Herpes simplex virus type 1 ICP4 deletion mutant virus d120 infection failed to induce apoptosis in nerve growth factor-differentiated PC12 cells

Journal of NeuroVirology

Volumn 13, Issue 4, 2007, Pages 305-314

  Aiamkitsumrit, Benjamas ^a   Zhang, Xianchao ^a   Block, Timothy ^a   Norton, Pamela ^a   Fraser, Nigel ^b   Su, Ying Hsiu ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

HSV 1 infection in neuron; ICP4 deletion mutant; NF kappa; Viral induced apoptosis

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NERVE GROWTH FACTOR; PROTEIN ICP4; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL COUNT; CELL DIFFERENTIATION; CONTROLLED STUDY; GENE DELETION; GENETIC CODE; HEP 2 CELL; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; NERVE CELL NECROSIS; NONHUMAN; PHEOCHROMOCYTOMA CELL; PRIORITY JOURNAL; PROTEIN INTERACTION; VERO CELL; VIRUS GENOME; VIRUS STRAIN; WILD TYPE;

ANIMALS; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL DIFFERENTIATION; CELL LINE, TUMOR; CERCOPITHECUS AETHIOPS; GENE DELETION; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; HUMANS; IMMEDIATE-EARLY PROTEINS; KIDNEY NEOPLASMS; NERVE GROWTH FACTOR; NEURONS; PC12 CELLS; PROTEIN-SERINE-THREONINE KINASES; RATS; TRANSCRIPTION FACTOR RELA; VERO CELLS; VIRAL PROTEINS;

HUMAN HERPESVIRUS 1;

EID: 34548626219     PISSN: 13550284     EISSN: None     Source Type: Journal    
DOI: 10.1080/13550280701361490     Document Type: Article

References (36)

1. Amici, C., Belardo, G., Rossi, A. and Santoro, M. G. (2001) Activation of Ikappa B kinase by herpes simplex virus type 1. A novel target for anti-herpetic therapy. J Biol Chem, 276, pp. 28759-28766.
2. Amici, C., Belardo, G., Rozera, C., Bernasconi, D. and Santoro, M. G. (2004) Inhibition of herpesvirus-induced HIV-1 replication by cyclopentenone prostaglandins: Role of I[kappa]B kinase (IKK). AIDS, 18, pp. 1271-1280.
3. Aubert, M. and Blaho, J. A. (1999) The herpes simplex virus type 1 regulatory protein ICP27 is required for the prevention of apoptosis in infected human cells. J Virol, 73, pp. 2803-2813.
4. Azoitei, N., Wirth, T. and Baumann, B. (2005) Activation of the IkappaB kinase complex is sufficient for neuronal differentiation of PC12 cells. J Neurochem, 93, pp. 1487-1501.
5. Chou, J. and Roizman, B. (1992) The gamma34.5 gene of herpes simplex virus 1 precludes neuroblastoma cells from triggering total shutoff of protein synthesis characteristic of programmed cell death in neuronal cells. Proc Natl Acad Sci U S A, 89, pp. 3266-3270.
6. Cui, C., Griffiths, A., Silva, L. M., Kramer, M. F., Gaasterland, T., Wang, X. J. and Coen, D. M. (2006) Prediction and identification of herpes simplex virus 1-encoded microRNAs. J Virol, 80, pp. 5499-5508.
7. DeLuca, N. A., McCarthy, A. and Schaffer, P. A. (1985) Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4. J Virol, 56, pp. 558-570.
8. Galvan, V., Brandimarti, R. and Roizman, B. (1999) Herpes simplex virus 1 blocks caspase-3-independent and caspase-dependent pathways to cell death. J Virol, 73, pp. 3219-3226.
9. Galvan, V. and Roizman, B. (1998) Herpes simplex virus 1 induces and blocks apoptosis at multiple steps during infection and protects cells from exogenous inducers in a cell-type-dependent manner. Proc Natl Acad Sci U S A, 95, pp. 3931-3936.
10. Ghosh, S., May, M. J. and Kopp, E. B. (1998) NF-κ B and REL proteins: Evolutionarily conservedmediators of immune responses. Annu Rev Immunol, 16, pp. 225-260.
11. Goodkin, M. L., Ting, A. T. and Blaho, J. A. (2003) NF-kappaB is required for apoptosis prevention during herpes simplex virus type 1 infection. J Virol, 77, pp. 7261-7280.
12. Greene, L. A. and Tischler, A. S. (1976) Establishment of a nonadrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci U S A, 73, pp. 2424-2428.
13. Gregory, D., Hargett, D., Holmes, D., Money, E. and Bachenheimer, S. L. (2004) Efficient replication by herpes simplex virus type 1 involves activation of the IkappaB kinase-IkappaB-p65 pathway. J Virol, 78, pp. 13582-13590.
14. Gupta, A., Gartner, J. J., Sethupathy, P., Hatzigeorgiou, A. G. and Fraser, N. W. (2006) Anti-apoptotic function of a microRNA encoded by the HSV-1 latency-associated transcript. Nature, 442, pp. 82-85.
15. Ishige, K., Tanaka, M., Arakawa, M., Saito, H. and Ito, Y. (2005) Distinct nuclear factor-[kappa]B/Rel proteins have opposing modulatory effects in glutamate-induced cell death in HT22 cells. Neurochem Int, 47, pp. 545-555.
16. Jerome, K. R., Fox, R., Chen, Z., Sears, A. E., Lee, H. Y. and Corey, L. (1999) Herpes simplex virus inhibits apoptosis through the action of two genes, Us5 and Us3. J Virol, 73, pp. 8950-8957.
17. Koyama, A. H., Fukumori, T., Fujita, M., Irie, H. and Adachi, A. (2000) Physiological significance of apoptosis in animal virus infection. Microb Infect, 2, pp. 1111-1117.
18. Leopardi, R. and Roizman, B. (1996) The herpes simplex virus major regulatory protein ICP4 blocks apoptosis induced by the virus or by hyperthermia. Proc Natl Acad Sci U S A, 93, pp. 9583-9587.
19. Leopardi, R., Van Sant, C. and Roizman, B. (1997) The herpes simplex virus 1 protein kinase US3 is required for protection from apoptosis induced by theávirus. Proc Natl Acad Sci U S A, 94, pp. 7891-7896.
20. Medici, M. A., Sciortino, M. T., Perri, D., Amici, C., Avitabile, E., Ciotti, M., Balestrieri, E., De Smaele, E., Franzoso, G. and Mastino, A. (2003) Protection by herpes simplex virus glycoprotein D against Fas-mediated apoptosis: Role of nuclear factor kappaB. J Biol Chem, 278, pp. 36059-36067.
21. Moxley, M., Block, T., Liu, H-C, Fraser, N., Perng, G-C, Wechsler, S. and Su, Y-H (2002) Herpes simplex virus type 1 infection prevents detachment of nerve growth factor-differentiated PC12 cells in culture. J Gen Virol, 83, pp. 1591-1600.
22. Munger, J., Chee, A. and Roizman, B. (2001) The Us3 protein kinase blocks apoptosis induced by the d120 mutant of herpes simplex virus 1 at premitochondrial stage. J Virol, 75, pp. 5491-5497.
23. Ono, T., Sekino-Suzuki, N., Kikkawa, Y., Yonekawa, H. and Kawashima, S. (2003) Alivin 1, a novel neuronal activity-dependent gene, inhibits apoptosis and promotes survival of cerebellar granule neurons. J Neurosci, 23, pp. 5887-5896.
24. Patel, A., Hanson, J., McLean, T. I., Olgiate, J., Hilton, M., Miller, W. E. and Bachenheimer, S. L. (1998) Herpes simplex virus type 1 induction of persistent NF-[kappa]B nuclear translocation increases the efficiency of virus replication. Virology, 247, pp. 212-222.
25. Pizzi, M., Goffi, F., Boroni, F., Benarese, M., Perkins, S. E., Liou, H. C. and Spano, P. (2002) Opposing roles for NF-kappa B/Rel Factors p65 and c-Rel in the modulation of neuron survival elicited by glutamate and interleukin-1beta. J Biol Chem, 277, pp. 20717-20723.
26. Santoro, M. G., Rossi, A. and Amici, C. (2003) NF-kB and virus infection: Who controls whom. EMBO J, 22, pp. 2552-2560.
27. Su, Y-H, Meegalla, R. L., Chowan, R., Cubitt, C., Oakes, J. E., Lausch, R. L., Fraser, N. W. and Block, T. M. (1999) Human corneal cells and other fibroblasts can stimulate the appearance of herpes simplex virus from quiescently infected PC12 cells. J Virol, 73, pp. 4171-4180.
28. Su, Y-H, Moxley, M., Kejariwal, R., Mehta, A., Fraser, N. W. and Block, T. M. (2000) The HSV 1 genome in quiescently infected NGF differentiated PC12 cells can not be stimulated by HSV superinfection. J NeuroVirol, 6, pp. 341-349.
29. Su, Y-H, Moxley, M., Ng, A. K., Lin, J., Jordan, R., Fraser, N. W. and Block, T. M. (2002) Stability and circularization of herpes simplex virus type 1 genomes in quiescently infected PC12 cultures. J Gen Virol, 83, pp. 2943-2950.
30. Taddeo, B., Esclatine, A. and Roizman, B. (2002) The patterns of accumulation of cellular RNAs in cells infected with a wild-type and a mutant herpes simplex virus 1 lacking the virion host shutoff gene. Proc Natl Acad Sci U S A, 99, pp. 17031-17036.
31. Taddeo, B., Luo, T. R., Zhang, W. and Roizman, B. (2003) Activation of NF-kappaB in cells productively infected with HSV-1 depends on activated protein kinase R and plays no apparent role in blocking apoptosis. Proc Natl Acad Sci U S A, 100, pp. 12408-12413.
32. Taddeo, B., Zhang, W., Lakeman, F. and Roizman, B. (2004) Cells lacking NF-kappaB or in which NF-kappaB is not activated vary with respect to ability to sustain herpes simplex virus 1 replication and are not susceptible to apoptosis induced by a replication-incompetent mutant virus. J Virol, 78, pp. 11615-11621.
33. Yedowitz, J. C. and Blaho, J. A. (2005) Herpes simplex virus 2 modulates apoptosis and stimulates NF-[kappa]B nuclear translocation during infection in human epithelial HEp-2 cells. Virology, 342, pp. 297-310.
34. Zhou, G., Galvan, V., Campadelli-Fiume, G. and Roizman, B. (2000) Glycoprotein D or J delivered in trans blocks apoptosis in SK-N-SH cells induced by a herpes simplex virus 1 mutant lacking intact genes expressing both glycoproteins. J Virol, 74, pp. 11782-11791.
35. Zhou, G. and Roizman, B. (2000) Wild-type herpes simplex virus 1 blocks programmed cell death and release of cytochrome c but not the translocation of mitochondrial apoptosis-inducing factor to the nuclei of human embryonic lung fibroblasts. J Virol, 74, pp. 9048-9053.
36. Zhou, G. and Roizman, B. (2001) The domains of glycoprotein D required to block apoptosis depend on whether glycoprotein D is present in the virions carrying herpes simplex virus 1 genome lacking the gene encoding the glycoprotein. J Virol, 75, pp. 6166-6172.