primary biliary cirrhosis in the South area of Granada]. Med Clin (Barc) 1991; 96:481-485.
5. James OF, Bhopal R, Howel D, Gray J, Burt AD, Metcalf JV. Primary biliary cirrhosis once rare, now common in the United Kingdom? Hepatology 1999; 30:390-394.
6. Kim WR, Lindor KD, Locke GR III, Therneau TM, Homburger HA, Batts KP, et al. Epidemiology and natural history of primary biliary cirrhosis in a US community. Gastroenterology 2000; 119:1631-1636.
7. Springer J, Cauch-Dudek K, O'Rourke K, Wanless IR, Heathcote EJ. Asymptomatic primary biliary cirrhosis: a study of its natural history and prognosis. Am J Gastroenterol 1999; 94:47-53.
8. Heathcote EJ. Management of primary biliary cirrhosis. The American Association for the Study of Liver Diseases practice guidelines. Hepatology 2000; 31:1005-1013.
9. Ludwig J, Dickson ER, McDonald GS. Staging of chronic nonsuppurative destructive cholangitis (syndrome of primary biliary cirrhosis). Virchows Arch A Pathol Anat Histol 1978; 379:103-112.
10. Prince MI, Chetwynd A, Craig WL, Metcalf JV, James OF. Asymptomatic primary biliary cirrhosis: clinical features, prognosis, and symptom progression in a large population based cohort. Gut 2004; 53:865-870.
11. Colombato LA, Alvarez F, Cote J, Huet PM. Autoimmune cholangiopathy: the result of consecutive primary biliary cirrhosis and autoimmune hepatitis? Gastroenterology 1994; 107:1839-1843.
12. Salo J, Caballeria L, Bruguera M, Pares A, Rodes J. [Autoimmune cholangitis or primary biliary cirrhosis without antimitochondrial antibodies?]. Gastroenterol Hepatol 1997; 20:5-10.
13. Talwalkar JA, Lindor KD. Primary biliary cirrhosis. Lancet 2003; 362:53-61.
14. Valera MJ, Smok SG, Poniachik TJ, Oksenberg RD, Silva PG, Ferrario BM, et al. [Primary biliary cirrhosis: a thirteen years experience]. Rev Med Chil 2006; 134:469-474.
15. Gershwin ME, Selmi C, Worman HJ, Gold EB, Watnik M, Utts J, et al. Risk factors and comorbidities in primary biliary cirrhosis: a controlled interview-based study of 1032 patients. Hepatology 2005; 42:1194-1202.
16. Mitchison HC, Lucey MR, Kelly PJ, Neuberger JM, Williams R, James OF. Symptom development and prognosis in primary biliary cirrhosis: a study in two centers. Gastroenterology 1990; 99:778-784.
17. Nyberg A, Loof L. Primary biliary cirrhosis: clinical features and outcome, with special reference to asymptomatic disease. Scand J Gastroenterol 1989; 24:57-64.
18. Dickson ER, Grambsch PM, Fleming TR, Fisher LD, Langworthy A. Prognosis in primary biliary cirrhosis: model for decision making. Hepatology 1989; 10:1-7.
19. Klion FM, Fabry TL, Palmer M, Schaffner F. Prediction of survival of patients with primary biliary cirrhosis. Examination of the Mayo Clinic model on a group of patients with known endpoint. Gastroenterology 1992; 102:310-313.
20. Lee YM, Kaplan MM. The natural history of PBC: has it changed? Semin Liver Dis 2005; 25:321-326.
21. Locke GR III, Therneau TM, Ludwig J, Dickson ER, Lindor KD. Time course of histological progression in primary biliary cirrhosis. Hepatology 1996; 23:52-56.
22. Chan CW, Gunsar F, Feudjo M, Rigamonti C, Vlachogiannakos J, Carpenter JR, et al. Long-term ursodeoxycholic acid therapy for primary biliary cirrhosis: a follow-up to 12 years. Aliment Pharmacol Ther 2005; 21:217-226.
23. Gluud C, Christensen E. Ursodeoxycholic acid for primary biliary cirrhosis. Cochrane Database Syst Rev 2002; 1:CD000551.
24. Poupon RE, Lindor KD, Pares A, Chazouilleres O, Poupon R, Heathcote EJ. Combined analysis of the effect of treatment with ursodeoxycholic acid on histologic progression in primary biliary cirrhosis. J Hepatol 2003; 39:12-16.
25. Pares A, Caballeria L, Rodes J. Excellent long-term survival in patients with primary biliary cirrhosis and biochemical response to ursodeoxycholic Acid. Gastroenterology 2006; 130:715-720.
26. Jones EA. Rationale for trials of long-term mycophenolate mofetil therapy for primary biliary cirrhosis. Hepatology 2002; 35:258-262.
27. Gores GJ, Wiesner RH, Dickson ER, Zinsmeister AR, Jorgensen RA, Langworthy A. Prospective evaluation of esophageal varices in primary biliary cirrhosis: development, natural history, and influence on survival. Gastroenterology 1989; 96:1552-1559.
28. Moreno SD, Cassinello OC, Gonzalez BP, Pulido OF, Castellano TG. [Epidemiology of primary biliary cirrhosis in southern Madrid]. Med Clin (Barc) 1990; 94:564-569.
29. Pares A, Bruguera M, Rodes J, Villagrasa M, Guardia J, Seres I, et al. [Epidemiology of primary biliary cirrhosis in Cataluna]. Med Clin (Barc) 1984; 82:237-241.
30. Rodrigo SL, Valerdiz Casasola CS, Rodriguez GM, Riera V Jr, Perez AR, Linares RA. [Epidemiology of primary biliary cirrhosis in Asturias]. Med Clin (Barc) 1987; 88:486-489.
31. Feld JJ, Heathcote EJ. Epidemiology of autoimmune liver disease. J Gastroenterol Hepatol 2003; 18:1118-1128.
32. Kurtovic J, Riordan SM, Williams R. The natural history of asymptomatic primary biliary cirrhosis. Monthly J Assoc Physicians 2005; 98:331-336.