Pretreatment with sarafotoxin 6c prior to coronary occlusion protects against infarction and arrhythmias via cardiomyocyte mitochondrial K ATP channel activation in the intact rabbit heart during ischemia/reperfusion

Cardiovascular Drugs and Therapy

Volumn 21, Issue 4, 2007, Pages 243-251

  Das, Biswadeep ^a,c   Sarkar, Chayna ^a   Shankar, P Ravi ^b  

^a SIKKIM MANIPAL INSTITUTE OF MEDICAL SCIENCES   (India)

^b MANIPAL COLLEGE OF MEDICAL SCIENCES   (Nepal)

^c AIMST UNIVERSITY   (Malaysia)

Author keywords

Anesthetized rabbit; Coronary occlusion; ETB receptors; HMR 1883; Ischemic preconditioning; Mitochondrial KATP channel; Reperfusion arrhythmia; Sarafotoxin 6c; Sarcolemmal KATP channel

Indexed keywords

ADENOSINE TRIPHOSPHATE; CLAMIKALANT; NITRIC OXIDE; SARAFOTOXIN; SARAFOTOXIN 6C; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANTIARRHYTHMIC ACTIVITY; ARTERIAL PRESSURE; ARTICLE; CONTROLLED STUDY; HEART ARRHYTHMIA; HEART INFARCTION; HEART MUSCLE CELL; HEART PROTECTION; MALE; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; RABBIT;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; ARRHYTHMIAS, CARDIAC; CARDIOTONIC AGENTS; DISEASE MODELS, ANIMAL; MALE; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; NITRIC OXIDE; POTASSIUM CHANNELS; RABBITS; SARCOLEMMA; VIPER VENOMS;

EID: 34548594206     PISSN: 09203206     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10557-007-6031-5     Document Type: Article

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