NAP protects hippocampal neurons against multiple toxins

Peptides

Volumn 28, Issue 10, 2007, Pages 2004-2008

  Zemlyak, Ilona ^a,b   Manley, Nathan ^b   Sapolsky, Robert ^b   Gozes, lllana ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b STANFORD UNIVERSITY   (United States)

Author keywords

Kainic acid; NAP; Neuronal death; Oxygen glucose deprivation; Sodium cyanide

Indexed keywords

CYANIDE; GLUCOSE; KAINIC ACID; MICROTUBULE ASSOCIATED PROTEIN 2; NEUROTROPHIC FACTOR; OXYGEN; PROTEIN NAP; TOXIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; EXCITOTOXICITY; FETUS; HIPPOCAMPUS; HYPOXIA; IMMUNOREACTIVITY; ISCHEMIA; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; TISSUE CULTURE;

AMINO ACID SEQUENCE; ANIMALS; CELLS, CULTURED; HIPPOCAMPUS; KAINIC ACID; NEURONS; OLIGOPEPTIDES; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 34548665270     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2007.08.004     Document Type: Article

References (28)

1. Alcalay R.N., Giladi E., Pick C.G., and Gozes I. Intranasal administration of NAP, a neuroprotective peptide, decreases anxiety-like behavior in aging mice in the elevated plus maze. Neurosci Lett 361 (2004) 128-131
2. Bassan M., Zamostiano R., Davidson A., Pinhasov A., Giladi E., Perl O., et al. Complete sequence of a novel protein containing a femtomolar-activity-dependent neuroprotective peptide. J Neurochem 72 (1999) 1283-1293
3. Beni-Adani L., Gozes I., Cohen Y., Assaf Y., Steingart R.A., Brenneman D.E., et al. A peptide derived from activity-dependent neuroprotective protein (ADNP) ameliorates injury response in closed head injury in mice. J Pharmacol Exp Ther 296 (2001) 57-63
4. Benitez-King G., Ramirez-Rodriguez G., Ortiz L., and Meza I. The neuronal cytoskeleton as a potential therapeutical target in neurodegenerative diseases and schizophrenia. Curr Drug Targets CNS Neurol Disord 3 (2004) 515-533
5. Brooke S.M., Bliss T.M., Franklin L.R., and Sapolsky R.M. Quantification of neuron survival in monolayer cultures using an enzyme-linked immunosorbent assay approach, rather than by cell counting. Neurosci Lett 267 (1999) 21-24
6. Chen J., Kanai Y., Cowan N.J., and Hirokawa N. Projection domains of MAP2 and tau determine spacings between microtubules in dendrites and axons. Nature 360 (1992) 674-677
7. Divinski I., Holtser-Cochav M., Vulih-Schultzman I., Steingart R.A., and Gozes I. Peptide neuroprotection through specific interaction with brain tubulin. J Neurochem 98 (2006) 973-984
8. Divinski I., Mittelman L., and Gozes I. A femtomolar acting octapeptide interacts with tubulin and protects astrocytes against zinc intoxication. J Biol Chem 279 (2004) 28531-28538
9. Dong H., Csernansky C.A., Goico B., and Csernansky J.G. Hippocampal neurogenesis follows kainic acid-induced apoptosis in neonatal rats. J Neurosci 23 (2003) 1742-1749
10. Ferralli J., Doll T., and Matus A. Sequence analysis of MAP2 function in living cells. J Cell Sci 107 Pt 11 (1994) 3115-3125
11. Furman S., Steingart R.A., Mandel S., Hauser J.M., Brenneman D.E., and Gozes I. Subcellular localization and secretion of activity-dependent neuroprotective protein in astrocytes. Neuron Glia Biol 1 (2004) 193-199
12. Gozes I., Alcalay R., Giladi E., Pinhasov A., Furman S., and Brenneman D.E. NAP accelerates the performance of normal rats in the water maze. J Mol Neurosci 19 (2002) 167-170
13. Gozes I., Bachar M., Bardea A., Davidson A., Rubinraut S., Fridkin M., et al. Protection against developmental retardation in apolipoprotein E-deficient mice by a fatty neuropeptide: implications for early treatment of Alzheimer's disease. J Neurobiol 33 (1997) 329-342
14. Gozes I., and Brenneman D.E. A new concept in the pharmacology of neuroprotection. J Mol Neurosci 14 (2000) 61-68
15. Gozes I., and Divinski I. The femtomolar-acting NAP interacts with microtubules: novel aspects of astrocyte protection. J Alzheimers Dis 6 (2004) S37-S41
16. Gozes I., Morimoto B.H., Tiong J., Fox A., Sutherland K., Dangoor D., et al. NAP: research and development of a peptide derived from activity-dependent neuroprotective protein (ADNP). CNS Drug Rev 11 (2005) 353-368
17. Grundman M., Jack Jr. C.R., Petersen R.C., Kim H.T., Taylor C., Datvian M., et al. Hippocampal volume is associated with memory but not nonmemory cognitive performance in patients with mild cognitive impairment. J Mol Neurosci 20 (2003) 241-248
18. Kwei S., Jiang C., and Haddad G.G. Acute anoxia-induced alterations in MAP2 immunoreactivity and neuronal morphology in rat hippocampus. Brain Res 620 (1993) 203-210
19. Lagreze W.A., Pielen A., Steingart R., Schlunck G., Hofmann H.D., Gozes I., et al. The peptides ADNF-9 and NAP increase survival and neurite outgrowth of rat retinal ganglion cells in vitro. Invest Ophthalmol Vis Sci 46 (2005) 933-938
20. Leker R.R., Teichner A., Grigoriadis N., Ovadia H., Brenneman D.E., Fridkin M., et al. NAP, a femtomolar-acting peptide, protects the brain against ischemic injury by reducing apoptotic death. Stroke 33 (2002) 1085-1092
21. Melnikova I. Therapies for Alzheimer's disease. Nat Rev Drug Discov 6 (2007) 341-342
22. Qin L., Liu Y., Qian X., Hong J.S., and Block M.L. Microglial NADPH oxidase mediates leucine enkephalin dopaminergic neuroprotection. Ann NY Acad Sci 1053 (2005) 107-120
23. Romano J., Beni-Adani L., Nissenbaum O.L., Brenneman D.E., Shohami E., and Gozes I. A single administration of the peptide NAP induces long-term protective changes against the consequences of head injury: gene Atlas array analysis. J Mol Neurosci 18 (2002) 37-45
24. Rotstein M., Bassan H., Kariv N., Speiser Z., Harel S., and Gozes I. NAP enhances neurodevelopment of newborn apolipoprotein E-deficient mice subjected to hypoxia. J Pharmacol Exp Ther 319 (2006) 332-339
25. Smith-Swintosky V.L., Gozes I., Brenneman D.E., D'Andrea M.R., and Plata-Salaman C.R. Activity-dependent neurotrophic factor-9 and NAP promote neurite outgrowth in rat hippocampal and cortical cultures. J Mol Neurosci 25 (2005) 225-238
26. Spong C.Y., Abebe D.T., Gozes I., Brenneman D.E., and Hill J.M. Prevention of fetal demise and growth restriction in a mouse model of fetal alcohol syndrome. J Pharmacol Exp Ther 297 (2001) 774-779
27. Zamostiano R., Pinhasov A., Gelber E., Steingart R.A., Seroussi E., Giladi E., et al. Cloning and characterization of the human activity-dependent neuroprotective protein. J Biol Chem 276 (2001) 708-714
28. Zemlyak I., Furman S., Brenneman D.E., and Gozes I. A novel peptide prevents death in enriched neuronal cultures. Regul Pept 96 (2000) 39-43