Evaluation of immobilization conditions for enhanced production of gentamicin in repeated batch operations by micromonospora echinospora

International Journal of Chemical Reactor Engineering

Volumn 5, Issue , 2007, Pages

  Meenavilli, Himabindu ^a   Potumarthi, Ravichandra ^a   Jetty, Annapurna ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

Ca alginate; Fluidized bed reactor; Gentamicin; Immobilization; Micromonospora; Repeated batch process

Indexed keywords

ACTIVATED CARBON; CALCIUM CHLORIDE; CELL IMMOBILIZATION; CONCENTRATION (PROCESS); FLUIDIZED BEDS; OPTIMIZATION; POLYURETHANES;

FLUIDIZED BED REACTORS; GENTAMICIN; MICROMONOSPORA; REPEATED BATCH PROCESSES;

ANTIBIOTICS;

EID: 34548631553     PISSN: 21945748     EISSN: 15426580     Source Type: Journal    
DOI: 10.2202/1542-6580.1467     Document Type: Article

References (41)

1. Adinarayana, K., Bapi Raju, K.V.V.S.N., Ellaiah, P., "Investigations on alkaline protease production with B. subtilis PE-11 immobilized in calcium alginate gel beads", Proc. Biochem., Vol. 39, 1331-1339 (2004).
2. Annapurna, J., Gangagni, R.A., Sarva, R.A., Madhavi, G., Ramakrishna, S.V., "Comparative Studies of Air Lift and Fluidized Bed Reactors for Streptomycin Production by Immobilized Cells of Streptomyces bikiniensis ATCC11062", Chem. Biochem. Eng., Vol. 19, 179-184 (2005).
3. Bandyopadhyay, A., Das, A,K., Mandai, S.K., "Erythromycin production by Streptomyces erythreus entrapped in calcium alginate beads", Biotechnol. Lett., Vol. 15, 1003-1006 (1993).
4. Born, C., Biselli, M., Wandrey, J., Thommes, J., Kula, M-R., "An approach to integrated antibody production: Coupling of fluidized bed cultivation and fluidized bed adsorption", Bioprocess. Biosys. Eng. Vol. 15, 21-19 (1996).
5. Chibata, I., Tosa, T., "Immobilized microbial cells and their applications", Trends, in Biochemical. Sciences., Vol. 5, 88-90 (1980).
6. Chibata, I., Tosa, T., Sato, T., Takata, I., "Immobilization of cells in carrageenan", Methods Enzymol., Vol. 135, 189-198 (1987).
7. Chu, J., Zhang, S., Zhuang, Y., Chen, J., Li, Y., "Factors affecting the biosynthesis and secretion of gentamicin", Process Bioche., Vol. 38, 815-820 (2002).
8. Chu, J., Niu, W., Zhang, S., Zhuang, Y., Hu, H., Li, Y., "Effect of metal ions on the binding of gentamicin to the peptidoglycan ofMicromonospora echinospora", Process Biochem., Vol. 39, 1145-1150 (2004).
9. Chun, G.T., Agathos, S.N., "Immobilization of Tolypocladium inflatum spores into porous celite beads for cyclosporin A production", J. Biotechnol, Vol. 9, 237-254 (1989).
10. Clarke, K., Hill, G.A., Pugsley, T.S., "Direct comparison of fluidized and packed bed bioreactors for bioremediation of an air pollutant", International Journal of Chemical Reactor Engineering., Vol. 5, art no. A11 (2007).
11. Davison, B.H., Scott, C. D., "Operability and Feasibility of Ethanol Production by Immobilized Zymomonas mobilis in a Fluidized-Bed Bioreactor," Appl. Biochem. Biotech., Vol. 18, 19-34 (1988).
12. El Sokkary, M., Habib, E., Hassan, R., EI-Emam, M.A., EI-Naggar, W.A., "Effect of some additives on gentamicin production by free and immobilized cells of M.purpurea" Mansoura. J. Pharm. Sci., Vol. 11, 170-187 (1995b).
13. El Sokkary, M., Habib, E., Hassan, R., EI-Naggar, W.A., "Gentamicin production by free and immobilized cells of M.purpurea", Mansoura. J. Pharm. Sci., Vol.11, 149-169 (1995a).
14. EI-Naggar, M.Y., Hassan, M.A., Said, W.Y., El-Aassar, S.A., "Effect of support materials on antibiotic MSW2000 production by immobilized Streptomyces violants" J. Gen. Appl. Microbiol, Vol. 49, 235-243 (2003).
15. Fan, L.S., "Gas-Liquid-Solid Fluidization Engineering". Eds., Butter Worth, Stoneham. (1989).
16. Ferreer, P., Sola, C., "Lipase production by immobilized Candida rugosa cells", Appl. Micro. Biotech. Vol. 37, 737-741 (1992).
17. Groboillot, A.F, Boadi, D.K, Poncelet, D., Neufeld, R.J., "Immobilization of cells for application in the food industry", Crit. Rev. Biotechnol, Vol. 14, 75-108 (1994).
18. Hashimoto, S., Furukawa, K., "Immobilization of activated sludge by PVA-boric acid method", Biotechnol. Bioeng., Vol. 30, 52-9 (1987).
19. Himabindu, M., Annapurna, J., "Optimization of nutritional requirements for gentamicin production by Micromonospora echinospora", Ind. J. Experim. Biol, Vol. 44, 842-848 (2006).
20. Himabindu, M., Ravichandra, P., Vishalakshi., Annapurna, J., "Optimization of critical medium components for the maximal production of gentamicin by Micromonospora echinospora ATCC 15838 using response surface methodology". Appl. Biochem. Biotechnol., Vol. 134, 143-154 (2006).
21. Himabindu, M., Potumarthi, R., Jetty, A., "Enhancement of gentamicin production by mutagenesis and non nutritional stress conditions in Micromonospora echinospora". Process Biochem. doi:10.1016/j.procbio. 2007.05.002, In Press (2007).
22. Hinterleitner, P., Unterluggauer, F., Landauer, K., Müller, D., Kunert, R., Blüml, G., Doblhoff-Dier, O., Katinger, H., "Comparison of Fluidized Bed and Fed Batch Reactor Cultures for Production of Anti-HIV-Antibody", Animal Cell Tech. Meets Senomocs. Vol. 2, 253-255 (2005).
23. Jamuna, R., Sai, P., Vora, S., Ramakrishna, S,V., "Optimization of critical parameters for immobilization of yeast cells to alginate gel matrix", J. Ferment. Bioeng., Vol. 4, 319-322 (1992).
24. Keshvarz, T., Eglin, R., Walker, E., Bucke, C., Holt, G., Bull, A.T., Lilly, M.D., "The large scale immobilization of Pencillium chryosogenum: Batch and continuous operation in an air-lift reactor", Biotechnol. Bioeng., Vol. 36, 763-770 (1990).
25. Kim, D.J., Chang, H.N., "Enhanced shikonin production from Lithospermum erythrohizon by in situ extraction and calcium alginate immobilization", Biotechnol. Bioeng., Vol. 36, 460-466.
26. Kim, J.H., Oh, D.K., Park, S.K., Park, Y.H., Wallis, D.A., "Production of penicillin in a fluidized bed bioreactor using a carrier supported mycelial growth", Biotechnol. Bioeng., Vol. 28, 1838-44 (1986).
27. Kopp, B., Rehm, H., "Alkaloid production by immobilized mycelia of Claviceps purpura", Eur. J. Appl. Microbiol. Biotechnol., Vol. 8, 237-263 (1983).
28. Krishnan, M.S., Nghiem, N., Davison, B.H., "Ethanol production from corn starch in a fluidized-bed bioreactor", Appl. Biochem. Biotech. Vol. 78, 359-372 (1999).
29. Lin, J., Zhou, M., Zhao, X., Luo, S. and Lu, Y., "Extractive fermentation of L-lactic acid with immobilized Rhizopus oryzae in a three-phase fluidized bed", Chemical Eng. Processing., Vol. 46, 369-374 (2007).
30. Luedemann, G.M.and Weinstein, M.J. Gentamycin and method of production. US Patent 3,091,572 (Schering Corporation, Bloomfield, N.J 28 May 1963), (1963).
31. Mina, D., "Production of actinomycin D with immobilized Streptomyces parvullus under nitrogen and carbon starvation conditions", Biotechnol. Letters., Vol. 10, 40-45 (1988).
32. Nilsson, K., Mosbach, K., "Preparation of immobilized animal cells", FEBS Lett., Vol. 118, 145-150 (1980).
33. Ohlson, S., Flagare, S., Larsson, P., Mosbach, R., "Steroid hydroxylation using immobilized spores of Curvularia lunata germinated in situ", Eur. J. Appl. Microbiol. Biotechnol., Vol. 10, 1-10 (1980).
34. Ravichandra, P., Jetty, A., Jpseph, J., Rao, A.G., "Oxygen transfer rate in continuous multi phase fluidized bed reactor with immobilized cells of Streptomyces varsoviensis for production of Oxytetracycline", Biosci. Biotech. Res. Asia., Vol. 3, 333-340 (2006).
35. Sanchez, S., Mateos, R.C., Paniagua, L., Lara, F., Mora, J., "Nitrogen regulation of penicillin G production in Pencillium chrysogenum" in "Fermentation products", Young, M.M., Venzina. Eds., Pergamon Press, Toronto, 147-154 (1981).
36. Umemura, I., Takamatsu, S., Sato, T., Tosa, T., Chibata, I., "Improvement of production of L-aspartic acid using immobilised microbial cells", Appl. Microbial. Biotechnol., Vol. 20, 291-295 (1984).
37. Veelken, M., Pape, H., "Production of tylosin and nikkomycin by immobilized Streptomyces cells", Eur. J. Appl. Microbio. Biotech., Vol. 15, 206-210 (1982).
38. Wagman, G.H., Weinstein, M.J., "Antibiotics from Micromonospora", Annual. Rev. Microbial, Vol. 34, 537-557 (1980).
39. Weinstein, M.J., Luedemann, G.M., Oden, E.M., Wagman, G.H., Rosselet, J.P., Marquez, J.A., Coniglio, C.T, Charney, W., Herzog, H.L., Black, J., "Gentamicin, new antibiotic complex from Micromonospora", J. Med. Chem., Vol. 6, 463-464 (1963).
40. Woodward, J., "Immobilised enzymes: adsorption and covalent" in "Immobilised Cells and Enzymes" Woodward, J. Eds., Oxford Press, Washington, DC, 3-17 (1985).
41. Yang, S.S., Yueh, C.Y., "Oxytetracycline production by immobilized Streptomyces rimosus", J. Microbial. Immunol. Infect., Vol. 34, 235-242 (2001).