Very low probability interpretation of V/Q lung scans in combination with low probability objective clinical assessment reliably excludes pulmonary embolism: Data from PIOPED II

Journal of Nuclear Medicine

Volumn 48, Issue 9, 2007, Pages 1411-1415

  Gottschalk, Alexander ^a   Stein, Paul D ^b,c   Sostman, H Dirk ^d   Matta, Fadi ^b   Beemath, Afzal ^b  

^a Michigan State University   (United States)

^b ST JOSEPH MERCY OAKLAND HOSPITAL   (United States)

^c WAYNE STATE UNIVERSITY   (United States)

^d HOUSTON METHODIST HOSPITAL   (United States)

Author keywords

V Q scintigraphy; Venous thromboembolism; Very low probability criteria

Indexed keywords

ADULT; ARTICLE; DIAGNOSTIC IMAGING; DIAGNOSTIC VALUE; FEMALE; FUNCTIONAL ASSESSMENT; HUMAN; LUNG EMBOLISM; LUNG PERFUSION; LUNG SCINTISCANNING; LUNG VENTILATION PERFUSION RATIO; MAJOR CLINICAL STUDY; MALE; PLEURA CAVITY; PRIORITY JOURNAL; PROBABILITY; PROSPECTIVE STUDY; RELIABILITY; VENOUS THROMBOEMBOLISM;

ACUTE DISEASE; ADULT; AGED; AGED, 80 AND OVER; ANGIOGRAPHY, DIGITAL SUBTRACTION; CONTRAST MEDIA; FEMALE; HUMANS; MALE; MIDDLE AGED; PROBABILITY; PROSPECTIVE STUDIES; PULMONARY EMBOLISM; TOMOGRAPHY, SPIRAL COMPUTED; VENTILATION-PERFUSION RATIO;

EID: 34548587073     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.107.040998     Document Type: Article

References (22)

1. Hull RD, Raskob GE. Low-probability lung scan findings: a need for change. Ann Intern Med. 1991;114:142-143.
2. The PIOPED Investigators. Value of the ventilation/perfusion scan in acute pulmonary embolism: results of the Prospective Investigation of Pulmonary Embolism Diagnosis (PIOPED). JAMA. 1990;263:2753-2759.
3. Stein PD, Gottschalk A. Review of criteria appropriate for a very low probability of pulmonary embolism on ventilation-perfusion lung scans: a position paper. Radiographics. 2000;20:99-105.
4. Stein PD, Woodard PK, Weg JG, et al. Diagnostic pathways in acute pulmonary embolism: recommendations of the PIOPED II investigators. Am J Med. 2006;119:1048-1055.
5. Stein PD, Fowler SE, Goodman LR, et al. Multidetector computed tomography for acute pulmonary embolism. N Eng J Med. 2006;354:2317-2327.
6. Gottschalk A, Stein PD, Goodman LR, Sostman HD. Overview of Prospective Investigation of Pulmonary Embolism Diagnosis II. Semin Nucl Med. 2002;32:173-182.
7. Stein PD, Relyea B, Gottschalk A. Evaluation of the positive predictive value of specific criteria used for the assessment of low probability ventilation/perfusion lung scans. J Nucl Med. 1996;37:577-581.
8. Stein PD, Henry JW, Gottschalk A. Small perfusion defects in suspected pulmonary embolism. J Nucl Med. 1996;37:1313-1316.
9. Gottschalk A, Stein PD, Henry JW, Relyea B. Matched ventilation/perfusion defects and chest radiographic abnormalities: re-evaluation of the triple matched defect in the assessment of acute pulmonary embolism. J Nucl Med. 1996;37:1636-1638.
10. Sostman HD, Gottschalk A. The stripe sign: a new sign for diagnosis of nonembolic defects on pulmonary perfusion scintigraphy. Radiology. 1982;142:737-741.
11. Sostman HD, Gottschalk A. Prospective validation of the stripe sign in ventilation-perfusion scintigraphy. Radiology. 1992;184:455-459.
12. Wells PS, Anderson DR, Roger M, et al. Excluding pulmonary embolism at the bedside without diagnostic imaging: management of patients with suspected pulmonary embolism presenting to the emergency department by using a simple clinical model and D-dimer. Ann Intern Med. 2001;135:98-107.
13. Parker MS, Hui FK, Camacho MA, Chung JK, Broga DW, Sethi N. Female breast radiation exposure during CT pulmonary angiography. AJR. 2005;185:1228-1233.
14. Milne ENC. Female breast radiation exposure [letter]. AJR. 2006;186:E24.
15. Gottschalk A, Sostman HD, Coleman RE, et al. Ventilation-perfusion scintigraphy in the PIOPED study. Part II. Evaluation of scintigraphic criteria and interpretations. J Nucl Med. 1993;34:1119-1126.
16. Perrier A, Howarth N, Didier D, et al. Performance of helical computed tomography in unselected outpatients with suspected pulmonary embolism. Ann Intern Med. 2001;135:88-97.
17. Perrier A, Roy P-M, Sanchez O, et al. Multidetector-row computed tomography in suspected pulmonary embolism. N Engl J Med. 2005;352:1760-1768.
18. The Christopher Study Investigators. Effectiveness of managing suspected pulmonary embolism using an algorithm combining clinical probability, D-dimer testing, and computed tomography. JAMA. 2006;295:172-179.
19. van Strijen MJL, de Monye W, Schiereck J, et al. Single-detector helical computed tomography as the primary diagnostic test in suspected pulmonary embolism: a multicenter clinical management study of 510 patients. Ann Int Med. 2003;138:307-314.
20. Revel MP, Petrover D, Hernigou A, Lefort C, Meyer G, Frija G. Diagnosing pulmonary embolism with four-detector row helical CT: prospective evaluation of 216 outpatients and inpatients. Radiology. 2005;234:265-273.
21. Kelly AM, Patel S, Carlos RC, Cronin P, Kazerooni EA. Multidetector row CT pulmonary angiography and indirect venography for the diagnosis of venous thromboembolic disease in intensive care unit patients. Acad Radiol. 2006;13:486-495.
22. Worsley DF, Alavi A, Palevsky HI, Kundel HL. Comparison of diagnostic performance with ventilation-perfusion lung imaging in different patient populations. Radiology. 1996;199:481-483.