메뉴 건너뛰기




Volumn 60, Issue 12, 2007, Pages 1220-1225

"Omics" research, monetization of intellectual property and fragmentation of knowledge: can clinical epidemiology strengthen integrative research?

Author keywords

Clinical epidemiology; Genomics; Methods; Proteomics; Relevance; Validity

Indexed keywords

ARTICLE; BIOMICS; BIOTECHNOLOGICAL PROCEDURES; CLINICAL RESEARCH; COMMERCIAL PHENOMENA; COMPUTER PROGRAM; GENOMICS; HUMAN; INTERNET; KNOWLEDGE; MARKETING; MEDICAL TECHNOLOGY; METABOLOMICS; METHODOLOGY; MONEY; PATENT; PRIORITY JOURNAL; PROGNOSIS; PROTEOMICS; SEMICONDUCTOR; THINKING; VALIDATION PROCESS;

EID: 34548641313     PISSN: 08954356     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jclinepi.2007.06.010     Document Type: Note
Times cited : (20)

References (40)
  • 2
    • 0031693015 scopus 로고    scopus 로고
    • Epidemiology: bridges over (and across) roaring levels
    • Porta M., and Alvarez-Dardet C. Epidemiology: bridges over (and across) roaring levels. J Epidemiol Community Health 52 (1998) 605
    • (1998) J Epidemiol Community Health , vol.52 , pp. 605
    • Porta, M.1    Alvarez-Dardet, C.2
  • 3
    • 0001604043 scopus 로고    scopus 로고
    • Epidemiologic coherence. Re: "Biologic plausibility in causal inference: current method and practice"
    • Porta M. Epidemiologic coherence. Re: "Biologic plausibility in causal inference: current method and practice". Am J Epidemiol 150 (1999) 217-218
    • (1999) Am J Epidemiol , vol.150 , pp. 217-218
    • Porta, M.1
  • 4
    • 0034120675 scopus 로고    scopus 로고
    • How is causal inference practised by the biological sciences?
    • Porta M., and Álvarez-Dardet C. How is causal inference practised by the biological sciences?. J Epidemiol Community Health 54 (2000) 559-560
    • (2000) J Epidemiol Community Health , vol.54 , pp. 559-560
    • Porta, M.1    Álvarez-Dardet, C.2
  • 5
    • 0141514713 scopus 로고    scopus 로고
    • Semiology, proteomics and the early detection of symptomatic cancer
    • Porta M., Fernandez E., and Alguacil J. Semiology, proteomics and the early detection of symptomatic cancer. J Clin Epidemiol 56 (2003) 815-819
    • (2003) J Clin Epidemiol , vol.56 , pp. 815-819
    • Porta, M.1    Fernandez, E.2    Alguacil, J.3
  • 6
    • 13444295207 scopus 로고    scopus 로고
    • Epidemiologic methods: beyond clinical medicine, beyond epidemiology
    • Bolúmar F., and Porta M. Epidemiologic methods: beyond clinical medicine, beyond epidemiology. Eur J Epidemiol 19 (2004) 733-735
    • (2004) Eur J Epidemiol , vol.19 , pp. 733-735
    • Bolúmar, F.1    Porta, M.2
  • 7
    • 34548161329 scopus 로고    scopus 로고
    • Assessing the social meaning, value and implications of research in genomics
    • [Editorial]
    • Lumbreras B., Porta M., and Hernández-Aguado I. Assessing the social meaning, value and implications of research in genomics. [Editorial]. J Epidemiol Community Health 61 (2007) 755-756
    • (2007) J Epidemiol Community Health , vol.61 , pp. 755-756
    • Lumbreras, B.1    Porta, M.2    Hernández-Aguado, I.3
  • 11
    • 33750634123 scopus 로고    scopus 로고
    • The proteomic search for diagnostic biomarkers: lost in translation?
    • Zolg W. The proteomic search for diagnostic biomarkers: lost in translation?. Mol Cell Proteomics 5 (2006) 1720-1726
    • (2006) Mol Cell Proteomics , vol.5 , pp. 1720-1726
    • Zolg, W.1
  • 13
    • 0037312597 scopus 로고    scopus 로고
    • Exploring environmental causes of altered ras effects: fragmentation plus integration?
    • Porta M., Ayude D., Alguacil J., and Jariod M. Exploring environmental causes of altered ras effects: fragmentation plus integration?. Mol Carcinog 36 (2003) 45-52
    • (2003) Mol Carcinog , vol.36 , pp. 45-52
    • Porta, M.1    Ayude, D.2    Alguacil, J.3    Jariod, M.4
  • 14
    • 13844322072 scopus 로고    scopus 로고
    • Lessons from controversy: ovarian cancer screening and serum proteomics
    • Ransohoff D.F. Lessons from controversy: ovarian cancer screening and serum proteomics. J Natl Cancer Inst 97 (2005) 315-319
    • (2005) J Natl Cancer Inst , vol.97 , pp. 315-319
    • Ransohoff, D.F.1
  • 15
    • 1942438016 scopus 로고    scopus 로고
    • Rules of evidence for cancer molecular-marker discovery and validation
    • Ransohoff D.F. Rules of evidence for cancer molecular-marker discovery and validation. Nat Rev Cancer 4 (2004) 309-314
    • (2004) Nat Rev Cancer , vol.4 , pp. 309-314
    • Ransohoff, D.F.1
  • 16
    • 13444283596 scopus 로고    scopus 로고
    • Bias as a threat to the validity of cancer molecular-marker research
    • Ransohoff D.F. Bias as a threat to the validity of cancer molecular-marker research. Nat Rev Cancer 5 (2005) 142-149
    • (2005) Nat Rev Cancer , vol.5 , pp. 142-149
    • Ransohoff, D.F.1
  • 17
    • 5144226344 scopus 로고    scopus 로고
    • Evaluating discovery-based research: when biologic reasoning cannot work
    • Ransohoff D.F. Evaluating discovery-based research: when biologic reasoning cannot work. Gastroenterology 127 (2004) 1028
    • (2004) Gastroenterology , vol.127 , pp. 1028
    • Ransohoff, D.F.1
  • 18
    • 35848962931 scopus 로고    scopus 로고
    • How to improve reliability and efficiency of research about molecular markers: roles of phases, guidelines, and study design
    • Ransohoff D.F. How to improve reliability and efficiency of research about molecular markers: roles of phases, guidelines, and study design. J Clin Epidemiol 60 (2007) 1205-1219
    • (2007) J Clin Epidemiol , vol.60 , pp. 1205-1219
    • Ransohoff, D.F.1
  • 20
    • 35848938929 scopus 로고    scopus 로고
    • Pollack A. New cancer test stirs hope and concern. N Y Times, 3 Feb 2004, pp. 1 and 6.
  • 21
    • 35848961886 scopus 로고    scopus 로고
    • Armstrong D. Medical journal spikes article on industry ties of kidney group Wall St J. 26 Dec 2006, p. B1.
  • 22
    • 0036234192 scopus 로고    scopus 로고
    • The winding road towards evidence based diagnoses
    • Hernández-Aguado I. The winding road towards evidence based diagnoses. J Epidemiol Community Health 56 (2002) 323-325
    • (2002) J Epidemiol Community Health , vol.56 , pp. 323-325
    • Hernández-Aguado, I.1
  • 23
    • 0344327133 scopus 로고    scopus 로고
    • Clinical epidemiological quality in molecular genetic research: the need for methodological standards
    • Bogardus Jr. S.T., Concato J., and Feinstein A.R. Clinical epidemiological quality in molecular genetic research: the need for methodological standards. JAMA 281 (1999) 1919-1926
    • (1999) JAMA , vol.281 , pp. 1919-1926
    • Bogardus Jr., S.T.1    Concato, J.2    Feinstein, A.R.3
  • 24
    • 0029116527 scopus 로고
    • Use of methodological standards in diagnostic test research. Getting better but still not good
    • Reid M.C., Lachs M.S., and Feinstein A.R. Use of methodological standards in diagnostic test research. Getting better but still not good. JAMA 274 (1995) 645-651
    • (1995) JAMA , vol.274 , pp. 645-651
    • Reid, M.C.1    Lachs, M.S.2    Feinstein, A.R.3
  • 26
    • 2542574847 scopus 로고    scopus 로고
    • Research on diagnostic tests in Medicina Clinica. A methodological assessment
    • Ramos Rincón J.M., and Hernández-Aguado I. Research on diagnostic tests in Medicina Clinica. A methodological assessment. Med Clin (Barc) 111 (1998) 129-134
    • (1998) Med Clin (Barc) , vol.111 , pp. 129-134
    • Ramos Rincón, J.M.1    Hernández-Aguado, I.2
  • 27
    • 0037232979 scopus 로고    scopus 로고
    • Standards for Reporting of Diagnostic Accuracy. The STARD statement for reporting studies of diagnostic accuracy: explanation and elaboration
    • Bossuyt P.M., Reitsma J.B., Bruns D.E., Gatsonis C.A., Glasziou P.P., Irwig L.M., et al. Standards for Reporting of Diagnostic Accuracy. The STARD statement for reporting studies of diagnostic accuracy: explanation and elaboration. Clin Chem 49 (2003) 7-18
    • (2003) Clin Chem , vol.49 , pp. 7-18
    • Bossuyt, P.M.1    Reitsma, J.B.2    Bruns, D.E.3    Gatsonis, C.A.4    Glasziou, P.P.5    Irwig, L.M.6
  • 28
    • 34547756498 scopus 로고    scopus 로고
    • Evaluation of the research methodology in genetic, molecular and proteomic tests
    • Lumbreras B., Jarrin I., and Hernández-Aguado I. Evaluation of the research methodology in genetic, molecular and proteomic tests. Gac Sanit 20 (2006) 368-373
    • (2006) Gac Sanit , vol.20 , pp. 368-373
    • Lumbreras, B.1    Jarrin, I.2    Hernández-Aguado, I.3
  • 30
    • 1542358882 scopus 로고    scopus 로고
    • Methodology in diagnostic laboratory test research in clinical chemistry and clinical chemistry and laboratory medicine
    • Lumbreras-Lacarra B., Ramos-Rincon J.M., and Hernandez-Aguado I. Methodology in diagnostic laboratory test research in clinical chemistry and clinical chemistry and laboratory medicine. Clin Chem 50 (2004) 530-536
    • (2004) Clin Chem , vol.50 , pp. 530-536
    • Lumbreras-Lacarra, B.1    Ramos-Rincon, J.M.2    Hernandez-Aguado, I.3
  • 31
    • 33746060488 scopus 로고    scopus 로고
    • Use of biomarkers in epidemiologic studies: minimizing the influence of measurement error in the study design and analysis
    • Tworoger S.S., and Hankinson S.E. Use of biomarkers in epidemiologic studies: minimizing the influence of measurement error in the study design and analysis. Cancer Causes Control 17 (2006) 889-899
    • (2006) Cancer Causes Control , vol.17 , pp. 889-899
    • Tworoger, S.S.1    Hankinson, S.E.2
  • 32
    • 0035115925 scopus 로고    scopus 로고
    • Role of organochlorine compounds in the etiology of pancreatic cancer: a proposal to develop methodological standards
    • Porta M. Role of organochlorine compounds in the etiology of pancreatic cancer: a proposal to develop methodological standards. Epidemiology 12 (2001) 272-276
    • (2001) Epidemiology , vol.12 , pp. 272-276
    • Porta, M.1
  • 33
    • 34548014992 scopus 로고    scopus 로고
    • The influence of lipid and lifestyle factors upon correlations between highly prevalent organochlorine compounds in patients with exocrine pancreatic cancer
    • Porta M., Grimalt J.O., Jariod M., Ruiz L., Marco E., López T., et al. The influence of lipid and lifestyle factors upon correlations between highly prevalent organochlorine compounds in patients with exocrine pancreatic cancer. Environ Int 33 (2007) 946-954
    • (2007) Environ Int , vol.33 , pp. 946-954
    • Porta, M.1    Grimalt, J.O.2    Jariod, M.3    Ruiz, L.4    Marco, E.5    López, T.6
  • 34
    • 34548613771 scopus 로고    scopus 로고
    • Timing of blood extraction in epidemiologic and proteomic studies: results and proposals from the PANKRAS II Study
    • Porta M., Pumarega J., Ferrer-Armengou O., López T., Alguacil J., Malats N., et al. Timing of blood extraction in epidemiologic and proteomic studies: results and proposals from the PANKRAS II Study. Eur J Epidemiol 22 (2007) 577-588
    • (2007) Eur J Epidemiol , vol.22 , pp. 577-588
    • Porta, M.1    Pumarega, J.2    Ferrer-Armengou, O.3    López, T.4    Alguacil, J.5    Malats, N.6
  • 35
    • 0036135435 scopus 로고    scopus 로고
    • Pankras I Project Investigators. Generalizing molecular results arising from incomplete biological samples: expected bias and unexpected findings
    • Porta M., Malats N., Corominas J.M., Rifa J., Pinol J.L., and Real F.X. Pankras I Project Investigators. Generalizing molecular results arising from incomplete biological samples: expected bias and unexpected findings. Ann Epidemiol 12 (2002) 7-14
    • (2002) Ann Epidemiol , vol.12 , pp. 7-14
    • Porta, M.1    Malats, N.2    Corominas, J.M.3    Rifa, J.4    Pinol, J.L.5    Real, F.X.6
  • 36
    • 0036785169 scopus 로고    scopus 로고
    • Incomplete overlapping of biological, clinical and environmental information in molecular epidemiologic studies: a variety of causes and a cascade of consequences
    • Porta M., Malats N., Vioque J., Carrato C., Soler M., Ruiz L., et al. Incomplete overlapping of biological, clinical and environmental information in molecular epidemiologic studies: a variety of causes and a cascade of consequences. J Epidemiol Community Health 56 (2002) 734-738
    • (2002) J Epidemiol Community Health , vol.56 , pp. 734-738
    • Porta, M.1    Malats, N.2    Vioque, J.3    Carrato, C.4    Soler, M.5    Ruiz, L.6
  • 37
    • 0242629047 scopus 로고    scopus 로고
    • Assessment of the accuracy of diagnostic tests: the cross-sectional study
    • Knottnerus J.A., and Muris J.W. Assessment of the accuracy of diagnostic tests: the cross-sectional study. J Clin Epidemiol 56 (2003) 1118-1128
    • (2003) J Clin Epidemiol , vol.56 , pp. 1118-1128
    • Knottnerus, J.A.1    Muris, J.W.2
  • 38
    • 34347258494 scopus 로고    scopus 로고
    • Epidemiology
    • von Hoff D.D., Evans D.B., and Hruban R.H. (Eds), Jones & Bartlett, Boston, MA
    • Li D., Jiao L., and Porta M. Epidemiology. In: von Hoff D.D., Evans D.B., and Hruban R.H. (Eds). Pancreatic cancer (2005), Jones & Bartlett, Boston, MA 103-117
    • (2005) Pancreatic cancer , pp. 103-117
    • Li, D.1    Jiao, L.2    Porta, M.3
  • 39
    • 24044500647 scopus 로고    scopus 로고
    • Exocrine pancreatic cancer: symptoms at presentation and their relation to tumour site and stage
    • Porta M., Fabregat X., Malats N., Guarner L., Carrato A., de Miguel A., et al. Exocrine pancreatic cancer: symptoms at presentation and their relation to tumour site and stage. Clin Transl Oncol 7 (2005) 189-197
    • (2005) Clin Transl Oncol , vol.7 , pp. 189-197
    • Porta, M.1    Fabregat, X.2    Malats, N.3    Guarner, L.4    Carrato, A.5    de Miguel, A.6
  • 40
    • 35848937960 scopus 로고    scopus 로고
    • Porta M, Ferrer-Armengou O, Pumarega J, López T, Crous-Bou M, Alguacil A, et al. Exocrine pancreatic cancer clinical factors were related to timing of blood extraction and influenced serum concentrations of lipids. J Clin Epidemiol [in press].


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.