Changes of podocyte ultrastructure and expression of podocyte-associated molecules in rats with diabetic nephropathy

Journal of Central South University (Medical Sciences)

Volumn 32, Issue 4, 2007, Pages 620-625

  Chen, Li Ping ^a   Zhou, Qiao Ling ^a   Peng, Wei Sheng ^a   Wu, Xiao Ying ^b  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b Central South University   (China)

Author keywords

Diabetic nephropathy; Podocytes; Proteinuria

Indexed keywords

MEMBRANE PROTEIN; NEPHRIN; PODOCIN; SIGNAL PEPTIDE;

ANIMAL; ARTICLE; DIABETIC NEPHROPATHY; MALE; METABOLISM; PATHOLOGY; PODOCYTE; PROTEINURIA; RAT; ULTRASTRUCTURE; WISTAR RAT;

ANIMALS; DIABETIC NEPHROPATHIES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MEMBRANE PROTEINS; PODOCYTES; PROTEINURIA; RATS; RATS, WISTAR;

EID: 34548649694     PISSN: 16727347     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Iglesias-de la Cruz M C, Ziyadeh F N, Isono M, et al. Effects of high glucose and TGF-beta 1 on the expression of collagen IV and vascular endothelial growth factor in mouse podocytes [J]. Kidney Int, 2002, 62 (3) : 901-913.
2. YANG Nian-sheng, Wu Qing-qing, JIANG Zong-pei, et al. Retinoic acid suppresses tubulointerstitial fibrosis of rat unilateral ureteral obstruction model [J]. Chin J Nephrol, 2004, 20(3) : 194-197.
3. YOU Li, YU Wu-hua, YE Hong-ying, et al. The protective effects of bovine colostrum truncated IGF-I on kidney of diabetic rats and the study of mechanism [J]. Chin J Nephrol, 2000, 16 (4) 251-255.
4. Barisoni L, Kopp B J. Update in podocyte biology, putting one's best foot forward [J]. Curr Opin Nephrol Hypertens, 2003, 12(3) : 251-259.
5. Miner J H, Li C. Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane [J]. Dev Biol, 2000, 217(1) : 278-289.
6. Saleem M A, O'Hare M J, Reiser J, et al. A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression [J]. J Am Soc Nephrol, 2002, 13 (2) : 630-638.
7. Kerjaschki D. Caugh flat - footed, podocyte damage and the molecular bases of focal glomerulosclerosis [J]. J Clin Invest, 2001, 108(5) : 1583-1587.
8. Koop K, Eikmans M, Baelde HJ, et al. Expression of podocyteassoociated molecules in acquired human kidney diseases [J]. J Am Soc Nephrol, 2003, 14(8) : 2063-2071.
9. Saleem M A, Ni L, Witherden I, et al. Co - localization of nephrin, podocin, and the actin cytoskeleton, evidence for a role in podocyte foot process formation [J]. Am J Pathol, 2002, 161 (6) : 1459-1466.
10. Toyoda M, Suzuki D, Umezono T, et al. Expression of human nephrin mRNA in diabetic nephropathy [J]. Nephrol Dial Transplant, 2004, 19(2) : 380-385.
11. Kathryn E, White W, Rudolf W, et al. Structural alterations to the podocyte are related to proteinuria in 2 diabetic patients [J]. Nephrol Dial Transplant, 2004, 19 (6) : 1437-1440.
12. Mohammed S, Razzaque T, Takashi T. Role of glomerular epithelial cell derived heat shock protein 47 in experimental lipid nephropathy [J]. Kidney Int, 1999, 56 (suppl) : 256-259.
13. Ding G, Reddy K, Kapasi AA, et al. Angiotensin II induces apoptosis in rat glomerular epithelial cells [J]. Am J Renal Physiol, 2002, 283(1) : F173-180.
14. Benzing T. Signaling at the slit diaphragm [J]. J Am Soc Nephrol, 2004, 15(3) : 1382-1391.