Relation of Coronary Artery Calcium to Flow-Mediated Dilation and C-Reactive Protein Levels in Asymptomatic Patients With Heterozygous Familial Hypercholesterolemia

American Journal of Cardiology

Volumn 100, Issue 7, 2007, Pages 1119-1123

  Ye, Zhong Xuan ^a,b,c   Cheng, Hao Ming ^a,b   Chiou, Kuan Rau ^b,d   Huang, Po Hsun ^a,b   Lin, Shing Jong ^a,b   Charng, Min Ji ^a,b  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN B; C REACTIVE PROTEIN; CALCIUM; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADULT; ARTERY CALCIFICATION; ARTICLE; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY DILATATION; CORONARY ARTERY DISEASE; FAMILIAL DISEASE; FAMILIAL HYPERCHOLESTEROLEMIA; FEMALE; HUMAN; HYPERCHOLESTEROLEMIA; INFLAMMATION; MALE; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; RISK ASSESSMENT; SCORING SYSTEM;

ADULT; BLOOD FLOW VELOCITY; C-REACTIVE PROTEIN; CALCINOSIS; CALCIUM; CASE-CONTROL STUDIES; CORONARY ARTERIOSCLEROSIS; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; HYPERLIPOPROTEINEMIA TYPE II; MALE; TOMOGRAPHY, X-RAY COMPUTED;

EID: 34548660011     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjcard.2007.05.034     Document Type: Article

References (17)

1. Austin M.A., Hutter C.M., Zimmern R.L., and Humphries S.E. Genetic causes of monogenic heterozygous familial hypercholesterolemia: a HuGE prevalence review. Am J Epidemiol 160 (2004) 407-420
2. Taylor A.J., Feuerstein I.M., Wong H., Barko W., Brazaitis M., and O'Malley P.G. Do conventional risk factors predict subclinical coronary artery disease?. Results from the Prospective Army Coronary Calcium Project. Am Heart J 141 (2001) 463-468
3. Hoffmann U., Bodlaj G., Derfler K., Bernhard C., Wicke L., Herold C.J., and Kostner K. Quantification of coronary artery calcification in patients with FH using EBCT. Eur J Clin Invest 31 (2001) 471-475
4. Huang P.H., Chen L.C., Leu H.B., Ding P.Y., Chen J.W., Wu T.C., and Lin S.J. Enhanced coronary calcification determined by electron beam CT is strongly related to endothelial dysfunction in patients with suspected coronary artery disease. Chest 128 (2005) 810-815
5. Arad Y., Goodman K.J., Roth M., Newstein D., and Guerci A.D. Coronary calcification, coronary disease risk factors, C-reactive protein, and atherosclerotic cardiovascular disease events: the St. Francis Heart Study. J Am Coll Cardiol 46 (2005) 158-165
6. Charng M.J., Chiou K.R., Chang H.M., Cheng H.M., Ye Z.X., and Lin S.J. Identification and characterization of novel low-density lipoprotein receptor mutations of familial hypercholesterolaemia patients in Taiwan. Eur J Clin Invest 36 (2006) 866-874
7. Friedewald W.T., Levy R.I., and Fredrickson D.S. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18 (1972) 499-502
8. Cheng H.M., Ye Z.X., Chiou K.R., Lin S.J., and Charng M.J. Vascular stiffness in familial hypercholesterolaemia is associated with C-reactive protein and cholesterol burden. Eur J Clin Invest 37 (2007) 197-206
9. Agatston A.S., Janowitz W.R., Hildner F.J., Zusmer N.R., Viamonte M.J., and Detrano R. Quantification of coronary artery calcium using ultrafast computed tomography. J Am Coll Cardiol 15 (1990) 827-832
10. Mahoney L.T., Burns T.L., Stanford W., Thompson B.H., Witt J.D., Rost C.A., and Lauer R.M. Coronary risk factors measured in childhood and young adult life are associated with coronary artery calcification in young adults: the Muscatine Study. J Am Coll Cardiol 27 (1996) 277-284
11. Bowden D.W., Lange L.A., Langefeld C.D., Brosnihan K.B., Freedman B.I., Carr J.J., Wagenknecht L.E., and Herrington D.M. The relationship between C-reactive protein and subclinical cardiovascular disease in the Diabetes Heart Study (DHS). Am Heart J 150 (2005) 1032-1038
12. Meng Q., Lima J.A., Lai H., Vlahov D., Celentano D.D., Margolick J.B., and Lai S. Elevated C-reactive protein levels are associated with endothelial dysfunction in chronic cocaine users. Int J Cardiol 88 (2003) 191-198
13. Hunt M.E., O'Malley P.G., Vernalis M.N., Feuerstein I.M., and Taylor A.J. C-reactive protein is not associated with the presence or extent of calcified subclinical atherosclerosis. Am Heart J 141 (2001) 206-210
14. Hovingh G.K., Brownlie A., Bisoendial R.J., Dube M.P., Levels J.H., Petersen W., Dullaart R.P., Stroes E.S., Zwinderman A.H., de Groot E., et al. A novel apoA-I mutation (L178P) leads to endothelial dysfunction, increased arterial wall thickness, and premature coronary artery disease. J Am Coll Cardiol 44 (2004) 1429-1435
15. Brown S.L., Raal F.J., Panz V.R., Stevens B.A., and Veller M.G. High-dose atorvastatin therapy is required for significant improvement of endothelial function in heterozygous familial hypercholesterolaemic patients. Cardiovasc J S Afr 15 (2004) 70-75
16. Zouridakis E., Avanzas P., Arroyo-Espliguero R., Fredericks S., and Kaski J.C. Markers of inflammation and rapid coronary artery disease progression in patients with stable angina pectoris. Circulation 110 (2004) 1747-1753
17. Sangiorgi G., Rumberger J.A., Severson A., Edwards W.D., Gregoire J., Fitzpatrick L.A., and Schwartz R.S. Arterial calcification and not lumen stenosis is highly correlated with atherosclerotic plaque burden in humans: a histologic study of 723 coronary artery segments using nondecalcifying methodology. J Am Coll Cardiol 31 (1998) 126-133