Predicting odor pleasantness from odorant structure: Pleasantness as a reflection of the physical world

Journal of Neuroscience

Volumn 27, Issue 37, 2007, Pages 10015-10023

  Khan, Rehan M ^a,b   Luk, Chung Hay ^a   Flinker, Adeen ^a   Aggarwal, Amit ^a   Lapid, Hadas ^b   Haddad, Rafi ^b   Sobel, Noam ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Hedonics; Odor; Olfaction; Pleasantness; Smell; Valence

Indexed keywords

ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN EXPERIMENT; LEARNING; MALE; ODOR; OLFACTORY SYSTEM; PERCEPTION; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SMELLING;

ADULT; CROSS-CULTURAL COMPARISON; ENVIRONMENT; FEMALE; HUMANS; MALE; ODORS; PREDICTIVE VALUE OF TESTS; REACTION TIME; RECEPTORS, ODORANT; RECOGNITION (PSYCHOLOGY); SENSORY THRESHOLDS; SMELL;

EID: 34548610239     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1158-07.2007     Document Type: Article

References (63)

1. Abraham NM, Spors H, Carleton A, Margrie TW, Kuner T, Schaefer AT (2004) Maintaining accuracy at the expense of speed: stimulus similarity defines odor discrimination time in mice. Neuron 44:865-876.
2. Amoore JE (1963) Stereochemical theory of olfaction. Nature 198:271-272.
3. Anderson AK, Christoff K, Stappen I, Panitz D, Ghahremani DG, Glover G, Gabrieli JD, Sobel N (2003) Dissociated neural representations of intensity and valence in human olfaction. Nat Neurosci 6:196-202.
4. Ayabe-Kanamura S, Schicker I, Laska M, Hudson R, Distel H, Kobayakawa T, Saito S (1998) Differences in perception of everyday odors: a Japanese-German cross-cultural study. Chem Senses 23:31-38.
5. Barkai E (2005) Dynamics of learning-induced cellular modifications in the cortex. Biol Cybern 92:360-366.
6. Bensafi M, Pierson A, Rouby C, Farget V, Bertrand B, Vigouroux M, Jouvent R, Holley A (2002) Modulation of visual event-related potentials by emotional olfactory stimuli. Neurophysiol Clin 32:335-342.
7. Berglund B, Berglund U, Engen T, Ekman G (1973) Multidimensional analysis of 21 odors. Scandinavian J Psychol 14:131-137.
8. Brennan PA, Keverne EB (1997) Neural mechanisms of mammalian olfactory learning. Prog Neurobiol 51:457-481.
9. Cain WS (1969) Odor intensity. Differences in exponent of psychophysical function. Percept Psychophys 6:349-354.
10. Cain WS, Johnson Jr F (1978) Lability of odor pleasantness: influence of mere exposure. Perception 7:459-465.
11. Critchley HD, Rolls ET (1996) Hunger and satiety modify the responses of olfactory and visual neurons in the primate orbitofrontal cortex. J Neurophysiol 75:1673-1686.
12. Davis RL (2004) Olfactory learning. Neuron 44:31-48.
13. de Araujo IE, Rolls ET, Velazco MI, Margot C, Cayeux I (2005) Cognitive modulation of olfactory processing. Neuron 46:671-679.
14. Dielenberg RA, McGregor IS (2001) Defensive behavior in rats towards predatory odors: a review. Neurosci Biobehav Rev 25:597-609.
15. Doty RL (1975) An examination of relationships between the pleasantness, intensity and concentration of 10 odorous stimuli. Percept Psychophysiol 492-496.
16. Dravnieks A (1982) Odor quality: semantically generated multidimensional profiles are stable. Science 218:799-801.
17. Dravnieks A (1985) Atlas of odor character profiles. Philadelphia, PA: ASTM.
18. Dravnieks A, Masurat T, Lamm RA (1984) Hedonics of odors and odor descriptors. J Air Pollut Control Assoc 34:752-776.
19. Engen T (1982) The perception of odors. New York: Academic.
20. Godinot N, Sicard G (1995) Odor categorization by human-subjects: an experimental approach. Chem Senses 20:101.
21. Gottfried JA, Dolan RJ (2003) The nose smells what the eye sees: crossmodal visual facilitation of human olfactory perception. Neuron 39:375-386.
22. Gottfried JA, Deichmann R, Winston JS, Dolan RJ (2002) Functional heterogeneity in human olfactory cortex: an event-related functional magnetic resonance imaging study. J Neurosci 22:10819-10828.
23. Graziadei PP, Levine RR, Monti Graziadei GA (1979) Plasticity of connections of the olfactory sensory neuron: regeneration into the forebrain following bulbectomy in the neonatal mouse. Neuroscience 4:713-727.
24. Haberly LB (2001) Parallel-distributed processing in olfactory cortex: new insights from morphological and physiological analysis of neuronal circuitry. Chem Senses 26:551-576.
25. Henion KE (1971) Odor pleasantness and intensity: a single dimension? J Exp Psychol 90:275-279.
26. Herz RS, von Clef J (2001) The influence of verbal labeling on the perception of odors: evidence for olfactory illusions? Perception 30:381-391.
27. Hudson R (1999) From molecule to mind: the role of experience in shaping olfactory function. J Comp Physiol A Neuroethol Sens Neural Behav Physiol 185:297-304.
28. Johnson BN, Sobel N (2007) Methods for building an olfactometer with known concentration outcomes. J Neurosci Methods 160:231-245.
29. Johnson BN, Mainland JD, Sobel N (2003) Rapid olfactory processing implicates subcortical control of an olfactomotor system. J Neurophysiol 90:1084-1094.
30. Kay LM, Freeman WJ (1998) Bidirectional processing in the olfactory-limbic axis during olfactory behavior. Behav Neurosci 112:541-553.
31. Kay LM, Laurent G (1999) Odor- and context-dependent modulation of mitral cell activity in behaving rats. Nat Neurosci 2:1003-1009.
32. Keverne EB (1995) Olfactory learning. Curr Opin Neurobiol 5:482-488.
33. Kobal G, Hummel T, Vantoller S (1992) Differences in human chemosensory evoked-potentials to olfactory and somatosensory chemical stimuli presented to left and right nostrils. Chem Senses 17:233-244.
34. Laffort P, Dravnieks A (1973) An approach to a physico-chemical model of olfactory stimulation in vertebrates by single compounds. J Theor Biol 38:335-345.
35. Laska M, Teubner P (1999) Olfactory discrimination ability for homologous series of aliphatic alcohols and aldehydes. Chem Senses 24:263-270.
36. Mandairon N, Stack C, Kiselycznyk C, Linster C (2006) Broad activation of the olfactory bulb produces long-lasting changes in odor perception. Proc Natl Acad Sci USA 103:13543-13548.
37. Masago R, Shimomura Y, Iwanaga K, Katsuura T (2001) The effects of hedonic properties of odors and attentional modulation on the olfactory event-related potentials. J Physiol Anthropol Appl Human Sci 20:7-13.
38. Moskowitz HR, Dravnieks A, Klarman LA (1976) Odor intensity and pleasantness for a diverse set of odorants. Percept Psychophysiol 19:122-128.
39. Murakami M, Kashiwadani H, Kirino Y, Mori K (2005) State-dependent sensory gating in olfactory cortex. Neuron 46:285-296.
40. Ohloff G (1986) Chemistry of odor stimuli. Experientia 42:271-279.
41. Pager J (1983) Unit responses changing with behavioral outcome in the olfactory bulb of unrestrained rats. Brain Res 289:87-98.
42. Pause BM, Krauel K (2000) Chemosensory event-related potentials (CSERP) as a key to the psychology of odors. Int J Psychophysiol 36:105-122.
43. Richardson JT, Zucco GM (1989) Cognition and olfaction: a review. Psychol Bull 105:352-360.
44. Rinberg d, Koulakov A, Gelperin A (2006) Speed-accuracy tradeoff in olfaction. Neuron 3:351-358.
45. Rolls ET (2004) Convergence of sensory systems in the orbitofrontal cortex in primates and brain design for emotion. Anat Rec A Discov Mol Cell Evol Biol 281:1212-1225.
46. Rolls ET, Kringelbach ML, de Araujo IE (2003) Different representations of pleasant and unpleasant odours in the human brain. Eur J Neurosci 18:695-703.
47. Rossiter KJ (1996) Structureminus signOdor relationships. Chem Rev 96:3201-3240.
48. Royet JP, Zald D, Versace R, Costes N, Lavenne F, Koenig O, Gervais R (2000) Emotional responses to pleasant and unpleasant olfactory, visual, and auditory stimuli: a positron emission tomography study. J Neurosci 20:7752-7759.
49. Schiffman S, Robinson DE, Erickson RP (1977) Multidimensional-scaling of odorants: examination of psychological and physiochemical dimensions. Chem Senses Flav 2:375-390.
50. Schiffman SS (1974) Physicochemical correlates of olfactory quality. Science 185:112-117.
51. Schoenbaum G, Eichenbaum H (1995) Information coding in the rodent prefrontal cortex. I. Single-neuron activity in orbitofrontal cortex compared with that in pyriform cortex. J Neurophysiol 74:733-750.
52. Soussignan R, Schaal B, Marlier L, Jiang T (1997) Facial and autonomic responses to biological and artificial olfactory stimuli in human neonates: Re-examining early hedonic discrimination of odors. Physiol Behav 62:745-758.
53. Steiner JE (1979) Human facial expressions in response to taste and smell stimulation. Adv Child Dev Behav 13:257-295.
54. Stevenson RJ, Repacholi BM (2003) Age-related changes in children's hedonic response to male body odor. Dev Psychol 39:670-679.
55. Tetko IV, Gasteiger J, Todeschini R, Mauri A, Livingstone D, Ertl P, Palyulin VA, Radchenko EV, Zefirov NS, Makarenko AS, Tanchuk VY, Prokopenko VV (2005) Virtual computational chemistry laboratory - design and description. J Comput Aided Mol Des 19:453-463.
56. Wilson DA (2003) Rapid, experience-induced enhancement in odorant discrimination by anterior piriform cortex neurons. J Neurophysiol 90:65-72.
57. Wilson DA, Stevenson RJ (2006) Learning to smell. Baltimore: Johns Hopkins UP.
58. Wilson DA, Best AR, Sullivan RM (2004) Plasticity in the olfactory system: lessons for the neurobiology of memory. Neuroscientist 10:513-524.
59. Wise PM, Cain WS (2000) Latency and accuracy of discriminations of odor quality between binary mixtures and their components. Chem Senses 25:247-265.
60. Wysocki CJ, Pierce JD, Gilbert AN (1991) Geographic, cross-cultural, and individual variation in human olfaction. In: Smell and taste in health and disease (Getchell TV, ed), pp 287-314. New York: Raven.
61. Zakarya D, Yahiaoui M, Fkih-Tetouani S (1993) Structure-odour relations for bitter almond odorants. J Phys Organic Chem 6:627-633.
62. Zald DH, Pardo JV (1997) Emotion, olfaction, and the human amygdala: amygdala activation during aversive olfactory stimulation. Proc Natl Acad Sci USA 94:4119-4124.
63. Zelano C, Bensafi M, Porter J, Mainland J, Johnson B, Bremner E, Telles C, Khan R, Sobel N (2005) Attentional modulation in human primary olfactory cortex. Nat Neurosci 8:114-120.