The trouble with animal models

Scientist

Volumn 21, Issue 7, 2007, Pages 45-51

  Gawrylewski, Andrea ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

EID: 34548624501     PISSN: 08903670     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (5)

1. S. Savitz, "A critical appraisal of the NXY-059 neuroprotection studies for acute stroke: a need for more rigorous testing of neuroprotective agents in animal models of stroke," Exper Neurol, 205:20-5, May 2007.
2. V. Bebarta et al., "Emergency medicine research: Does use of randomization and blinding affect the results?" Acad Emerg Med, 10:684-7, 2003.
3. P. Perel et al., "Comparison of treatment effects between animal experiments and clinical trials: systematic review," Brit Med J, 334:197, Jan. 27, 2007.
4. I.R. Mackensie et al., "Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations," Ann Neurol, 61:427-34, May 2007.
5. D.T. Odom et al., "Tissue-specific transcriptional regulation has diverged significantly between human and mouse," Nat Genet, 39:730-2, June 2007.