Complex mixtures that may contain mutagenic and/or genotoxic components: a need to assess in vivo target-site effect(s) associated with in vitro-positive(s)

Chemosphere

Volumn 69, Issue 6, 2007, Pages 841-848

  Martin, Francis L ^a  

^a LANCASTER UNIVERSITY   (United Kingdom)

Author keywords

Complex mixtures; Genotoxicity; In vitro; In vivo; Mutagenicity; Risk assessment

Indexed keywords

CONCENTRATION (PROCESS); DNA; MUTAGENESIS; PHARMACOKINETICS; PROTEINS; RISK ASSESSMENT;

COMPLEX INTERACTIONS; COMPLEX MIXTURES; VIVO PROTOCOLS;

GENE EXPRESSION;

BIOLOGICAL MARKER; DNA;

CONCENTRATION (PROCESS); DNA; GENE EXPRESSION; MUTAGENESIS; PHARMACOKINETICS; PROTEINS; RISK ASSESSMENT;

ELECTROKINESIS; GENOTOXICITY; MUTAGENICITY; PHYSICOCHEMICAL PROPERTY; POLLUTION EFFECT; POLLUTION EXPOSURE; RISK ASSESSMENT;

CHROMOSOME DAMAGE; COMET ASSAY; DNA ADDUCT; DRUG MIXTURE; EPIGENETICS; GENE EXPRESSION; GENOTOXICITY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INFRARED SPECTROSCOPY; ISOTOPE LABELING; METABOLOMICS; MUTAGENICITY; NONHUMAN; PHYSICAL CHEMISTRY; POSITRON; PROTEOMICS; REVIEW; RISK ASSESSMENT; TARGET ORGAN;

EID: 34548633189     PISSN: 00456535     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2007.05.066     Document Type: Review

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