SCOPUS 정보 검색 플랫폼

Journal of Natural Products

Volumn 70, Issue 8, 2007, Pages 1253-1258

Transformations of manool. tri- and tetracyclic norditerpenoids with in vitro activity against Plasmodium falciparum

(5) Van Wyk, Albert W W a Lobb, Kevin A a Caira, Mino R b Hoppe, Heinrich C c Davies Coleman, Michael T a

a RHODES UNIVERSITY (South Africa)

b UNIVERSITY OF CAPE TOWN (South Africa)

c UNIVERSITY OF CAPE TOWN (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

17 NORABIET 13 ENE 8BETA,16 DIOL; 17 NORISOPIMAR 15 ENE 8BETA,13BETA DIOL; 17 NORISOPIMARANE 8BETA,15 DIOL; 17 NORPIMARAN 13ALPHA ETHOXY 8,16 OLACTONE; ANTIPROTOZOAL AGENT; DITERPENOID; ETHYL 17 NORABIET 13 EN 8BETA OL 16 OIC ACID; MANOOL; NATURAL PRODUCT; REAGENT; UNCLASSIFIED DRUG;

ANTIPROTOZOAL ACTIVITY; ARTICLE; BIOTRANSFORMATION; CONCENTRATION RESPONSE; IN VITRO STUDY; NONHUMAN; PLASMODIUM FALCIPARUM; SPECTROSCOPY; STANDARD; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTIMALARIALS; CRYSTALLOGRAPHY, X-RAY; DITERPENES; ERYTHROCYTES; HUMANS; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PLASMODIUM FALCIPARUM;

PLASMODIUM FALCIPARUM;

EID: 34548616882 PISSN: 01633864 EISSN: None Source Type: Journal
DOI: 10.1021/np0701071 Document Type: Article

Times cited : (10)

References (26)

1
- 15044338866
- Snow, R. W.; Guerra, C. A.; Noor, A. M.; Myint, H. Y.; Hay, S. I. Nature 2005, 434, 214-217.
- (2005) Nature , vol.434 , pp. 214-217
- Snow, R.W.¹ Guerra, C.A.² Noor, A.M.³ Myint, H.Y.⁴ Hay, S.I.⁵

2
- 0037033984
- Sachs, J.; Malaney, P. Nature 2002, 415, 680-685.
- (2002) Nature , vol.415 , pp. 680-685
- Sachs, J.¹ Malaney, P.²

3
- 0037034009
- Ridley, R. G. Nature 2002, 415, 686-693.
- (2002) Nature , vol.415 , pp. 686-693
- Ridley, R.G.¹

4
- 0031847073
- Foley, M.; Tilley, L. Pharmacol. Ther. 1998, 79, 55-87.
- (1998) Pharmacol. Ther , vol.79 , pp. 55-87
- Foley, M.¹ Tilley, L.²

5
- 23944451082
- Mutabingwa, T. K. Acta Trop. 2005, 95, 305-315.
- (2005) Acta Trop , vol.95 , pp. 305-315
- Mutabingwa, T.K.¹

6
- 13844276627
- Sams-Dodd, F. Drug Discovery Today 2005, 10, 139-147.
- (2005) Drug Discovery Today , vol.10 , pp. 139-147
- Sams-Dodd, F.¹

7
- 0035179157
- Tagboto, S.; Townson, S. Adv. Parasitol. 2001, 50, 199-295.
- (2001) Adv. Parasitol , vol.50 , pp. 199-295
- Tagboto, S.¹ Townson, S.²

8
- 2042465925
- Asili, J.; Lambert, M.; Ziegler, H. L.; Staerk, D.; Sairafianpour, M.; Witt, M.; Asghari, G.; Ibrahimi, I. S.; Jaroszewski, J. W. J. Nat. Prod. 2004, 67, 631-637.
- (2004) J. Nat. Prod , vol.67 , pp. 631-637
- Asili, J.¹ Lambert, M.² Ziegler, H.L.³ Staerk, D.⁴ Sairafianpour, M.⁵ Witt, M.⁶ Asghari, G.⁷ Ibrahimi, I.S.⁸ Jaroszewski, J.W.⁹

9
- 31544476908
- Villamizar, J.; Plata, F.; Canudas, N.; Tropper, E.; Fuentes, J.; Orcajo, A. Syn. Commun. 2006, 36, 311-320.
- (2006) Syn. Commun , vol.36 , pp. 311-320
- Villamizar, J.¹ Plata, F.² Canudas, N.³ Tropper, E.⁴ Fuentes, J.⁵ Orcajo, A.⁶

10
- 33645988178
- Vik, A.; Hedner, E.; Charnock, C.; Samuelsen, O.; Larsson, R.; Gundersen, L.-L.; Bohlin, L. J. Nat. Prod. 2006, 69, 381-386.
- (2006) J. Nat. Prod , vol.69 , pp. 381-386
- Vik, A.¹ Hedner, E.² Charnock, C.³ Samuelsen, O.⁴ Larsson, R.⁵ Gundersen, L.-L.⁶ Bohlin, L.⁷

11
- 0347026018
- Villamizar, J.; Fuentes, J.; Salazar, F.; Tropper, E.; Alonso, R. J. Nat. Prod. 2003, 66, 1623-1627.
- (2003) J. Nat. Prod , vol.66 , pp. 1623-1627
- Villamizar, J.¹ Fuentes, J.² Salazar, F.³ Tropper, E.⁴ Alonso, R.⁵

12
- 0000914129
- Buckwalter, B. L.; Burfitt, I. R.; Felkin, H.; Joly-Goudket, M.; Naemura, K.; Salomon, M. F.; Wenkert, E.; Wovkulich, P. M. J. Am. Chem. Soc. 1978, 100, 6445-6450.
- (1978) J. Am. Chem. Soc , vol.100 , pp. 6445-6450
- Buckwalter, B.L.¹ Burfitt, I.R.² Felkin, H.³ Joly-Goudket, M.⁴ Naemura, K.⁵ Salomon, M.F.⁶ Wenkert, E.⁷ Wovkulich, P.M.⁸

13
- 0000170665
- Wenkert, E.; Mahajan, J. R.; Nussim, M.; Schenker, F. Can. J. Chem. 1966, 44, 2575-2579.
- (1966) Can. J. Chem , vol.44 , pp. 2575-2579
- Wenkert, E.¹ Mahajan, J.R.² Nussim, M.³ Schenker, F.⁴

14
- 34147111172
- Do Khac Manh, D.; Fetizon, M.; Flament, J. P. Tetrahedron 1975, 31, 1897-1902.
- (1975) Tetrahedron , vol.31 , pp. 1897-1902
- Do Khac Manh, D.¹ Fetizon, M.² Flament, J.P.³

15
- 0000432259
- Sundararaman, P.; Herz, W. J. Org. Chem. 1977, 42, 813-819.
- (1977) J. Org. Chem , vol.42 , pp. 813-819
- Sundararaman, P.¹ Herz, W.²

16
- 0001848341
- For reviews of the HWE reaction see: a
- For reviews of the HWE reaction see: (a) Maryanoff, B. E.; Reitz, A. B. Chem. Rev. 1989, 89, 863-927.
- (1989) Chem. Rev , vol.89 , pp. 863-927
- Maryanoff, B.E.¹ Reitz, A.B.²

17
- 33847803678
- (b) Boutagy, J.; Thomas, R. Chem. Rev. 1974, 74, 87-99.
- (1974) Chem. Rev , vol.74 , pp. 87-99
- Boutagy, J.¹ Thomas, R.²

18
- 0012117301
- Trost, B. M, Ed, Pergamon: Oxford
- Kelly S. E. In Alkene Synthesis. Comparative Organic Synthesis; Trost, B. M., Ed.; Pergamon: Oxford, 1991; Vol. 1, pp 761-773.
- (1991) Alkene Synthesis. Comparative Organic Synthesis , vol.1 , pp. 761-773
- Kelly, S.E.¹

19
- 34548659391
- Manitto, P. In Biosynthesis of Natural Products; Sammes, P. G., Translation Ed.; Ellis Horwood Ltd.: Chichester, 1981; pp 257-260.
- Manitto, P. In Biosynthesis of Natural Products; Sammes, P. G., Translation Ed.; Ellis Horwood Ltd.: Chichester, 1981; pp 257-260.

20
- 34548649417
- X-ray analysis of 6. Diffraction intensities were collected with Mo Kα radiation from a cubic fragment (0.10 x 0.11 x 0.12 mm3) using φ- and ω-scans of 1.00° on a Nonius Kappa CCD diffractometer, with the crystal cooled to 113(2) K in a nitrogen stream. Crystal data for 6: C21H34O3, M, 334.48, orthorhombic, space group P21212 1 (no. 19, a, 7.3750(2) Å, b, 9.7769(3) Å, c, 27.077(1) Å, V, 1952.4(1) Å3, Z, 4, Dc, 1.138 Mg/m3, μ(Mo Kα, 0.074 mm-1, F(000, 736. A total of 4302 reflections were collected, of which 2405 were observed [I > 2σI, The structure was solved by direct methods and refined on F2 using all data, with non-hydrogen atoms treated anisotropically. All H atoms were located
- 2 = 0.0917 (all data), 0.0742 (observed data) for 222 parameters. Crystallographic data (excluding structure factors) have been deposited at the Cambridge Crystallographic Data Centre (deposition no. 620303).

21
- 34548609582
- X-ray analysis of 8. Diffraction intensities were collected with Mo Kα radiation from a specimen of dimensions 0.10 x 0.20 x 0.20 mm 3 using φ- and ω-scans of 1.00° on a Nonius Kappa CCD diffractometer, with the crystal cooled to 113(2) K in a nitrogen stream. Crystal data for 8: C21H34O3, M, 334.48, monoclinic, space group P21 (no. 4, a, 6.9880(1) Å, b, 22.0165(4) Å, c, 12.6710-(3) Å, β, 101.345(1)°, V, 1911.36(6) Å3, Z, 4, Dc, 1.162 Mg/m3, μ(Mo Kα, 0.075 mm-1, F(000, 736. A total of 8635 reflections were collected, of which 5846 were observed [I > 2σ-I, The structure was solved by direct methods and refined on F2 using all data, with non-hydrogen atoms treated anisotropically. All H atoms were
- 2 = 0.0782 (all data), 0.0692 (observed data) for 441 parameters. Crystallographic data (excluding structure factors) have been deposited at the Cambridge Crystallographic Data Centre (deposition no. 620304).

22
- 0037168535
- Lim, G. H. W.; Wortis, M.; Mukhopadhyay, R. Proc. Natl. Acad. Sci. U.S.A. 2002, 99, 16766-16769.
- (2002) Proc. Natl. Acad. Sci. U.S.A , vol.99 , pp. 16766-16769
- Lim, G.H.W.¹ Wortis, M.² Mukhopadhyay, R.³

23
- 0034624597
- Ravn, M. M.; Coates, R. M.; Flory, J. E.; Peters, R. J.; Croteau, R. Org. Lett. 2000, 2, 573-576.
- (2000) Org. Lett , vol.2 , pp. 573-576
- Ravn, M.M.¹ Coates, R.M.² Flory, J.E.³ Peters, R.J.⁴ Croteau, R.⁵

24
- 0021143095
- Bastard, J.; Duc, D. K.; Fetizon, M. J. Nat. Prod. 1984, 47, 592-599.
- (1984) J. Nat. Prod , vol.47 , pp. 592-599
- Bastard, J.¹ Duc, D.K.² Fetizon, M.³

25
- 37049075557
- Saragiotto, M. H.; Gower, A. E.; Marsaioli, A. J. J. Chem. Soc., Perkin Trans. 1 1989, 559-562.
- (1989) J. Chem. Soc., Perkin Trans. 1 , pp. 559-562
- Saragiotto, M.H.¹ Gower, A.E.² Marsaioli, A.J.³

26
- 0027394203
- Makler, M. T.; Hinrichs, D. J. Am. J. Trap. Med. Hyg. 1993, 48, 205-210.
- (1993) Am. J. Trap. Med. Hyg , vol.48 , pp. 205-210
- Makler, M.T.¹ Hinrichs, D.J.²

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.