A quantum of neurotransmitter causes minis in multiple postsynaptic cells at the Caenorhabditis elegans neuromuscular junction

Developmental Neurobiology

Volumn 67, Issue 2, 2007, Pages 123-128

  Liu, Qiang ^a   Chen, Bojun ^a   Hall, David H ^b   Wang, Zhao Wen ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

C. elegans; Miniature postsynaptic current; Minis; Neuromuscular junction; Polyadic synapse

Indexed keywords

NEUROTRANSMITTER;

ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; CORRELATION ANALYSIS; MUSCLE CELL; NEUROMUSCULAR SYNAPSE; NONHUMAN; PRESYNAPTIC NERVE; PRIORITY JOURNAL; SYNAPSE; SYNAPTIC TRANSMISSION; VOLTAGE CLAMP;

ANALYSIS OF VARIANCE; ANIMALS; CAENORHABDITIS ELEGANS; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTRIC STIMULATION; EXCITATORY POSTSYNAPTIC POTENTIALS; NEUROMUSCULAR JUNCTION; NEUROTRANSMITTER AGENTS; PATCH-CLAMP TECHNIQUES; SYNAPSES; SYNAPTIC TRANSMISSION;

EID: 34548637935     PISSN: 19328451     EISSN: 1932846X     Source Type: Journal    
DOI: 10.1002/dneu.20307     Document Type: Article

References (16)

1. Barnes TM, Hekimi S. 1997. The Caenorhabditis elegans avermectin resistance and anesthetic response gene unc-9 encodes a member of a protein family implicated in electrical coupling of excitable cells. J Neurochem 69:2251-2260.
2. Chalfie M, White J. 1988. The nervous system. In: Wood WB and the Community of C. elegans Researchers, editors. The Nematode Caenorhabditis elegans. Plainview, NY: Cold Spring Harbor Laboratory Press, p 337-391.
3. Davis RE, Stretton AO. 1996. The motornervous system of Ascaris: electrophysiology and anatomy of the neurons and their control by neuromodulators. Parasitology 113 Suppl:S97-117.
4. de Bono M, Maricq AV. 2005. Neuronal substrates of complex behaviors in C. elegans. Annu Rev Neurosci 28:451-501.
5. Distler PG, Boeckh J. 1997. Synaptic connections between identified neuron types in the antennal lobe glomeruli of the cockroach, Periplaneta americana: I. Uniglomerular projection neurons. J Comp Neurol 378:307-319.
6. Dixon SJ, Roy PJ. 2005. Muscle arm development in Caenorhabditis elegans. Development 132:3079-3092.
7. Hall DH, Russell RL. 1991. The posterior nervous system of the nematode Caenorhabditis elegans: serial reconstruction of identified neurons and complete pattern of synaptic interactions. J Neurosci 11:1-22.
8. Jacobs K, Lakes-Harlan R. 2000. Pathfinding, target recognition, and synapse formation of single regenerating fibers in the adult grasshopper Schistocerca gregaria. J Neurobiol 42:394-409.
9. Liu Q, Chen B, Gaier E, Joshi J, Wang ZW. 2006. Low conductance gap junctions mediate specific electrical coupling in body-wall muscle cells of Caenorhabditis elegans. J Biol Chem 281:7881-7889.
10. Liu Q, Chen B, Yankova M, Morest DK, Maryon E, Hand AR, Nonet ML, et al. 2005. Ryanodine receptors are required for normal quantal size at the C. elegans neuromuscular junction. J Neurosci 25:6745-6754.
11. Rao-Mirotznik R, Buchsbaum G, Sterling P. 1998. Transmitter concentration at a three-dimensional synapse. J Neurophysiol 80:3163-3172.
12. Rao-Mirotznik R, Harkins AB, Buchsbaum G, Sterling P. 1995. Mammalian rod terminal: architecture of a binary synapse. Neuron 14:561-569.
13. Wang ZW, Saifee O, Nonet ML, Salkoff L. 2001. SLO-1 potassium channels control quantal content of neurotransmitter release at the C. elegans neuromuscular junction. Neuron 32:867-881.
14. Waterston RH. 1988. Muscle. In: Wood WB and the Community of C. elegans Researchers, editors. The Nematode Caenorhabditis elegans. Plainview, NY: Cold Spring Harbor Laboratory Press, p 281-335.
15. Watson AH, Schurmann FW. 2002. Synaptic structure, distribution, and circuitry in the central nervous system of the locust and related insects. Microsc Res Tech 56:210-226.
16. White JG, Southgate E, Thomson JN, Brenner S. 1986. The structure of the nervous system of the nematode Caenorhabditis elegans. Philos Trans R Soc Lond B Biol Sci 314:1-340.